| Function | Number | Gene | Relative PPL |
1.Amino acid biosynthesis | | | | |
1.1 Aromatic amino acid family | | | | |
| e3-phosphoshikimate 1-carboxyvinyltransferase EC2.5.1.19 | g1787137 | aroA | 0.0352 |
| 3-dehydroquinate Sase EC4.6.1.3 | g1789791 | aroB | -0.7591 |
| chorismate Sase EC4.6.1.4 | g1788669 | aroC | 0.1334 |
| 3-dehydroquinate dehydratase EC4.2.1.10 | g1787984 | aroD | 0.1215 |
| shikimate 5-DHase EC1.1.1.25 | g1789675 | aroE | -1.3242 |
| phospho-2-dehydro-3-deoxyheptonate aldolase EC4.1.2.15 | g1788953 | aroF | -0.0314 |
| DAHP Sase EC4.1.2.15 | g1786969 | aroG | 0.092 |
| 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase EC4.1.2.15 | g1787996 | aroH | -0.6203 |
| shikimic acid kinase EC2.7.1.71 | g1789792 | aroK | -0.4301 |
| shikimate kinase II EC2.7.1.71 | g1786587 | aroL | -1.3794 |
| chorismate mutase-prephenate dehydratase | 1145 | pheA | -0.5517 |
| Trp Sase a chain EC4.2.1.20 | g1787514 | trpA | -0.4133 |
| Trp Sase b chain EC4.2.1.20 | g1787515 | trpB | 0.3241 |
| anthranilate isomerase EC4.1.1.48 | g1787516 | trpC | -0.6138 |
| anthranilate Sase component II EC4.1.3.27/EC2.4.2.18 | g1787517 | trpD | -0.0175 |
| anthranilate Sase component I EC4.1.3.27 | g1787518 | trpE | -0.0388 |
| chorismate mutase/prephenate dehydrogenase EC5.4.99.5/EC1.3.1.12 | g1788952 | tyrA | -0.2288 |
| tyrosine aminotransferase EC2.6.1.5/EC2.6.1.57 | g1790488 | tyrB | -1.1446 |
1.2 Histidine | | | | |
| EC5.3.1.16 | g1788335 | hisA | 0.745 |
| imidazoleglycerol-P dehydratase EC3.1.3.15/EC4.2.1.19 | g1788333 | hisB | 0.4553 |
| histidinol-P ATase EC2.6.1.9 | g1788332 | hisC | 0.3143 |
| histidinol dehydrogenase EC1.1.1.23 | g1788331 | hisD | 0.6182 |
| phosphoribosyl-AMP cyclohydrolase EC3.5.4.19/EC3.6.1.31 | g1788337 | hisIE | 0.1308 |
| cyclase | g1788336 | hisF | 0.3994 |
| ATP PRTase (hisG) EC2.4.2.17 | g1788330 | hisG | 0.8779 |
| Gln amidotransferase EC2.4.2.- | g1788334 | hisH | 1.0118 |
"1.3 Aspartate family (lysine, methionine, threonine)" | | | | |
| Asp-semialdehyde DHase EC1.2.1.11 | g1789841 | asd | 0.1041 |
| Asn Sase EC6.3.1.1 | g1790183 | asnA | 0.8979 |
| asparagine synthetase B EC6.3.5.4 | g1786889 | asnB | 0.7821 |
| Asp ATase EC2.6.1.1 | g1787159 | aspC | 0.7143 |
| dehydrodipicolinate RDase EC1.3.1.26 | g1786214 | dapB | -0.0008 |
| tetrahydrodipicolinate N-succinyltransferase EC2.3.1.117 | g1786362 | dapD | 1.3048 |
| succinyl-diaminopimelate desuccinylase EC3.5.1.18 | g1788816 | dapE | -0.6935 |
| diaminopimelate epimerase EC5.1.1.7 | g1790242 | dapF | -0.2948 |
| diaminopimelate DCase EC4.1.1.20 | g1789203 | lysA | -0.3019 |
| aspartokinase III EC2.7.2.4 | g1790455 | lysC | 0.277 |
| homoserine O-succinyltransferase EC2.3.1.46 | g1790443 | metA | 0.3597 |
| cystathionine g-Sase | g1790375 | metB | -0.151 |
| b-cystahionase EC4.4.1.8 | g1789383 | metC | 0.6525 |
| tetrahydropteroyltriglutamate MTase EC2.1.1.14 | g1790263 | metE | 0.8213 |
| B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase EC2.1.1.13 | g1790450 | metH | 0.685 |
| aspartokinase II/homoserine dehydrogenase II EC2.7.2.4 | g1790376 | metL | 0.5505 |
| aspartokinase-homoserine DHase EC2.7.2.4 | g1786183 | thrA | -0.106 |
| homoserine kinase EC 2.7.1.39 | g1786184 | thrB | -0.4512 |
| Thr Sase EC4.2.99.2 | g1786185 | thrC | -0.024 |
1.4 Branched chain family (methionine) | | | | |
"(isoleucine, isoleucine)" | | | | |
| "acetohydroxy acid synthase I, small subunit EC4.1.3.18" | g1790104 | ilvB | -0.0118 |
| dihydroxyacid dehydrase EC4.2.1.9 | g1790206 | ilvD | 1.0471 |
| branched-chain amino-acid aminotransferase EC2.6.1.42 | g1790205 | ilvE | 1.1615 |
| acetohydroxyl acid Sase II | g1790203 | ilvG | 0.3773 |
| acetolactate Sase III small chain EC4.1.3.18 | g1786266 | ilvH | -1.1597 |
| acetolactate Sase III large chain EC4.1.3.18 | g1786265 | ilvI | -0.808 |
| "acetohydroxy acid synthase II, small subunit EC4.1.3.18" | g1790204 | ilvM | -1.06 |
| "acetohydroxy acid synthase I, small subunit EC4.1.3.18" | g1790103 | ilvN | 0.4548 |
| valine--pyruvate aminotransferase EC2.6.1.66 | g1789996 | avtA | -0.1376 |
(leucine) | | | | |
| a isopropylmalate Sase EC4.1.3.12 | g1786261 | leuA | 0.6777 |
| 3-isopropylmalate DHase EC1.1.1.85 | g1786260 | leuB | 0.4197 |
| 3-isopropylmalate dehydratase EC4.2.1.33 | g1786259 | leuC | 0.8572 |
| 3-isopropylmalate dehydratase EC4.2.1.33 | g1786258 | leuD | 0.5276 |
(Others) | | | | |
| threonine deaminase; threonine dehydratase biosynthetic EC4.2.1.16 | g1790207 | ilvA | 0.4384 |
| ketol acid reductoisomerase EC1.1.1.86 | g1790210 | ilvC | 2.0352 |
| lysine decarboxylase EC4.1.1.18 | g1786384 | ldcC | -0.6752 |
1.5 Glutamate family | | | | |
(arginine biosynthesis) | | | | |
| N-acetylglutamate synthase EC2.3.1.1 | g1789181 | argA | -0.2615 |
| N-acetylglutamate kinase EC2.7.2.8 | g1790397 | argB | -0.087 |
| N-acetyl-gamma-glutamyl-phosphate reductase EC1.2.1.38 | g1790396 | argC | -0.2395 |
| N-acetylornitine delta-aminotransferase EC2.6.1.11 | g1789759 | argD | 0.1703 |
| acetylornithine deacetylase EC3.5.1.16 | g1790395 | argE | -0.76 |
| ornithine carbamoyltransferase chain F EC2.1.3.3 | g1786469 | argF | 0.4378 |
| arginosuccinate Sase EC6.3.4.5 | g1789563 | argG | 1.1416 |
| arginosuccinate lyase EC4.3.2.1 | g1790398 | argH | 0.5831 |
| ornithine carbamoyltransferase EC2.1.3.3 | g1790703 | argI | -0.4599 |
(polyamine biosynthesis) | | | | |
? | putrescine transport ATP-binding protein | g1787079 | potG | 0.0125 |
| arginine decarboxylase EC4.1.1.19 | g1789307 | speA | 1.1242 |
| agmatine ureohydrolase EC3.5.3.11 | g1789306 | speB | 1.3329 |
| ornithine decarboxylase EC4.1.1.17 | g1789337 | speC | -0.7851 |
| s-adenosylmethionine decarboxylase proenzyme EC4.1.1.50 | g1786311 | speD | -0.2935 |
| spermidine synthase | g1786312 | speE | 0.1806 |
| ornithine DCase EC4.1.1.17 | g1786909 | speF | 0.0087 |
| spermidine N1-acetyltransferase EC2.3.1.57 | g1787867 | speG | -0.3581 |
(glutamate biosynthesis) | | | | |
| glutamate synthase (NADPH) large chain EC1.4.1.13/EC2.6.1.53 | g1789605 | gltB | 0.8096 |
| glutamate synthase (NADPH) small chain EC1.4.1.13/EC2.6.1.53 | g1789606 | gltD | -0.9723 |
(glutamine biosynthesis) | | | | |
| Gln Sase EC6.3.1.2 | g1790301 | glnA | 2.2493 |
(prorine biosynthesis) | | | | |
| g-glutamyl kinase EC2.7.2.11 | g1786437 | proB | 0.4857 |
| d-1-pyrroline-5-carboxylate RDase EC1.5.1.2 | g1786585 | proC | -0.0189 |
(Others) | | | | |
| cyanate lyase (cyanate hydrolase) (cyanase) EC4.3.99.1 | g1786535 | cynS | -0.1339 |
| 4-aminobutyrate aminotransferase EC2.6.1.19 | g1789016 | gabT | 0.4826 |
| probable ornithine aminotransferase EC2.6.1.13 | g1789454 | ygjG | -0.366 |
"1.6 Serine family (Serine, Glycine, Cysteine)" | | | | |
(serine) | | | | |
| D-3-phosphoglycerate DHase EC1.1.1.95 | g1789279 | serA | 0.7549 |
| phosphoserine phosphatase EC3.1.3.3 | g1790849 | serB | 0.4273 |
| phosphoserine ATase EC2.6.1.52 | g1787136 | serC | 0.1235 |
(glycine) | | | | |
| Ser hydroxymethltrasferase | | glyA | 2.251 |
(cysteine) | | | | |
| adenosine 5-phosphosulfate kinase EC2.7.1.25 | g1789107 | cysC | -1.0304 |
| ATP sulfurylase (ATP:sulfate adenyltransferase) EC2.7.7.4 | g1789109 | cysD | 0.8744 |
| Ser acethyltransferase EC2.3.1.30 | g1790035 | cysE | 0.0571 |
| siroheme synthesis | g1789768 | cysG | -0.3035 |
| 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase EC2.8.2. | g1789121 | cysH | 0.1037 |
| sulfite reductase (NADPH) hemoprotein alpha subunit EC1.8.1.2 | g1789122 | cysI | 0.6585 |
| sulfite reductase (NADPH) flavoprotein beta subunit EC1.8.1.2 | g1789123 | cysJ | 0.1777 |
| Cys Sase EC4.2.99.8 | g1788754 | cysK | 0.2617 |
| ATP sulfurylase (ATP:sulfate adenyltransferase) subunit EC2.7.7.4 | g1789108 | cysN | 0.4048 |
| | | | |
"2.Biosynthesis of cofactors, prosthetic groups, and carriers" | | | | |
2.1 Biotin | | | | |
| "7,8-diamino-pelargonic acid ATase EC2.6.1.62" | g1786991 | bioA | -0.2609 |
| biotin synthesis prt | g1786994 | bioC | -1.4048 |
| dethiobiotin Sase EC6.3.3.3 | g1786995 | bioD | -0.7791 |
| 7-keto-8-aminopelargonic acid Sase EC2.3.1.47 | g1786993 | bioF | -0.5832 |
| "biotin synthesis, block prior to pimeloyl CoA" | g1789817 | bioH | -0.6793 |
| biotin operon repressor/andbiotin-[acetyl-CoAcarboxylase]synthetase EC6.3.4.15 | g1790408 | birA | -0.7468 |
| biotin sulfoxid RDase EC1.-.-.- | g1789973 | bisC | -0.283 |
2.2 Cobalamine (Vitamin B12) | | | | |
| COB(I) alamin adenosyltransferase EC2.5.1.17 | g1787525 | btuR | -1.4688 |
| cobalamin (5'-phosphate) synthase | g1788301 | cobS | -0.9062 |
| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase EC2.4.2.21 | g1788300 | cobT | -0.9847 |
| cobinamide kinase and guanylyltransferase | g1788302 | cobU | -1.7632 |
| ethanolamine ammonia-lyase heavy chain | g1788782 | eutB | 0.7246 |
| ethanolamine ammonia-lyase light chain EC4.3.1.7 | g1788781 | eutC | 0.8849 |
2.3 Folic acid | | | | |
| "5,10-methylenetetrahydrofolate RDase EC1.7.99.5" | g1790377 | metF | 0.2969 |
| "5,10-methylenetetrahydrofolate RHase EC1.5.1.5" | g1786741 | folD | 0.315 |
| "7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase EC2.7.6.3" | g1786335 | folK | -0.4288 |
| aminodeoxychorismate lyase EC4.-.-.- | g1787338 | pabC | -1.6724 |
| dedA | g1788656 | dedA | -0.287 |
| "dihydrofolate RDase, type I EC1.5.1.3" | g1786233 | folA | -0.7267 |
| dihydropteroate Sase EC2.5.1.15 | g1789567 | folP | -0.6405 |
| folylpolyglutamate Sase EC6.3.2.17 | g1788654 | folC | -0.246 |
| GTP cyclohydrolase I EC3.5.4.16 | g1788476 | folE | -0.0567 |
| p-aminobenzoate Sase EC4.1.3.- | g1788114 | pabB | -0.6792 |
2.4 Heme and porphyrin | | | | |
| glutamyl-tRNA reductase EC1.2.1.- | g1787461 | hemA | -0.2852 |
| delta-aminolevulinic acid dehydratase EC4.2.1.24 | g1786566 | hemB | 0.2904 |
| porphobilinogen deaminase EC4.3.1.8 | g1790237 | hemC | -0.6387 |
| uroporphyrinogen III synthase EC4.2.1.75 | g1790236 | hemD | -1.1088 |
| uroporphyrinogen decarboxylase EC4.1.1.37 | g1790430 | hemE | 0.2346 |
| coproporphyrinogen III oxidase EC1.3.3.3 | g1788777 | hemF | -0.6824 |
| ferrochelatase EC4.99.1.1 | g1786681 | hemH | -0.3559 |
| possibly protoporphyrinogen oxidase | g1787463 | hemK | -0.6148 |
| "glutamate-1-semialdehyde 2,1-aminomutase EC5.4.3.8" | g1786349 | hemL | 0.6623 |
| HemM protein | g1787460 | hemM | -0.531 |
| oxygen-independent coproporphyrinogen III oxidase EC1.-.-.- | g1790298 | hemN | 0.4754 |
| uroporphyrinogen III methylase EC2.1.1.107 | g1790235 | hemX | 0.3114 |
| HemY protein | g1790234 | hemY | 0.0447 |
| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EC4.1.1.- | g1788650 | ubiX | -1.0098 |
2.5 Lipoate | | | | |
| lipoate biosyn prt A =lipoic acid synthetase | g1786846 | lipA | 0.7438 |
| lipoate biosyn prt B | g1786848 | lipB | -0.9965 |
2.6 Menaquinone and ubiquinone | | | | |
| menaquinone biosynthesis | g1790365 | menA | -0.4564 |
| dihydroxynaphthoic acid Sase EC4.1.3.36 | g1788597 | menB | 2.155 |
| 4-(2'-carboxyphenyl0-4-oxybutyric acid Sase | g1788596 | menC | -0.4413 |
| "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Sase" | g1788599 | menD | -0.1237 |
| O-succinylbenzoate-CoA EC6.2.1.26 | g1788595 | menE | -0.5376 |
| menaquinone biosynthesis protein meng | g1790364 | memG | 0.6259 |
| 4-hydroxybenzoate-octaprenyl transferase EC2.5.1.- | g1790473 | ubiA | -1.5162 |
| flavin reductase EC1.6.8.- | g1790278 | ubiB | -0.3883 |
| chorismate lyase | g1790472 | ubiC | -0.6316 |
| 3-demethylubiquinone-9 3-methyltransferase EC2.1.1.64 | g1788564 | ubiG | -0.5065 |
| EC1.14.13.- | g1789274 | ubiH | -0.3122 |
2.7 Molybdopterin | | | | |
| molybdenum biosyn prt A | g1786999 | moaA | 0.2187 |
| molybdenum cofactor biosynthesis protein B | g1787000 | moaB | 0.1446 |
| molybdenum biosyn prt C | g1787001 | moaC | 0.1753 |
| "molybdopterin converting factor, sub 1" | g1787002 | moaD | -0.5353 |
| "molybdopterin converting factor, sub 2" | g1787003 | moaE | -0.0272 |
| biosynthesis of molybdopterin=molybdopterin-guanine dinucleotide biosynthesis | g1790288 | mobA | -1.6314 |
| molybdopterin biosynthesis | g1787049 | moeA | 0.1155 |
| molybdopterin biosynthesis | g1787048 | moeB | -0.0026 |
| molybdopterin biosynthesis Mog protein | g1786190 | mog | -0.2344 |
2.8 Pantothenate | | | | |
| pantothenate metabolism flavoprotein | g1790070 | dfp | -0.6415 |
| pantothenate kinase EC2.7.1.33 | g1790409 | coaA | -1.0604 |
| converts alpha-ketoisovalerate to alpha-ketopantoate EC2.1.2.11 | g1786326 | panB | 0.6672 |
| pantoate--beta-alanine ligase EC6.3.2.1 | g1786325 | panC | 0.1738 |
| aspartate 1-decarboxylase EC4.1.1.11 | g1786323 | panD | -0.1682 |
2.9 Pyridoxine (Vitamin B6) | | | | |
| pyridoxal phosphate biosynthetic protein PdxA | g1786237 | pdxA | -0.7431 |
| erythronate-4-phosphate dehydrogenase EC1.1.1.- | g1788660 | pdxB | -0.5082 |
| pyridoxamine phosphate oxidase EC1.4.3.5 | g1787926 | pdxH | -0.5303 |
| pyridoxal phosphate biosynthetic protein | g1788917 | pdxJ | 1.0875 |
2.10 Nicotinate and nicotinamide (NAD) | | | | |
| nicotinate-nucleotide pyrophosphorylase EC2.4.2.19 | g1786299 | nadC | -0.5709 |
| NH3-dependent NAD synthetase EC6.3.5.1 | g1788036 | nadE | -0.196 |
| nicotinate phosphoribosyltransferase EC2.4.2.11 | | pncB | -0.2253 |
2.11 Quinolinate (NAD) | | | | |
| quinolinate synthetase A protein | g1786964 | nadA | -0.939 |
| l-aspartate oxidase (quinolinate synthetase B) EC1.4.3.16 | g1788928 | nadB | -0.8046 |
2.12 Riboflavin | | | | |
| GTP cyclohydrolase II EC3.5.4.25 | g1787533 | ribA | 0.0425 |
| "3,4-dihydroxy-2-butanone 4-P Sase" | g1789420 | ribB | 0.5668 |
| riboflavin biosynthesis protein | g1786616 | ribD | -0.8384 |
| probable riboflavin synthase beta chain EC2.5.1.9 | g1786617 | ribH | 1.5523 |
2.13 Thiamin | | | | |
| thiamine biosynthesis | g1790427 | thiC | 0.2342 |
| thiamine biosynthesis | g1790426 | thiE | -0.8181 |
| thiamine biosynthesis | g1790425 | thiF | -1.1097 |
| thiamine biosynthesis | g1790424 | thiG | -0.2781 |
| thiamine biosynthesis | g1790423 | thiH | -0.6186 |
| (4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis | g1786626 | thiJ) | 0.4719 |
"2.14 Thioredoxin, glutaredoxin, and glutathione" | | | | |
| gamma-glutamyltranspeptidase EC2.3.2.2 | g1789856 | ggt | -0.3033 |
| glutaredoxin 2 | g1787303 | grxB | -0.2953 |
| glutaredoxin 3 (grx3) | g1790039 | grxC | 0.5399 |
| (gamma-glutamylcysteine synthetase EC6.3.2.2 | g1789044 | gshA) | 0.1602 |
| glutathione synthetase EC6.3.2.3 | g1789316 | gshB | 0.6793 |
| glutathione s-transferase EC2.5.1.18 | g1787923 | gst | -0.0811 |
| glutathione RDase EC1.6.4.2 | g1789915 | gor | 0.8473 |
| thioredoxin | g1790215 | trxA | 0.3625 |
3. Cell envelope | | | | |
"3.1 Membranes, lipoproteins, and porins" | | | | |
(Outer membrane) | | | | |
| outer membrane porin protein | g1786765 | nmpC | 1.1106 |
| outer membrane prt P5 | g1787191 | ompA | 2.8216 |
| outer membrane protein F | g1787160 | ompF | 1.6839 |
| outer membrane protein C | g1788544 | ompC | 2.6938 |
| outer membrane protein X | g1787034 | ompX | 2.2185 |
| outer membrane pore protein E | g1786436 | phoE | -0.3608 |
(Lipoproteins) | | | | |
| 15kD peptidoglycan-assoc lpp=major outer membrane lipoprotein | g1787967 | lpp | 2.3447 |
| lipoprotein-28 | g1790093 | nlpA | -1.3837 |
| lipoprotein-34 | g1788822 | nlpB | 0.9912 |
| probable lipoprotein | g1788001 | nlpC | -0.7569 |
| lpp | g1789099 | nlpD | -0.5705 |
| rare lppA | g1786852 | rlpA | -0.7776 |
| rare lppB | g1786860 | rlpB | 0.2286 |
| apolipoprotein N-acyltransferase EC2.3.1.- | g1786878 | lnt | 0.3172 |
| prolipoprotein diacylglyceryl Tase EC2.4.99.- | g1789192 | lgt | 0.5437 |
| osmotically inducible lipoprotein B | g1787539 | osmB | -0.967 |
| peptidoglycan-associated lipoprotein | g1786962 | pal | 2.6299 |
| VacJ lipoprotein | g1788688 | vacJ | -0.0105 |
(Others) | | | | |
| inner membrane protein | g1790862 | creD | -0.948 |
| membrane associated protein | g1787901 | gusC | -1.6284 |
| peripheral membrane protein U | g1790161 | phoU | 1.3821 |
3.2 Murein sacculus and peptidoglycan | | | | |
| "Ala racemase, biosynthetic EC5.1.1.1" | g1790487 | alr | -0.1844 |
| probable n-acetylmuramoyl-l-alanine amidase EC3.5.1.28 | g1788776 | amiA | -0.4289 |
| N-acetylmuramoyl-L-Ala amidase EC3.5.1.28 | g1790611 | amiB | -0.5943 |
| "D-alanyl-D-Ala carboxypeptidase, fraction B EC3.4.16.4" | g1789573 | dacB | -0.6873 |
| penicillin-binding protein 6 | g1787062 | dacC | 0.3076 |
| D-alanine--D-alanine ligase A EC6.3.2.4 | g1786579 | ddlA | 0.0141 |
| D-Ala-D-Ala ligase EC6.3.2.4 | g1786280 | ddlB | -0.483 |
| penicillin tolerance and control of the stringent response | g1786212 | lytB | 0.9776 |
| membrane-bound lytic murein transglycosylase A EC3.2.1.- | g1789179 | mltA | 0.639 |
| membrane-bound lytic transglycosylase B EC3.2.1.- | g1789053 | mltB | 0.1107 |
| peptidoglycan synthetase; cell wall synthesis | g1789799 | mrcA | 0.3603 |
| "penicillin-BP 1B alternate gene names ponB, pbpF" | 1725 | mrcB | 0.5249 |
| (PBP2 | g1786854 | mrdA) | 0.3729 |
| rod shape-determining protein rodA | g1786853 | mrdB | -0.4145 |
| phospho-N-acetylmuramoyl-pentapeptide Tase E EC2.7.8.13 | g1786275 | mraY | 0.7708 |
| rod shape-determining prt | g1789649 | mreB | 1.1919 |
| rod shape-determining prt | g1789648 | mreC | 0.1898 |
| rod shape-determining prt | g1789647 | mreD | -1.1542 |
| udp-n-acetylglucosamine 1-carboxyvinyltransferase EC2.5.1.7 | g1789580 | murA | 0.8947 |
| UDP-NAc-enolpyruvoylglucosasmine RDase EC1.1.1.158 | g1790407 | murB | -1.4896 |
| UDP-MurNAc-Ala ligase EC6.3.2.8 | g1786279 | murC | 0.3312 |
| UDP-MurNAc-Ala-D-Glu ligase EC6.3.2.9 | g1786276 | murD | 0.0701 |
| UDP-MurNAc-pentapeptide Sase=D-alanyl:D-alanine-adding enzyme | g1786274 | murF | 0.2633 |
| UDP-MurNAc-tripeptide Sase | g1786273 | murE | 0.2221 |
| GlcNAc transferase | g1786278 | murG | -0.2342 |
| glutamate racemase EC5.1.1.3 | g1790406 | murI | -0.7947 |
| penicillin-binding protein 7 precursor (pbp-7) | g1788455 | pbpG | -0.3155 |
| soluble lytic murein transglycosylase EC3.2.1.- | g1790853 | slt | -0.5004 |
"3.3 Surface polysaccharides, lipopolysaccharides and antigens" | | | | |
| phosphoheptose isomerase | g1786416 | gmhA | 1.0689 |
| 2-dehydro-3-deoxyphosphooctonate aldolase EC4.1.2.16 | g1787466 | kdsA | 1.0284 |
| CTP:CMP-3-deoxy-D-manno-octulosonate-cytidylyl-transferase EC2.7.7.38 | g1787147 | kdsB | -0.3767 |
| 3-deoxy-D-manno-octulosonic-acid Tase EC2.-.-.- | g1790064 | kdtA | -0.0952 |
| UDP-GlcNAc acethyltransferase EC2.3.1.129 | g1786378 | lpxA | 0.2384 |
| lipid A disaccharide Sase | g1786379 | lpxB | -0.5034 |
| udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase | g1786285 | lpxC | 0.6677 |
| periplasmic glucans biosynthesis protein | g1787286 | mdoG | 0.014 |
| EC2.4.1.- | g1790058 | rfaB | -2.0098 |
| lipopolysaccharide heptosyltransferase-1 | g1790051 | rfaC | -1.5519 |
| ADP-L-glycero-D-mannoheptose-6-epimerase EC5.1.3.- | g1790049 | rfaD | 1.6481 |
| ADP-heptose-lps heptosyltransferase II | g1790050 | rfaF | -0.5273 |
| glucosyltransferase I | g1790061 | rfaG | -2.0594 |
| EC2.4.1.44 | g1790057 | rfaI | -2.1583 |
| UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase EC2.4.1.58 | g1790056 | rfaJ | -2.4799 |
| "lipopolysaccharide 1,2-n- acetylglucosaminetransferase EC2.4.-.-" | g1790053 | rfaK | -2.2763 |
| Lipopolysaccharide core biosynthesis; phosphorylationofcoreheptose | g1790060 | rfaP | -1.7286 |
| lipopolysaccharide core biosynthesis | g1790062 | rfaQ | -1.5972 |
| lipopolysaccharide core biosynthesis | g1790059 | rfaS | -2.612 |
| lipopolysaccharide core biosynthesis | g1790055 | rfaY | -1.3239 |
| lipopolysaccharide core biosynthesis | g1790054 | rfaZ | -1.781 |
| TDP-glucose pyrophosphorylase EC2.7.7.24 | g1788351 | rfbA | -0.9452 |
| "dtdp-glucose 4,6-dehydratase EC4.2.1.46" | g1788353 | rfbB | -1.2725 |
| "dTDP-4-dehydrorhamnose 3,5-epimerase EC5.1.3.13" | g1788350 | rfbC | -2.4584 |
| putative o-antigen transporter | g1788349 | rfbX | -2.4052 |
| o-antigen polymerase | g1788347 | rfc | -2.5355 |
| rfe prt | g1790218 | rfe | -0.3377 |
| UDP-ManNAc dehydrogenase | g1790221 | rrfD | -0.2605 |
| UDP-N-acetylglucosamine epimerase (UDP-GlcNAc-2-epimerase) | g1790223 | rffG | 0.7472 |
| probable UDP-N-acetyl-D-mannosaminuronic acid transferase | g1790229 | rffM | -0.1769 |
| biosynthesis of enterobacterial common antigen EC2.4.1.- | g1790228 | rffT | -0.4654 |
| GDP-d-mannose dehydratase | g1788366 | yefA | 1.554 |
3.4 Surface structures | | | | |
(Fimbriae) | | | | |
| adhesin B precursor=type 1 fimbrial subunit | g1790769 | fimA | 0.8613 |
| outer membrane usher protein | g1790772 | fimD_2 | -1.352 |
| outer membrane usher protein | g1786332 | htrE | -1.2321 |
| regulation of length and mediation of adhesion of type1 fimbriae | g1790773 | fimF | -1.5611 |
| regulation of length and mediation of adhesion of type1 fimbriae | g1790774 | fimG | -1.1686 |
| regulation of length and mediation of adhesion of type1 fimbriae | g1790775 | fimH | -1.5398 |
| fimbriae Z protein | g1786747 | fimZ | -2.0375 |
(Flagella) | | | | |
| flagellar basal body P-ring protein | g1787312 | flgA | -1.2711 |
| putative flagellar basal-body rod protein | g1787313 | flgB | -0.637 |
| putative flagellar basal-body rod protein | g1787314 | flgC | -0.6731 |
| flagellar hook formation protein | g1787315 | flgD | -0.3835 |
| flagellar hook protein | g1787316 | flgE | 0.5274 |
| putative flagellar basal-body rod protein (proximal rod protein) | g1787317 | flgF | -0.625 |
| flagellar basal-body rod protein (distal rod protein) | g1787318 | flgG | 0.1103 |
| flagellar L-ring protein precursor | g1787319 | flgH | -0.3764 |
| flagellar P-ring protein precursor | g1787320 | flgI | -0.6713 |
| flagellar protein | g1787321 | flgJ | -0.3292 |
| flagellar hook-associated protein 1 | g1787323 | flgK | -0.0977 |
| flagellar hook-associated protein 3 | g1787324 | flgL | -0.2398 |
| flagella synthesis protein | g1787310 | flgN | -1.1673 |
| flagellar biosynthesis protein | g1788187 | flhA | -0.8665 |
| flagellin | g1788232 | fliC | 1.0158 |
| flagellar hook associated protein 2 | g1788233 | fliD | -0.6706 |
| flagellar hook-basal body complex protein | g1788247 | fliE | -0.6752 |
| flagellar basal-body M-ring protein | g1788248 | fliF | -0.2424 |
| flagellar motor switch protein | g1788249 | fliG | 0.1515 |
| flagellar biosynthesis | g1788250 | fliH | -0.9546 |
| flagellum-specific ATP synthase EC3.6.1.34 | g1788251 | fliI | -0.2873 |
| flagellar FliJ protein | g1788252 | fliJ | -1.2063 |
| (hook-length control protein | g1788253 | fliK) | -0.7553 |
| flagellar biosynthesis | g1788254 | fliL | -0.4569 |
| (flagellar motor switch protein | g1788255 | fliM) | 0.0701 |
| (flagellar motor switch protein | g1788256 | fliN) | 0.2007 |
| flagellar synthesis | g1788258 | fliO | -1.0395 |
| flagellar biosynthetic protein | g1788259 | fliP | -0.0184 |
| flagellar biosynthetic protein | g1788260 | fliQ | -1.2783 |
| flagellar biosynthetic protein | g1788261 | fliR | -0.4949 |
| flagellar synthesis | g1788234 | fliS | -1.4632 |
| flagellar synthesis | g1788235 | fliT | -1.0831 |
| FliY protein precursor | g1788228 | fliY | 0.7922 |
| FliZ protein | g1788230 | fliZ | -0.9378 |
| motility protein A | g1788199 | motA | -0.3112 |
| motility protein B | g1788198 | motB | -1.0154 |
4. Cellular processes | | | | |
4.1 General | | | | |
| chemotaxis protein CheA EC2.7.3.- | g1788197 | cheA | -0.7061 |
| protein-glutamate methylesterase EC3.1.1.61 | g1788192 | cheB | -0.224 |
| chemotaxis protein methyltransferase EC2.1.1.80 | g1788193 | cheR | -0.2432 |
| purine binding chemotaxis protein | g1788196 | cheW | -0.5645 |
| chemotactic signal transduction | g1788191 | cheY | -0.7478 |
| chemotactic signal transduction | g1788190 | cheZ | -1.0139 |
| haemolysin expression modulating protein | g1786665 | hha | -0.8242 |
| chemotaxis protein IV | g1788194 | tap | -0.5747 |
| methyl-accepting chemotaxis protein I | g1790815 | tsr | 0.0958 |
| methyl-accepting chemotaxis protein II | g1788195 | tar | -0.5202 |
| methyl-accepting chemotaxis protein III | g1787690 | trg | -1.2944 |
4.2 Cell division | | | | |
| cytoplasmic axial filament prt | g1789645 | cafA | 0.1474 |
| division inhibition protein | g1787857 | dicB | -1.7976 |
| filamentation in presence of cyclic AMP in mutant | g1789761 | fic | -0.1771 |
| cell division prt | g1786282 | ftsA | -0.4512 |
| cell division ATP-BP | g1789873 | ftsE | 0.1278 |
| penicillin-BP 3 | g1786272 | ftsI | 0.0305 |
| cell division prt | g1789569 | ftsJ | -0.1505 |
| cell division protein | g1787117 | ftsK | -0.1809 |
| cell division prt | g1786271 | ftsL | -1.1704 |
| cell division protein ftsn | g1790368 | ftsN | -0.2387 |
| cell division prt | g1786281 | ftsQ | -0.7429 |
| cell division prt | g1786277 | ftsW | 0.2459 |
| cell division membrane prt | g1789872 | ftsX | -0.2145 |
| cell division prt | g1789874 | ftsY | 0.4534 |
| cell division prt | g1786284 | ftsZ | 1.3791 |
| cell division protein ftsh EC3.4.24.- | g1789568 | hflB | 1.4165 |
| probable cell division role | g1787785 | hipA | -1.5776 |
| cell cycle protein | g1786386 | mesJ | -1.2041 |
| cell division inhibitor | g1787424 | minC | -0.8429 |
| cell division inhibitor | g1787423 | minD | -0.4056 |
| cell division topological specificity factor | g1787422 | minE | -0.559 |
| cell division inhibitor | g1787192 | sulA | -1.5768 |
4.3 Cell killing | | | | |
| KicA protein | g1787153 | mukE | 0.1561 |
| killing factor KicB | g1787152 | mukF | 0.2097 |
4.4 Chaperones | | | | |
| chaperone protein | g1786333 | ecpD | -1.3537 |
| heat shock prt | g1786197 | dnaJ | 0.9254 |
| heat shock prt 70 | g1786196 | dnaK | 2.3653 |
| chaperone protein involved in biogenesis of type 1 fimbriae | g1790771 | fimC | -1.6488 |
| heat shock protein; phage lambda replication; host DNA synthesis | g1788967 | grpE | 1.0982 |
| heat-responsive regulatory protein EC2.7.1.69 | g1786951 | hrsA | -0.7015 |
| heat shock prt C62.5 | g1786679 | htpG | 2.0808 |
| heat shock prt groEL | g1790586 | mopA | 3.1717 |
| heat shock prt groES | g1790585 | mopB | 1.1167 |
4.5 Detoxification | | | | |
| arsenate reductase (arsenical pump modifier) | g1789918 | arsC | -0.0457 |
| catalase HPII EC1.11.1.6 | g1788027 | katE | -0.1193 |
| catalase hydroperoxidase I EC1.11.1.6 | g1790378 | katG | 1.4895 |
| manganese superoxide dismutase EC1.15.1.1 | g1790342 | sodA | 2.3208 |
| superoxide dismutase EC1.15.1.1 | g1787946 | sodB | 1.1227 |
| copper-zinc superoxide dismutase EC1.15.1.1 | g1787934 | sodC | -0.2679 |
4.6 thiophene and furan oxidation | | g1790141 | thdF | 0.1083 |
4.7 Protein and peptide secretion | | | | |
| putative general secretion pathway protein b | g1789720 | yheD | -1.8865 |
| putative general secretion pathway protein c | g1789721 | yheE | -1.8458 |
| putative general secretion pathway protein d | g1789722 | yheF | -0.4857 |
| putative general secretion pathway protein e | g1789723 | yheG | -0.9802 |
| protein transport protein | g1786296 | hofB | -0.986 |
| protein transport protein | g1786295 | hofC | -1.0489 |
| protein transport protein hofq precursor | g1789793 | hofQ | -1.2848 |
| putative general secretion pathway protein f | g1789724 | hofF | -1.1891 |
| putative general secretion pathway protein g | g1789725 | hofG | -0.935 |
| putative general secretion pathway protein h | g1789726 | hofH | -1.6429 |
| putative general secretion pathway protein i | g1789727 | yheH | -1.1119 |
| putative general secretion pathway protein j | g1789728 | yheI | -1.6983 |
| putative general secretion pathway protein k | g1789729 | yheJ | -1.1943 |
| putative general secretion pathway protein l | g1789730 | yheK | -1.1704 |
| putative general secretion pathway protein m | g1789731 | pshM | -1.2298 |
| lpp signal peptidase EC3.4.23.36 | 3.4.23.36 | lspA | 0.0677 |
| peptide transport system ATP-BP | g1787547 | sapF | -0.6429 |
| preprotein translocase | g1790413 | secE | 0.534 |
| preprotein translocase secy subunit | g1789696 | prlA | 0.414 |
| protein-export membrane prt | g1786609 | secD | 1.0525 |
| protein-export membrane prt | g1786610 | secF | 0.7788 |
| protein-export membrane prt | g1789565 | secG | -0.0549 |
| protein-export prt | g1790038 | secB | 1.6859 |
| preprotein translocase sub | g1786287 | secA | 1.6357 |
| trigger factor | g1786640 | tig | 2.4251 |
5.Central intermediary metabolism | | | | |
5.1 Phosphorus compounds | | | | |
| inorganic PPase EC3.6.1.1 | g1790673 | ppa | 2.1357 |
| polyphosphate kinase EC2.7.4.1 | g1788847 | ppk | -0.0673 |
| lysophospholipase L2 EC3.1.1.5 | g1790259 | pldB | -0.7563 |
| exopolyphosphatase | ppx | 695 | -0.4786 |
5.2 Polysaccharides - (cytoplasmic) | | | | |
| glycogen Sase EC2.4.1.21 | g1789836 | glgA | -0.3207 |
| "1,4-glucan brancing enzyme EC2.4.1.18" | g1789839 | glgB | 0.1814 |
| ADP-glucose Sase EC1.7.7.27/EC2.7.7.27 | g1789837 | glgC | 0.6081 |
| a-glucan phosphorylase EC2.4.1.1 | g1789835 | glgP | 0.5145 |
| glycogen synthesis | g1789428 | glgS | -0.4316 |
| glycogen operon prt EC3.2.1.- | g1789838 | glgX | -0.8117 |
| alpha trehalose phosphate synthase EC2.4.1.15 | g1788206 | otsA | -0.5817 |
| trehalose phosphatase EC3.1.3.12 | g1788207 | otsB | -1.3073 |
| mannose-1-phosphate guanylyltransferase (gdp) | g1788362 | cpsB | 0.1487 |
| phosphomannomutase EC5.4.2.8 | g1788361 | cpsG | 0.1761 |
5.3 Sulfur metabolism | | | | |
| arylsulfatase regulatory prt EC3.1.6.1 | g1790233 | aslA | 0.4085 |
| arylsulfatase regulatory prt | g1790232 | aslB | -0.7344 |
5.4 Other Central. | | | | |
| (isocitrate dehydrogenase kinase/phosphatase EC 2.3.1.46 | g1790446 | aceK) | -0.2071 |
| 7-a-hydroxysteroid DHase EC1.1.1.159 | g1787905 | hdhA | -0.3138 |
| glucose dehydrogenase EC1.1.99.17 | g1786316 | gcd | 0.6803 |
| glyoxylate carboligase EC4.1.1.47 | g1786717 | gcl | 0.7519 |
| glycolate oxidase subunit | g1789351 | glcD | -0.0983 |
| glycolate oxidase subunits GlcE and GlcF | g1789350 | glcE/glcF | -0.6511 |
| "alanine racemase, catabolic precursor EC5.1.1.1" | g1787439 | dadX | -0.6997 |
| glycine acetyltransferase EC2.3.1.29 | g1790046 | kbl | 1.2037 |
| probable pyruvate formate-lyase 2 activating enzyme EC1.97.1.4 | g1790389 | pflC | -0.5788 |
| formate acetyltransferase 2 (pyruvate formate-II) EC2.3.1.54 | g1790388 | pflD | -0.1182 |
| threonine 3-dehydrogenase EC1.1.1.103 | g1790045 | tdh | 0.9217 |
| catabolic threonine dehydratase EC4.2.1.16 | g1789505 | tdcB | -0.2348 |
| tartrate dehydratse EC4.2.1.32 | g1789442 | ttdA | -0.3178 |
| tartrate dehydratse EC4.2.1.32 | g1789443 | ttdB | 0.9225 |
| putative l-serine dehydratase part 2 EC4.2.1.13 | g1789498 | yhaP | 0.5259 |
| putative l-serine dehydratase part 1 EC4.2.1.13 | g1789500 | yhaQ | -1.8684 |
| probable formate acetyltransferase 3 EC2.3.1.54 | g1789502 | yhaS | 0.7188 |
6. Energy metabolism | | | | |
6.1 Respiratory chain I (Dehydrogenases) | | | | |
| D-amino acid dehydrogenase | g1787438 | dadA | -0.1763 |
| D-lactate DHase EC1.1.1.28 (Aerobic) | g1788454 | dld | 0.2071 |
| DMSO RDase A (Anaerobic) | g1787121 | dmsA | 0.5339 |
| DMSO RDase B (Anaerobic) | g1787122 | dmsB | 0.6067 |
| DMSO RDase C (Anaerobic) | g1787123 | dmsC | -0.1666 |
| formate DHase-N affector | g1790329 | fdhD | -1.0755 |
| formate DHase pathway prt | g1790324 | fdhE | 0.4386 |
| formate dehydrogenase-H alpha subunit EC1.2.1.2 (Anaerobic) | g1790516 | fdhF | -0.5941 |
| formate DHase EC1.2.1.2 | g1787748 | fdnG | 1.0524 |
| gamma subunit of formate dehydrogenase N | g1787750 | fdnI | 0.5833 |
| beta subunit of formate dehydrogenase N | g1787749 | fdnH | 0.8884 |
| formate DHase-O a sub EC1.2.1.2 (Anaerobic) | g1790327 | fdoG | 0.5857 |
| formate DHase-O b sub EC1.2.1.2 (Anaerobic) | g1790326 | fdoH | 0.4848 |
| formate DHase-O g sub EC1.2.1.2 (Anaerobic) | g1790325 | fdoI | 0.4849 |
| "G3PD, sub A EC1.1.99.5 (Anaerobic)" | g1788574 | glpA | 0.2254 |
| "G3PD, sub B EC1.1.99.5 (Anaerobic)" | g1788575 | glpB | -0.5819 |
| "G3PD, sub C EC1.1.99.5 (Anaerobic)" | g1788576 | glpC | 0.0937 |
| glycerol-3-phosphate dehydrogenase EC1.1.99.5 (Aerobic) | g1789832 | glpD | 0.3674 |
| glycerol-3-P DHase EC1.1.1.8 (Aerobic) | g1790037 | gpsA | -0.4036 |
| hydrogenase-1 small chain EC1.18.99.1 | g1787206 | hyaA | -0.1085 |
| hydrogenase-1 large chain (nifE hydrogenase) EC1.18.99.1 | g1787207 | hyaB | 0.1839 |
| probable Ni/Fe-hydrogenase 1 b-type cytochrome | g1787208 | hyaC | 0.3621 |
| hydrogenase-2 small subunit EC1.18.99.1 (Aerobic) | g1789370 | hybA | 1.0786 |
| probable hydrogenase-2 cytochrome b subunit | g1789369 | hybB | 1.0316 |
| hydrogenase-2 large subunit EC1.18.99.1 (Aerobic) | g1789368 | hybC | 1.4382 |
| formate hydrogenlyase subunit 2 (Anaerobic) | g1789079 | hycB | 0.0455 |
| formate hydrogenlyase subunit 3 (Anaerobic) | g1789078 | hycC | -0.7866 |
| formate hydrogenlyase subunit 4 (Anaerobic) | g1789077 | hycD | 1.1128 |
| formate hydrogenlyase subunit 5 (Anaerobic) | g1789076 | hycE | -0.7834 |
| formate hydrogenlyase subunit 6 (Anaerobic) | g1789075 | hycF | 0.4995 |
| formate hydrogenlyase subunit 7 (Anaerobic) | g1789074 | hycG | 0.2963 |
| formate hydrogenlyase maturation protein | g1789073 | hycH | -0.1547 |
| hydrogenase isoenzymes formation protein | g1789082 | hypB | 0.321 |
| hydrogenase isoenzyme formation prt (Anaerobic) | g1789083 | hypC | -0.962 |
| hydrogenase isoenzymes formation protein | g1789084 | hypD | 0.1055 |
| hydrogenase isoenzymes formation protein HypE | g1789085 | hypE | 0.4903 |
| D-lactate dehydrogenase EC1.1.1.28 (Aerobic) | | ldhA | 0.9094 |
| NADH DHase EC1.6.99.3 (Aerobic) | g1787352 | ndh | 0.5756 |
| NADH dehydrogenase I chain A EC1.6.5.3 (Aerobic) | g1788625 | nuoA | 0.1772 |
| NADH dehydrogenase I chain B EC1.6.5.3 (Aerobic) | g1788624 | nuoB | 0.5664 |
| "NADH dehydrogenase I chain C,D EC1.6.5.3 (Aerobic)" | g1788622 | "nuoC,D" | 1.1972 |
| NADH dehydrogenase I chain E EC1.6.5.3 (Aerobic) | g1788621 | nuoE | 0.7651 |
| NADH dehydrogenase I chain F EC1.6.5.3 (Aerobic) | g1788620 | nuoF | 1.1821 |
| NADH dehydrogenase I chain H EC1.6.5.3 (Aerobic) | g1788618 | nuoH | 1.4786 |
| NADH dehydrogenase I chain J EC1.6.5.3 (Aerobic) | g1788616 | nuoJ | 0.786 |
| NADH dehydrogenase I chain L EC1.6.5.3 (Aerobic) | g1788614 | nuoL | 1.4758 |
| NADH dehydrogenase I chain M EC1.6.5.3 (Aerobic) | g1788613 | nuoM | 0.9225 |
| NADH dehydrogenase I chain N EC1.6.5.3 (Aerobic) | g1788612 | nuoN | 1.1361 |
| pyruvate dehydrogenase EC1.2.2.2 (Aerobic) | g1787096 | poxB | -0.451 |
"6.2 Respiratory chain II (Electron transport, Oxidases)" | | | | |
(cytochrome) | | | | |
| probable cytochrome oxidase subunit I EC1.10.3.- | g1787212 | appC | -0.1615 |
| probable cytochrome oxidase subunit II EC1.10.3.- | g1787213 | appB | -0.5628 |
| cytochromec-type prt | g1787230 | torC | -0.1136 |
| cytochrome c-type protein | g1788530 | napC | 0.6194 |
| cytochrome c-type protein | g1788531 | napB | 0.5111 |
| cytochrome b562 | g1790684 | cybC | -0.1414 |
| cytochrome oxidase sub I EC1.10.3.- | g1786953 | cydA | 1.0134 |
| cytochrome oxidase sub II EC1.10.3.- | g1786954 | cydB | 1.9042 |
| cytochrome o ubiquinol oxidase subunit II EC1.10.3.- | g1786635 | cyoA | 0.2729 |
| cytochrome o ubiquinol oxidase subunit I EC1.10.3.- | g1786634 | cyoB | 1.2577 |
| cytochrome o ubiquinol oxidase subunit III EC1.10.3.- | g1786633 | cyoC | 1.3835 |
| cytochrome o ubiquinol oxidase C subunit | g1786632 | cyoD | 0.815 |
| cytochrome o ubiquinol oxidase C subunit | g1786631 | cyoE | -0.299 |
(cytochrome c-type biogenesis) | | | | |
| cytochrome c-type biogenesis protein | g1788525 | ccmE | -0.0636 |
| cytochrome c-type biogenesis protein | g1788524 | ccmF | 0.283 |
| cytochrome c-type biogenesis protein | g1788522 | ccmH | -0.142 |
| cytochrome c-type biogenesis | g1790579 | cutA | -0.8424 |
| cytochrome c-type biogenesis protein | g1790511 | nrfE | -0.6836 |
| cytochrome c-type biogenesis protein | g1790512 | nrfF | -0.8441 |
(fumarate reductase) | | | | |
(nitrate reductase) | | | | |
| probable nitrate reductase ECEC1.7.99.4 (Anaerobic) | g1788534 | napA | 1.6828 |
| respiratory nitrate reductase 1 alpha chain EC1.7.99.4 (Anaerobic) | g1787477 | narG | 1.4795 |
| respiratory nitrate reductase 1 beta chain EC1.7.99.4 (Anaerobic) | g1787478 | narH | 1.7086 |
| respiratory nitrate reductase 1 delta chain EC1.7.99.4 (Anaerobic) | g1787479 | narJ | 0.3406 |
| respiratory nitrate reductase 1 gamma chain EC1.7.99.4 (Anaerobic) | g1787480 | narI | 1.4906 |
| respiratory nitrate reductase 2 gamma chain EC1.7.99.4 (Anaerobic) | g1787738 | narV | -0.5538 |
| respiratory nitrate reductase 2 delta chain EC1.7.99.4 (Anaerobic) | g1787739 | narW | -0.5833 |
| respiratory nitrate reductase 2 beta chain EC1.7.99.4 (Anaerobic) | g1787740 | narY | 0.3843 |
| respiratory nitrate reductase 2 alpha chain EC1.7.99.4 (Anaerobic) | g1787741 | narZ | 0.0611 |
| NADH-nitrate oxidoreductase apoprotein EC1.6.6.4 (Anaerobic) | g1789765 | nirB | 1.5157 |
| NADH-nitrate reductase activity EC1.6.6.4 (Anaerobic) | g1789767 | nirC | 1.1963 |
| nitrite reductase (nad(p)h) small subunit EC1.6.6.4 (Anaerobic) | g1789766 | nirD | 0.9599 |
| formate-dependent nitrite RDase (Anaerobic) | g1790506 | nrfA | 0.5868 |
| formate-dependent nitrite RDase (Anaerobic) | g1790507 | nrfB | -0.2299 |
| formate-dependent nitrite RDase prt Fe-S centers (Anaerobic) | g1790508 | nrfC | 0.025 |
| formate-dependent nitrite RDase transmembrane prt (Anaerobic) | g1790509 | nrfD | -0.0565 |
(TMANO reductase) | | | | |
| trimethylamine-N-oxide reductase EC1.6.6.9 | g1787231 | torA | 0.1686 |
(peroxidases) | | | | |
| thiol peroxidase | g1787584 | tpx | 1.7656 |
(Ferredoxin) | | | | |
| ferredoxin | g1788874 | fdx | 0.8491 |
| flavodoxin | g1786900 | fldA | 0.7201 |
| flavodoxin II | g1789262 | fldB | 0.3405 |
| ferredoxin--NADP reductase EC1.18.1.2 | g1790359 | fpr | -1.1956 |
| ferredoxin-type protein | g1788536 | napF | -0.5103 |
| ferredoxin-type protein | g1788532 | napH | -0.256 |
| ferredoxin-type protein | g1788533 | napG | -0.1707 |
(Others) | | | | |
| thiol:disulfide interchange protein | g1788523 | dsbE | -0.3907 |
| thiol:disulfide interchange protein (c-type cytochrome) | g1790578 | dsbD | -0.7894 |
| thiol:disulfide interchange protein | g1789260 | dsbC | -0.3185 |
| pyridine nucleotide transhydrogenase sub a EC1.6.1.1 | g1787887 | pntA | -0.1832 |
| pyridine nucleotide transhydrogenase sub b EC1.6.1.1 | g1787886 | pntB | 0.822 |
| probable cytochrome c peroxidase EC1.11.1.5 | g1789935 | yhjA | -0.7489 |
6.3 ATP-proton motive force interconversion | | | | |
| ATP Sase F1 a sub EC3.6.1.34 | g1790172 | atpA | 2.5668 |
| ATP Sase F0 a sub EC3.6.1.34 | g1790176 | atpB | 0.8371 |
| ATP Sase F1 e sub EC3.6.1.34 | g1790169 | atpC | 0.6746 |
| ATP Sase F1 b sub EC3.6.1.34 | g1790170 | atpD | 2.5965 |
| ATP Sase C chain | g1790175 | atpE | 1.6834 |
| ATP Sase F0 b sub EC3.6.1.34 | g1790174 | atpF | 0.8293 |
| ATP Sase F1 g sub EC3.6.1.34 | g1790171 | atpG | 1.2183 |
| ATP Sase F1 d sub EC3.6.1.34 | g1790173 | atpH | -0.1102 |
| ATP synthase subunit? | g1790177 | atpI | -0.9742 |
| | | | |
6.4 Catabolism of Carbohydrates (General) | | | | |
(Entner-Doudoroff) | | | | |
| 2-keto-3-deoxy-6-phosphogluconate 6-P aldolase EC4.1.2.14/EC4.1.3.16 | g1788156 | eda | 2.1997 |
| 6-phosphogluconate dehydratase EC4.2.1.12 | g1788157 | edd | 0.1283 |
(Gluconeogenesis) | | | | |
| phosphoenolpyruvate carboxykinase EC4.1.1.49 | g1789807 | pckA | 1.4847 |
(Glycolysis) | | | | |
| glucose-1-phosphatase precursor (g1pase) | g1787237 | agp | -0.0482 |
| enolase EC4.2.1.11 | g1789141 | eno | 3.2973 |
| fructose-bisphosphate aldolase EC4.1.2.13 | g1789293 | fba | 2.9202 |
| 1-phosphofructokinase EC2.7.1.56 | g1788493 | fruK | 0.1382 |
| glyceraldehyde 3-phosphate dehydrogenase A EC1.2.1.12 | g1788079 | gapA | 3.0829 |
| glyceraldehyde 3-phosphate dehydrogenase C EC1.2.1.12 | g1787686 | gapC | -0.0388 |
| glucose kinase EC2.7.1.2 | g1788732 | glk | -0.7148 |
| phosphoglyceromutase EC5.4.2.1 | g1786970 | gpmA | 1.687 |
| phosphoglucomutase EC5.4.2.2 | g1786904 | pgm | 1.6786 |
| phosphoglycerate kinase EC2.7.2.3 | g1789294 | pgk | 2.5845 |
| 6-phosphofructokinase EC2.7.1.11 | g1790350 | pfkA | 2.3873 |
| 6-phosphofructokinase isozyme EC2.7.1.11 | g1788017 | pfkB | -0.6438 |
| glucose-6-P isomerase EC5.3.1.9 | g1790457 | pgi | 1.6262 |
| pyruvate kinase type II EC2.7.1.40 | g1788160 | pykA | 0.7058 |
| pyruvate kinase EC2.7.1.40 | g1787965 | pykF | 2.2065 |
| triosephosphate isomerase EC5.3.1.1 | g1790353 | tpiA | 2.4897 |
| "putative 2,3-bisphosphoglycerate-independent phosphoglycerate " | g1790041 | yibO | 1.6066 |
(Pentose phosphate pathway) | | | | |
| 6-phosphogluconate DHase EC1.1.1.44 | g1788340 | gnd | 1.6413 |
| ribose 5-phosphate isomerase EC5.3.1.6 | g1789280 | rpiA | 0.8403 |
| transaldolase B EC2.2.1.2 | g1786189 | talB | 2.1603 |
| transaldolase-like protein EC2.2.1.- | g1790382 | talC | 0.2232 |
| transketolase 1 EC2.2.1.1 | g1789303 | tktA | 2.5055 |
| transketolase 2 EC2.2.1.1 | g1788808 | tktB | 0.0693 |
| glucose 6-phosphate 1 dehydrogenas EC1.1.1.49 | g1788158 | zwf | 0.6331 |
(TCA cycle) | | | | |
| (isocitrate lyase EC4.1.3.1 (Glyoxylate Bypass of TCA) | g1790445 | aceA) | 1.268 |
| (malate synthase A EC4.1.3.2 (Glyoxylate Bypass of TCA) | g1790444 | aceB) | -0.3062 |
| pyruvate DHase EC1.2.4.1 | g1786304 | aceE | 2.4506 |
| dihydrolipoamide acetyltransferase EC2.3.1.12 | g1786305 | aceF | 2.1666 |
| "aconitate hydratase 1 (citrate hydro-lyase 1) EC4.2.1.3 (Anaerobic, Aerobic)" | g1787531 | acnA | -0.4348 |
| malate synthase EC4.1.3.2 (Glyoxylate Bypass of TCA) | g1789348 | glcB | 0.3605 |
| "citrate synthetase (Aerobic, Anaerobic)" | g1786939 | gltA | 1.6826 |
| fumarate RDase 13kD hydrophobic prt EC1.3.99.1 (Anaerobic) | g1790594 | frdD | 0.8026 |
| fumarate RDase flavoprotein sub EC1.3.99.1 (Anaerobic) | g1790597 | frdA | 1.6567 |
| fumarate RDase iron-sulfur prt EC1.3.99.1 (Anaerobic) | g1790596 | frdB | 1.2217 |
| fumarate RDase EC1.3.99.1 (Anaerobic) | g1790595 | frdC | 0.2821 |
| fumarate hydratase class i (fumarase) EC4.2.1.2 (Anaerobic) | g1790564 | fumB | 0.9039 |
| isocitrate dehydrogenase EC1.1.1.42 | g1787381 | icdA | 1.7643 |
| lipoamide DHase EC1.8.1.4 | g1786307 | lpdA | 2.4327 |
| phosphoenol pyruvate carboxylase EC4.1.1.31 (Glycerate bypass of TCA) | g1790393 | ppc | 0.6118 |
| succinate dehydrogenase flavoprotein subunit EC1.3.99.1 (Aerobic) | g1786942 | sdhA | 1.5892 |
| succinate dehydrogenase iron-sulfur protein EC1.3.99.1 (Aerobic) | g1786943 | sdhB | -0.3058 |
| succinate dehydrogenase cytochrome b-556 subunit (Aerobic) | g1786940 | sdhC | -1.0176 |
| succinate dehydrogenase 13 kD hydrophobic protein (Aerobic) | g1786941 | sdhD | 0.3942 |
| NAD-linked malic enzyme; malate oxidoreductase EC1.1.1.38 | g1787754 | sfcA | 0.2308 |
| 2-oxoglutarate DHase EC1.2.4.2 (Aerobic) | g1786945 | sucA | 1.4356 |
| dihydrolipoamide succinyltransferase (Aerobic) | g1786946 | sucB | 2.0848 |
| "succinyl-CoA Sase b sub EC6.2.1.5 (Aerobic, Anaerobic)" | g1786948 | sucC | 1.4043 |
| "succinyl-CoA Sase a sub EC6.2.1.5 (Aerobic, Anaerobic)" | g1786949 | sucD | 2.2288 |
| "fumarate hydratase class I"" EC4.2.1.2 (Aerobic)" | g1787897 | fumA | 0.1486 |
| fumarate hydratase EC4.2.1.2 (Aerobic) | g1787896 | fumC | -0.2077 |
| "malate DHase EC1.1.1.37 (Aerobic, Anaerobic)" | g1789632 | mdh | 1.7353 |
(Terminal reaction of Glycolysis: pyrumate and acetyl-CoA metabolism for Synechocystis) | | | | |
| acetate kinase EC2.7.2.1 (Anaerobic > Aerobic) | g1788633 | ackA | 2.0209 |
| acetyl-CoA sythetase EC6.2.1.1 | g1790505 | acs | 0.9457 |
| alcohol/acetaldehyde dehydrogenase EC1.1.1.1 | g1787493 | adhE | 2.1504 |
| formate acetyltransferase 1 EC2.3.1.54 (Anaerobic > Aerobic) | g1787131 | pflB | 3.0429 |
| phosphoenolpyruvate synthase EC2.7.9.2 | g1787994 | ppsA | 0.9979 |
| phosphate acetyltransferase EC2.3.1.8 (Anaerobic > Aerobic) | g1788635 | pta | 2.5013 |
6.5 Catabolism of Carbohydrates (Specific) | | | | |
(Amino sugars) | | | | |
| Gln amidotransferase (C) | g1790167 | glmS | 1.537 |
| GlcAc-6-P deacetylase EC3.5.1.25 (C) | g1786892 | nagA | 0.5449 |
| glucosamine-6-P deaminase EC5.3.1.10 (C) | g1786893 | nagB | 1.2947 |
| putative galactosamine-6-phosphate isomerase EC5.3.1.- | g1789530 | yhbU | -0.0186 |
(Carboxylates) | | | | |
| tagatose-bisphosphate aldolase | g1789526 | agaY | -0.1824 |
| putative tagatose 6-phosphate kinase agaz EC2.7.1.- | g1789520 | agaZ | 0.3096 |
| aldehyde DHase EC1.2.1.3 (C) | g1787558 | aldH | 0.2994 |
| L-arabinose isomerase EC5.3.1.4 (C) | g1786248 | araA | 1.1773 |
| l-ribulokinase EC2.7.1.16 (C) | g1786249 | araB | 0.2142 |
| L-ribulose-P 4-epimerase EC5.1.3.4 (C) | g1786247 | araD | 0.0734 |
| 6-phospho-beta-glucosidase EC3.2.1.86 | g1789070 | ascB | 0.2057 |
| phospho-beta-glucosidase EC3.2.1.86 (C) | g1790158 | bglB | -1.414 |
| phospho-beta-glucosidase B EC3.2.1.86 | g1788029 | celF | -0.3231 |
| phospho-beta-D-galactosidase; alpha-subunit | g1789457 | ebgA | 0.4426 |
| "phospho-beta-D-galactosidase, beta-subunit" | g1789458 | ebgC | -0.8228 |
| fucolose-1-P aldolase EC4.1.2.17 (C) | g1789164 | fucA | -0.9194 |
| fucokinase EC2.7.1.51 (C) | g1789168 | fucK | -1.0777 |
| "1,2-propanediol oxidoreductase (lactaldehyde reductase) EC1.1.1.77 (C)" | g1789163 | fucO | -0.1103 |
| UDP-Glc 4-epimerase EC5.1.3.2 (C) | g1786974 | galE | 0.3346 |
| UTP-glucose-1-phosphate uridylyltransferase EC2.7.7.9 | g1788355 | galF | 0.3464 |
| galactokinase EC2.7.1.6 (C) | g1786972 | galK | 0.4991 |
| aldose 1-epimerase (mutarotase) EC5.1.3.3 | g1786971 | galM | 0.3595 |
| Gal-1-P uridylyltransferase EC2.7.7.10 (C) | g1786973 | galT | -0.1294 |
| Glc-P uridylyltransferase EC2.7.7.9 (C) | g1787488 | galU | 0.0031 |
| galactitol-1-phosphate dehydrogenase EC1.1.1.- (C) | g1788407 | gatD | -1.3004 |
| tagatose-bisphosphate aldolase EC4.1.2.- | g1788412 | gatY | -0.905 |
| putative tagatose 6-phosphate kinase EC2.7.1.- | g1788411 | gatZ | -1.039 |
| glycerol kinase EC2.7.1.30 (C) | g1790361 | glpK | 0.9521 |
| glycerophosphoryl diester phosphodiesterase | g1788572 | glpQ | -0.3809 |
| probable 6-phospho-beta-glucosidase EC3.2.1.86 | g1790115 | glvG | 0.2168 |
| gluconate kinase EC2.7.1.12 | g1790719 | gntV | -2.2986 |
| L-fucose isomerase EC5.3.1. (C)- | g1789167 | fucI | 0.4059 |
| 2-keto-3-deoxy-D-gluconate kinase EC2.7.1.45 (C) | g1789945 | kdgK | 0.3332 |
| 2-keto-3-deoxygluconate oxydoreductase EC1.1.1.125 | g1789208 | kduD | -0.0699 |
| thiogalactoside acetyltransferase EC2.3.1.18 (C) | g1786537 | lacA | -1.7811 |
| beta-galactosidase (C) | g1786539 | lacZ | -0.2034 |
| cryptic l-xylulose kinase (l-xylulokinase) EC2.7.1.53 | g1790005 | lyxK | 0.0411 |
| mannose-6-phosphate isomerase EC5.3.1.8 | g1787899 | manA | 0.2115 |
| maltodextrin phosphorylase EC2.4.1.1 (C) | g1789822 | malP | 0.5123 |
| 4-alpha-glucanotransferase EC2.4.1.25 (C) | g1789821 | malQ | -0.2547 |
| alpha-amylase EC3.2.1.1 | g1789995 | malS | -0.8737 |
| mal inducer biosyn blocker EC2.6.1.- (C) | g1787909 | malY | -0.5285 |
| maltodextrin glucosidase EC3.2.1.20 | g1786604 | malZ | -0.5675 |
| alpha-galactosidase EC3.2.1.22 | g1790560 | melA | -0.2116 |
| mannitol-1-phosphate dehydrogenase EC1.1.1.17 (C) | g1790028 | mtlD | 0.7469 |
| N-acetylneuraminate lyase EC4.1.3.3 | g1789620 | nanA | 0.2353 |
| ribokinase (C) | g1790193 | rbsK | -0.7441 |
| L-rhamnose isomerase EC5.3.1.14 (C) | g1790337 | rhaA | 0.0776 |
| rhamnulose kinase (C) | g1790338 | rhaB | -0.6631 |
| rhamnulose-1-phosphate aldolase EC4.1.2.19 (C) | g1790336 | rhaD | -0.1506 |
| glucitol-6-phosphate dehydrogenase EC1.1.1.140 | g1789057 | srlD | 0.4612 |
| periplasmic trehalase | g1787447 | treA | -0.7986 |
| probable cytoplasmic trehalase (C) | g1789936 | treF | 0.1666 |
| trehalose-6-phosphate hydrolase EC3.2.1.93 (C) | g1790687 | treC | -0.6624 |
| beta-D-glucuronidase EC3.2.1.31 (C) | g1787903 | uidA | 0.1935 |
| 5'-nucleotidease=UDP-sugar hydrolase precursor EC3.6.1.45 | g1786687 | ushA | 0.0087 |
| altronate oxidoreductase EC1.1.1.58 (C) | g1787800 | uxaB | 1.0154 |
| D-mannonate hydrolase EC4.2.1.8 (C) | g1790778 | uxuA | 1.9521 |
| D-mannonate oxidoreductase EC1.1.1.57 (C) | g1790779 | uxuB | 1.3956 |
| xylosse isomerase EC5.3.1.5 (C) | g1789988 | xylA | 0.3465 |
| xylulose kinase EC2.7.1.17 (C) | g1789987 | xylB | -0.99 |
(pentoses in nucleosides and deoxynucleosides) | | | | |
| xanthosine phosphorylase EC2.4.2 (C)- | g1788746 | xapA | -0.2383 |
| phosphopentomutase EC2.7.5.6/EC5.4.2.7 (C)- | g1790843 | deoB | 2.2282 |
| deoxyribose aldolase EC4.1.2.4 (C) | g1790841 | deoC | 2.0214 |
(fatty acid degradation: FFF) | | | | |
| beta sub of the fatty acid-oxidizing multi enzyme complex EC2.3.1.16 (C) | g1790280 | fadA | -1.6357 |
| alpha sub of the fatty acid-oxidizingmultienzymecomplex (C) | g1790281 | fadB | 0.78 |
| long chain acyl-CoA synthetase EC6.2.1.3 (C) | g1788107 | fadD | 0.0442 |
6.6 Amino acids and amines | | | | |
| L-asparaginase II EC3.5.1.1 | g1789327 | ansB | 1.6106 |
| "aspartase EC4.3.1.1 (TCA, Anaerobic)" | g1790581 | aspA | 1.679 |
| lysine decarboxylase EC4.1.1.18 | g1790573 | cadA | 1.7141 |
| carbamoyl-phosphate synthase small chain EC6.3.5.5 | g1786215 | carA | 0.3059 |
| carbamoyl-phosphate synthase large chain EC6.3.5.5 | g1786216 | carB | 1.8038 |
| succinate-semialdehyde dehydrogenase EC1.2.1.16 | g1789015 | gabD | 0.3182 |
| glutamate decarboxylase alpha EC4.1.1.15 | g1789934 | gadA | 1.0591 |
| glutamate decarboxylase-beta EC4.1.1.15 | g1787769 | gadB | 1.1099 |
| glycine cleavage system H protein | g1789271 | gcvH | 1.5563 |
| glycine dehydrogenase (decarboxylating) EC 1.4.4.2 | g1789269 | gcvP | 0.9896 |
| aminomethyltransferase EC2.1.2.10 | g1789272 | gcvT | 0.5238 |
| delta-1-pyrroline- 5-carboxylate dehydrogenase EC1.5.99.8 | g1787250 | putA | 0.2148 |
| L-Ser deaminase EC4.2.1.13 | g1788116 | sdaA | 0.6766 |
7.Fatty acid and phospholipid metabolism | | | | |
| 2-acylglycerophosphoethanolamine acyl transferase/acyl carrier protein synthetase | g1789201 | aas | -0.5214 |
| Ac-CoA carboxylase EC6.4.1.2 | g1786382 | accA | 1.0046 |
| biotin carboxyl carrier prt EC6.4.1.2 | g1789653 | accB | 1.9984 |
| biotin carboxylase EC6.3.4.14 | g1789654 | accC | 1.3911 |
| acetyl-CoA carboxylase beta subunit EC6.4.1.2 | g1788655 | accD | 0.9315 |
| acyl carrier protein phosphodiesterase | g1787680 | acpD | 0.8721 |
| acyl carrier prt | g1787336 | acpP | 1.5906 |
| | g1788916 | acpS | -1.1522 |
| CDP-diglyceride hydrolase EC3.6.1.26 | g1790352 | cdh | -1.371 |
| CDP-diglyceride Sase EC2.7.7.41 | g1786372 | cdsA | -0.7052 |
| cyclopropane-fatty-acyl-phospholipid synthase EC2.1.1.79 | g1787951 | cfa | -0.5548 |
| cardiolipin synthetase EC2.7.8.- | g1787502 | cls | -1.1035 |
| diacylglycerol kinase EC2.7.1.107 | g1790475 | dgkA | -0.5193 |
| D-3-hydroxydecanoyl-(acyl carrier-protein) EC 4.2.1.60 | g1787187 | fabA | 1.6101 |
| b-ketoacyl-ACP Sase I EC2.3.1.41 | g1788663 | fabB | 2.1543 |
| malonyl CoA acyl carrier prt transacylase EC2.3.1.39 | g1787334 | fabD | 0.6859 |
| 3-oxoacyl-[acyl-carrier-protein] synthase II EC2.3.1.41 | g1787337 | fabF | 0.7815 |
| 3-ketoacyl-acyl carrier prt RDase EC1.1.1.100 | g1787335 | fabG | 0.3145 |
| b-ketoacyl-acyl carrier prt Sase III EC2.3.1.41 | g1787333 | fabH | 0.2246 |
| enoyl-[acyl-carrier-protein] reductase (NADH) EC1.3.1.9 | g1787545 | fabI | 1.7521 |
| (3R)-hydroxymyristol acyl carrier prt dehydrase | g1786377 | fabZ | 0.424 |
| fatty acid metabolism prt = fatty acid--fatty acyl responsive DNA-binding protein | g1787436 | fadR | -0.4254 |
| glycerol dehydrogenase EC1.1.1.6 | g1790381 | gldA | 0.7864 |
| UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase EC2.3.1.- | g1786376 | lpxD | -0.081 |
| phosphatidylglycerophosphate phosphatase B EC3.1.3.27 | g1787534 | pgpB | -1.783 |
| phosphatidylglycerophosphate Sase EC2.7.8.5 | g1788220 | pgsA | -0.5361 |
| detergent-resistant phospholipase A EC3.1.1.32 | g1790255 | pldA | 0.1314 |
| glycerol-3-P acyltransferase EC2.3.1.15 | g1790474 | plsB | 0.3008 |
| 1-acyl-glycerol-3-P acyltransferase EC2.3.1.51 | g1789395 | plsC | 0.0016 |
| probably fatty acid or phospholipid synthesis | g1787331 | plsX | -1.8019 |
| phosphatidylserine DCase proenzyme EC4.1.1.65 | g1790604 | psd | 0.6537 |
| acyl-coA thioesterase I EC3.1.2 | g1786702 | tesA | -0.7689 |
| acyl-CoA thioesterase II EC3.1.2.- | g1786657 | tesB | -0.2508 |
| USG-1 prt | g1788658 | usg | 0.7346 |
"8.Purines, pyrimidines, nucleotides, and nucleotides" | | | | |
8.1 2'-Deoxyribonucleotide metabolism (deoxyribonucleotide metabolism) | | | | |
| deoxycytidine triphosphate deaminase EC3.5.4.13 | g1788379 | dcd | 0.7155 |
| deoxyuridinetriphosphatase EC3.6.1.23 | g1790071 | dut | 0.6423 |
| ribonucleoside diphosphate RDase 1 a chain EC1.17.4.1 | g1788566 | nrdA | 1.7266 |
| ribonucleoside diphosphate RDase b2 sub EC1.17.4.1 | g1788567 | nrdB | 1.2272 |
| anaerobic ribonucleoside-triphosphate RDase EC1.17.4.2 | g1790686 | nrdD | 1.1625 |
| ribonucleoside-diphosphate reductase 2 alpha EC1.17.4.1 | g1789030 | nrdE | -0.3675 |
| ribonucleoside-diphosphate reductase 2 beta EC1.17.4.1 | g1789031 | nrdF | -0.3663 |
| thioredoxin RDase EC1.6.4.5 | g1787114 | trxB | 0.4554 |
| thymidylate Sase EC2.1.1.45 | g1789191 | thyA | 0.716 |
8.2 Purine ribonucleotide biosynthesis | | | | |
| adenylate kinase EC2.7.4.3 (de nova) | g1786680 | adk | 2.2402 |
| GMP reductase EC1.6.6.8 | g1786293 | guaC | 0.6066 |
| 5'-guanylate kinase (de nova) | g1790080 | gmk | -0.5364 |
| adenylosuccinate Sase EC6.3.4.4 (de nova) | g1790620 | purA | 2.2316 |
| adenylosuccinate lyase EC4.3.2.2 (de nova) | g1787376 | purB | 1.202 |
| phosphoribosylamine-Gly ligase EC6.3.4.13 (de nova) | g1790438 | purD | 0.8526 |
| phosphoribosylaminoimidazole carboxylase catalytic sub (de nova) | g1786734 | purE | 0.9201 |
| amidoPRTase EC2.4.2.14 (de nova) | g1788651 | purF | 0.693 |
| EC2.1.2.3/EC3.5.4.10 (de nova) | g1790439 | purH | 1.2295 |
| 5'-phosphoribosyl-5-amino-4-imidazole carboxylase II EC4.1.1.21 | g1786733 | purK | 0.222 |
| phosphoribosylglycinamide formyltransferase 2 EC2.1.2.- | g1788155 | purT | -0.6367 |
| formyltetrahydrofolate hydrolase EC3.5.1.10 | g1787483 | purU | -0.2341 |
| phosphoribosylpyrophosphate Sase EC2.7.6.1 | g1787458 | prsA | 1.7213 |
(Purine salvage) | | | | |
| adenosine deaminase EC3.5.4.4 (C) | g1787910 | add | -0.2476 |
| AMP nucleosidase EC3.2.2.4 | g1788293 | amn | -1.1523 |
| adenine PRTase EC2.4.2.7 | g1786675 | apt | 1.4054 |
| purine-nucleoside phosphorylase EC2.4.2.1 (C)- | g1790844 | deoD | 2.072 |
| xanthine-guanine phosphoribosyltransferase EC2.4.2.22 | g1786433 | gpt | 1.2523 |
| hypoxanthine phosphoribosyltransferase EC2.4.2.8 | g1786317 | hpt | 1.4894 |
8.3 Pyrimidine ribonucleotide biosynthesis | | | | |
| aspartate carbomoyltransferase catalytic subunit EC2.1.3.2 (de nova) | g1790693 | pyrB | -1.9161 |
| dihydroorotase EC3.5.2.3 (de nova) | g1787301 | pyrC | -0.2031 |
| dihydroorotate DHase EC1.3.3.1 (de nova) | g1787177 | pyrD | -0.7513 |
| orotate PRTase (de nova) | g1790073 | pyrE | 0.0163 |
| orotidine-5'-monophosphate DCase EC4.1.1.23 (de nova) | g1787537 | pyrF | -0.5971 |
| CTP Sase EC6.3.4.2 (de nova) | g1789142 | pyrG | 1.0993 |
| uridine 5'-monophosphate kinase EC2.7.4. (de nova)- | g1786367 | pyrH | 1.1536 |
| aspartate carbomoyltransferase regulatory EC2.1.3.2 (de nova) | g1790692 | pyrI | -0.3149 |
(Pyrimidine salvage) | | | | |
| cytidine deaminase EC3.5.4.5 (C) | g1788465 | cdd | -0.0071 |
| cytosine deaminase EC3.5.4.1 | g1786531 | codA | -0.0826 |
| thymidine phosphorylase EC2.4.2.4 (C)- | g1790842 | deoA | 1.1475 |
| thymidine kinase EC2.7.1.21 | g1787490 | tdk | -1.7246 |
| uridine phosphorylase EC2.4.2.3 (C) | g1790265 | udp | 1.6736 |
8.4 Nucleotide and nucleoside interconversions | | | | |
| dGTP triphosphohydrolase EC3.1.5.1 | g1786355 | dgt | -1.1039 |
| uridine kinase EC2.7.1.48 | g1788380 | udk | -0.2496 |
| probable adenine deaminase EC3.5.4.2 | g1790098 | yicP | -0.6372 |
(Others) | | | | |
| adenosine tetraphosphatase=bis(5'-nucleosyl)-tetraphosphatase EC3.6.1.41 | g1786234 | apaH | 0.1297 |
| cytidylate kinase EC2.7.4.14 | g1787139 | cmk | -1.0005 |
| "2',3'-cyclic nucleotide 2'-phosphodiesterase EC3.1.4.16" | g1790658 | cpdB | -0.2297 |
| inosine-guanosine kinase EC2.7.1.73 | g1786684 | gsk | 0.423 |
| putative ATPase | g1788431 | mrp | 0.06 |
9.Regulatory functions | | | | |
| ADA regulatory protein EC2.1.1.63 | g1788542 | ada | -0.6692 |
| potential acrAB operon repressor | g1786669 | acrR | -1.4978 |
| arsenical resistance operon arsefg repressor | g1789916 | arsR | -0.676 |
| sensor protein EC2.7.3.- | g1788549 | atoS | -1.0596 |
| putative aga operon transcriptional repressor | g1789519 | agaR | -0.2918 |
| putative regulatory protein | g1790557 | adiY | -1.5981 |
| positive regulator of int transcription | g1788977 | alpA | -2.7725 |
| arabinose operon regulatory protein | g1786251 | araC | -0.9003 |
| aerobic respiration control prt | g1790863 | arcA | 1.103 |
| aerobic respiration control sensor prt EC2.7.3.- | g1789603 | arcB | 0.0006 |
| Arg repressor prt | g1789633 | argR | -0.6109 |
| asc operon repressor protein | g1789068 | ascG | -0.8422 |
| regulatory prt | g1790182 | asnC | 0.1975 |
| acetoacetate metabolism regulatory protein | g1788550 | atoC | -1.0002 |
| transcriptional regulatory protein | g1788394 | baeR | -0.0127 |
| sensor protein BaeS EC2.7.3.- | g1788393 | baeS | -0.4794 |
| bacterial adaptive response EC2.7.3.- | g1789149 | barA | -0.739 |
| transcriptional regulatory prt | g1790552 | basR | -0.7351 |
| sensor prt for basR EC2.7.3.- | g1790551 | basS | -0.7847 |
| regulatory protein | g1786505 | betI | -0.3053 |
| positive regulatory protein; cryptic beta-glucoside bgl operon antiterminator | g1790160 | bglG | -1.8498 |
| putative murein gene regulator | g1786638 | bolA | -1.0193 |
| cation transport regulator | g1787469 | chaB | 0.0291 |
| transcriptional activator cadc | g1790576 | cadC | -1.3799 |
| cel operon repressor | g1788030 | celD | -1.4353 |
| curlin genes transcriptional activator | g1786435 | crl | 0.8584 |
| chemosensory transducer EC2.7.3.- | g1790346 | cpxA | 0.3193 |
| transcriptional regulatory protein cpxr | g1790347 | cpxR | -1.3605 |
| catabolic regulation; transcriptional regulatory protein | g1790860 | creB | -1.1628 |
| positive regulatory gene for pho regulon EC2.7.3.-; sensor protein crec | g1790861 | creC | -0.9954 |
| transcriptional regulator | g1786838 | criR | -1.218 |
| necessary for transcription of the csgBA operon | g1787277 | csgD | -1.1636 |
| adenylate cyclase | g1790238 | cyaA | 0.1787 |
| cys regulon transcription activator | g1787530 | cysB | -0.8591 |
| regulation of deo operon; transcriptional repressor | g1790369 | cytR | -0.2952 |
| cyn operon transcriptional activator | g1786533 | cynR | -1.6826 |
| cyclic AMP receptor protein | g1789756 | crp | 1.1717 |
| carbon storage regulator | g1789047 | csrA | 1.167 |
| repressor protein of division inhibition gene dicB | g1787853 | dicA | -1.8568 |
| repressor protein of division inhibition gene dicB | g1787852 | dicC | -1.7657 |
| deoxyribose operon repressor | g1787063 | deoR | -0.7324 |
| regulatory protein | g1786405 | dniR | -0.3541 |
| d-serine deaminase activator | g1788706 | dsdC | -1.1636 |
| ebg repressor | g1789456 | ebgR | -0.3634 |
| potential acref/envcd operon repressor | g1789664 | envR | -1.918 |
| osmolarity sensor EC2.7.3.- | g1789808 | envZ | -0.121 |
| putative sensor protein EC2.7.3.- | g1788713 | evgS | -1.746 |
| putative positive transcription regulator | g1788712 | evgA | -2.1016 |
| exu regulon regulator | g1789480 | exuR | 0.1667 |
| fatty acyl responsive regulator (p30 protein) | g1786950 | farR | -1.0537 |
| probable RNA polymerase sigma factor feci | g1790746 | fecI | -0.5765 |
| transcriptional activator of the formate hydrogen lyasesystem | g1789087 | fhlA | -0.2296 |
| regulatory gene for expression of fimA;recombinase involved in phase variation | g1790767 | fimB | -1.5463 |
| regulatory gene for expression of fimA;recombinase involved in phase variation | g1790768 | fimE | -1.4956 |
| negative regulator of flagellin synthesis (anti-sigmafactor) | g1787311 | flgM | -0.3783 |
| flagellar transcriptional activator | g1788201 | flhC | -0.6406 |
| flagellar transcriptional activator | g1788202 | flhD | -0.7382 |
| RNA polymerase sigma transcription factor for flagellar operon | g1788231 | fliA | -0.5181 |
| putative frv operon regulatory protein | g1790331 | frvR | -1.0468 |
| fumarate (and nitrate) reduction regulatory prt | g1787595 | fnr | 0.5446 |
| fructose repressor | g1786268 | fruR | -0.2406 |
| L-fucose operon activator | g1789170 | fucR | -1.1204 |
| ferric uptake regulation prt | g1786899 | fur | 0.0351 |
| repressor of galETK operon | g1789202 | galR | -0.2112 |
| galactose operon repressor | g1788474 | galS | -0.4241 |
| repressor of the gat operon | g1788406 | gatR | -1.7053 |
| Gly cleavage system transcriptional activator | g1789173 | gcvA | -1.1947 |
| glc operon transcriptional activator | g1789353 | glcC | -0.6247 |
| uridylyl Tase EC2.7.7.59 | g1786363 | glnD | -0.6983 |
| negative regulation of glnA | g1790299 | glnG | -0.2252 |
| glutamine synthetase activity regulation; nitrogen regulatory protein P-II | g1786655 | glnK | 0.3256 |
| negative regulation of glnA EC2.7.3.- | g1790300 | glnL | -0.511 |
| egative regulatory protein of glp regulon | g1789830 | glpG | -0.4713 |
| glycerol-3-P regulon repressor | g1789829 | glpR | 0.0363 |
| regulatory protein | g1789608 | gltF | -0.8893 |
| gtnUKR operon regulator | g1789846 | gntR | -0.1533 |
| glucuronide repressor | g1787904 | gusR | -0.8713 |
| glucitol operon activator | g1789058 | gutM | -0.7021 |
| GTP-binding protein hflx | g1790615 | hflX | 0.0814 |
| repressor of the hip operon | g1787786 | hipB | -1.6312 |
| formate hydrogenlyase regulatory protein | g1789080 | hycA | -0.2187 |
| hydrogenase activity | g1790436 | hydH | -1.0699 |
| transcriptional regulatory protein | g1790437 | hydG | -0.3337 |
| lacZ expression regulator | g1789410 | icc | 0.0172 |
| regulatory gene for aceBAK operon | g1790449 | iclR | -0.9154 |
| transcriptional activator prt | g1790208 | ilvY | -0.5487 |
| sensor protein KdpD EC2.7.3.- | g1786912 | kdpD | -0.7647 |
| lactose operon repressor | g1786540 | lacI | -0.5434 |
| probable activator protein in leuABCD operon | g1786264 | leuO | -1.3879 |
| LexA repressor | g1790476 | lexA | -0.056 |
| NADH dehydrogenase operon transcriptional regulator | g1788626 | lrhA | -0.4916 |
| Leu responsive regulatory prt | g1787116 | lrp | -0.5571 |
| positive regulatory gene | g1789204 | lysR | -0.9506 |
| regulatory gene | g1786976 | modE | -0.519 |
| regulatory gene for mar | g1787812 | marB | -2.183 |
| repressor protein | g1787906 | malI | -1.3512 |
| positive regulatory gene for mal regulon | g1789824 | malT | -0.107 |
| regulatory gene | g1790559 | melR | -0.5423 |
| metF aporepressor | g1790373 | metJ | 0.2979 |
| trans-activator of metE and metH | g1790262 | metR | -0.9622 |
| molybdate metabolism regulator | g1788433 | molR | -1.7178 |
| multicopy suppressor of htrB | g1788161 | msbB | -0.6971 |
| acidic protein MsyB; multicopy suppressor of SecY | g1787289 | msyB | -1.9175 |
| mannitol operon repressor | g1790029 | mtlR | -0.2041 |
| nitrogen assimilation control protein | g1788297 | nac | -1.8736 |
| nadAB transcriptional regulator | g1790851 | nadR | -0.1099 |
| "nitrate, nitrite response regulator prt" | g1788521 | narP | -0.6825 |
| nitrate/nitrite response regulator protein | g1787473 | narL | -0.3693 |
| nitrate/nitrite sensor protein EC2.7.3.- | g1787474 | narX | -0.7427 |
| transcriptional activator protein nhaR | g1786202 | nhaR | -1.1289 |
| anaerobic ribonucleoside-triphosphate reductase activating pr | g1790685 | nrdG | -0.1882 |
| regulatory protein RecX | g1789050 | oraA | -0.806 |
| hydrogen peroxide-inducible activator | g1790399 | oxyR | 0.1631 |
| positive regulatory gene for ompC and ompF | g1789809 | ompR | 0.7909 |
| pyruvate dehydrogenase complex repressor | g1786303 | pdhR | -0.2104 |
| pyruvate formate-lyase 1 activating enzyme EC1.97.1.4 | g1787130 | pflA | 0.5301 |
| transcriptional regulatory protein | g1787375 | phoP | -0.6883 |
| sensor protein EC2.7.3.- | g1787374 | phoQ | -1.0017 |
| phosphate regulon sensor prt EC2.7.3.- | g1786600 | phoR | -0.4806 |
| phosphate regulon transcriptional regulatory prt | g1786599 | phoB | -0.7802 |
| purine nucleotide synthesis repressor prt | g1787947 | purR | 0.4449 |
| rbs repressor | g1790194 | rbsR | -0.6959 |
| regulator of capsule synthesis B component | g1788546 | rcsB | 0.0539 |
| sensor protein RcsC EC2.7.3.- | g1788548 | rcsC | -0.8418 |
| stimulates colanic acid capsule synthesis | g1786394 | rcsF | -0.877 |
| l-rhamnose operon transcriptional activator rhaR | g1790340 | rhaR | -1.065 |
| l-rhamnose operon regulatory protein rha | g1790339 | rhaS | -1.2275 |
| ATP:GTP 3'-pyrophosphotransferase EC2.7.6.5 | g1789147 | relA | 0.316 |
| "transcriptional activator of lipopolysacharide, sex factor and haemolysin genes" | g1790276 | rfaH | -0.7232 |
| regulator of nucleoside diphosphate kinase | g1786827 | rnk | -0.112 |
| sigma-E factor negative regulatory protein | g1788925 | rseA | -0.4819 |
| sigma-E factor regulatory protein | g1788924 | rseB | -0.9885 |
| sigma-E factor regulatory protein | g1788923 | rseC | -1.0121 |
| suppresses ftsI mutation | g1789394 | sufI | -0.3052 |
| regulatory protein | g1788224 | sdiA | -1.2516 |
| ftsH suppressor protein | g1788946 | sfhB | 0.0824 |
| htrA suppressor protein | g1789517 | sohA | -0.3241 |
| regulation of superoxide response regulon | g1790498 | soxR | -1.0958 |
| regulation of superoxide response regulon | g1790497 | soxS | -0.6303 |
| glucitol operon repressor | g1789059 | srlR | -0.3896 |
| penta-P guanosine-3'-pyrophosphohydrolase | g1790082 | spoT | 0.2427 |
| stringent starvation prt A | g1789624 | sspA | 1.3023 |
| stringent starvation prt B | g1789623 | sspB | -0.0794 |
| maltose regulatory prt sfs1=sugar fermentation stimulation protein | g1786340 | sfsA | -1.3187 |
| tdcABC operon transcriptional activator | g1789506 | tdcA | -1.5098 |
| tdcABC operon transcriptional activator | g1789507 | tdcR | -2.273 |
| torCAD operon transcriptional regulatory protein | g1787229 | torR | -0.4632 |
| "sensor protein TorS, histidine protein kinase EC2.7.3.-" | g1787227 | torS | -0.5623 |
| regulatory gene for treBC operon | g1790689 | treR | -0.2309 |
| Trp repressor | g1790854 | trpR | -1.0563 |
| transcriptional regulatory prt | g1787583 | tyrR | -0.7819 |
| transcriptional regulatory protein | g1790102 | uhpA | -0.3205 |
| regulatory protein | g1790100 | uhpC | -1.2827 |
| uxu operon regulator | g1790780 | uxuR | -0.1094 |
| xylose operon regulatory prt | g1789993 | xylR | -1.4074 |
| ile repressor protein | g1790669 | yjfA | -0.867 |
10.Replication | | | | |
10.1 Degradation of DNA | | | | |
| endonuclease I EC3.1.21.1 | g1789314 | endA | -0.0442 |
| potential 5'-3' exonuclease EC3.1.11.- | g1789162 | exo | -1.2821 |
| endonuclease IV EC3.1.21.2 | g1788483 | nfo | -0.1478 |
| "endonuclease VIII, DNA N-glycosylase with an AP lyase activity" | g1786932 | nei | -0.8983 |
| endonuclease III EC4.2.99.18 | g1787920 | nth | -0.3583 |
| endonuclease R EC3.1.21.3 | g1790809 | hsdR | 0.292 |
| excinuclease ABC sub A | g1790493 | uvrA | 0.3411 |
| excinuclease ABC sub B | g1786996 | uvrB | 0.2021 |
| excinuclease ABC sub C | g1788221 | uvrC | -0.3151 |
| exodeoxyribonuclease V EC3.1.11.5 | g1789183 | recB | -0.2991 |
| exodeoxyribonuclease V EC3.1.11.5 | g1789186 | recC | -0.1757 |
| exodeoxyribonuclease V EC3.1.11.5 | g1789182 | recD | -0.7057 |
| single-stranded DNA-specific exonuclease EC3.1.-.- | g1789259 | recJ | -0.3414 |
| exodeoxyribonuclease VIII | g1787612 | recE | -0.466 |
| exodeoxyribonuclease I EC3.1.11.1 | g1788321 | sbcB | -0.6366 |
| exonuclease | g1786597 | sbcC | -0.6295 |
| exonuclease | g1786598 | sbcD | -0.6539 |
| exonuclease III EC3.1.11.2 | g1788046 | xthA | 0.4705 |
"10.2 DNA replication, restriction, modification, recombination, and repair" | | | | |
| DNA-3-methyladenine glycosidase II EC3.2.2.21 | g1788383 | alkA | -1.0915 |
| DNA adenine methylase EC2.1.1.72 | g1789789 | dam | -0.6325 |
| ATP-dependent RNA helicase | g1787605 | dbpA | -1.087 |
| probable ATP-dependent helicase | g1787018 | dinG | -0.4293 |
| DNA-damage-inducible protein d | g1790076 | dinD | -1.5948 |
| dosage-dependent dnaK suppressor prt | g1786338 | dksA | 0.7655 |
| chromosomal replication initiator | g1790137 | dnaA | -0.7343 |
| replicative DNA helicase EC3.6.1.- | g1790486 | dnaB | 0.31 |
| DNA biosynthesis; initiation and chain elongation | g1790823 | dnaC | -0.1675 |
| DNA polymerase III a sub EC2.7.7.7 | g1786381 | dnaE | 0.4812 |
| DNA primasse EC2.7.7.- | g1789447 | dnaG | -0.9552 |
| DNA polymerase III b sub EC2.7.7.7 | g1790136 | dnaN | 0.5303 |
| DNA polymerase III e sub EC2.7.7.7 | g1786409 | dnaQ | -1.4457 |
| DNA biosynthesis; primasomal protein i | g1790824 | dnaT | 0.0697 |
| DNA polymerase III sub g and tau EC2.7.7.7 | g1786676 | dnaX | -0.2409 |
| Hin recombinational enhancer BP | g1789661 | fis | 1.4376 |
| glucose-inhibited division prt | g1790180 | gidA | 0.7331 |
| glucose-inhibited division prt | g1790179 | gidB | -0.3567 |
| "DNA gyrase, sub A EC5.99.1.3" | g1788562 | gyrA | 1.5155 |
| "DNA gyrase, sub B EC5.99.1.3" | g1790134 | gyrB | 1.8763 |
| helicase IV (75 kD helicase) EC3.6.1.- | g1787196 | helD | -0.6429 |
| integration host factor a sub | g1788005 | himA | -0.8965 |
| integration host factor b sub(IHF-b) | g1787141 | himD | -0.7451 |
| DNA polymerase III d sub EC2.7.7.7 | g1786859 | holA | -1.1417 |
| DNA polymerase III d' sub EC2.7.7.7 | g1787341 | holB | -0.6963 |
| DNA polymerase III c sub EC2.7.7.7 | g1790709 | holC | -0.2774 |
| DNA polymerase III psi sub EC2.7.7.7 | g1790831 | holD | -0.6844 |
| ATP-dependent helicase | g1787681 | hrpA | 0.1475 |
| ATP-dependent helicase | g1786342 | hrpB | -0.7904 |
| DNA methylase M; host modification EC2.1.1.72 | g1790808 | hsdM | 0.9378 |
| type I restriction enzyme ecoki specificity | g1790807 | hsdS | -1.7552 |
| restriction alleviation and modification enhancement protein | g1787610 | lar | -2.7971 |
| probable ATP-dependent helicase EC3.6.1.- | g1787942 | lhr | -1.0204 |
| DNA ligase EC6.5.1.2 | g1788750 | lig | 0.2896 |
| 5-methylcytosine-specific restriction enzyme A EC3.1.21.- | g1787406 | mcrA | -2.4152 |
| restriction of DNA at 5-methylcytosine residues EC3.1.21.- | g1790805 | mcrB | -1.6079 |
| sequences restricted | g1790804 | mcrC | -2.0294 |
| modulation of initiation at oriC | g1790181 | mioC | -0.0249 |
| restriction of methylated adenine | g1790811 | mrr | -0.629 |
| mutator mutT EC3.6.1.- | g1786288 | mutT | -0.8311 |
| transcription-repair coupling factor | g1787357 | mfd | -0.0966 |
| formamidopyrimidine-DNA glycosylase EC3.2.2.- | g1790066 | mutM | -0.9538 |
| A/G-specific adenine glycosylase EC3.2.2.- | g1789331 | mutY | -1.1279 |
| DNA mismatch repair prt | g1789196 | mutH | -1.1114 |
| DNA mismatch repair prt | g1790612 | mutL | -0.3926 |
| DNA mismatch repair prt | g1789089 | mutS | 0.2646 |
| O6-methylguanine-DNA-alkyltransferase EC2.1.1.63 | g1787596 | ogt | -1.502 |
| topoisomerase IV sub A EC5.99.1.- | g1789396 | parC | 0.609 |
| topoisomerase IV sub B EC5.99.1.- | g1789408 | parE | 0.4245 |
| deoxyribodipyrimidine photolyase EC4.1.99.3 | g1786926 | phrB | -0.9703 |
| DNA-invertase | g1787404 | pin | -1.4715 |
| DNA polymerase I EC2.7.7.7 | g1790294 | polA | 0.3156 |
| DNA polymerase II EC2.7.7.7 | g1786246 | polB | -0.0675 |
| primosomal prt replication factor | g1790370 | priA | -0.1184 |
| primosomal replication protein n | g1790645 | priB | -1.2145 |
| primosomal replication protein N | g1786673 | priC | -0.4956 |
| DNA recombinase EC3.6.1.- | g1790084 | recG | -0.1319 |
| DNA helicase EC3.6.1.- | g1790256 | recQ | -0.009 |
| "DNA, ATP-BP" | g1790135 | recF | -0.8788 |
| recombinase | g1789051 | recA | 2.3823 |
| recombination and DNA repair | g1788969 | recN | -0.3083 |
| binds ssDNA and promotes renaturation | g1787611 | recT | -0.6035 |
| recombination protein | g1786678 | recR | 0.4379 |
| rep helicase EC3.6.1.- | g1790212 | rep | 0.1025 |
| putative ATP-dependent RNA helicase | g1787016 | rhlE | 0.8293 |
| Holliday junction DNA helicase | g1788168 | ruvA | -0.7249 |
| Holliday junction DNA helicase | g1788167 | ruvB | -0.2393 |
| crossover junction endodeoxyribonuclease | g1788170 | ruvC | -0.032 |
| negative modulator of initiation of replication | g1786903 | seqA | -0.4483 |
| single-stranded DNA BP | g1790494 | ssb | 1.8515 |
| topoisomerase III EC5.99.1.2 | g1788061 | topB | -0.3011 |
| DNA 3-methyladenine glycosidase I EC3.2.2.20 | g1789971 | tag | -0.9653 |
| DNA topoisomerase I EC5.99.1.2 | g1787529 | topA | 0.6066 |
| DNA replication terminus site-binding protein | g1787895 | tus | -0.8181 |
| DNA helicase II EC3.6.1.- | g1790246 | uvrD | 0.2354 |
| integrase-recombinase prt | g1790244 | xerC | 0.0167 |
| integrase-recombinase prt | g1789261 | xerD | -0.7479 |
| exodeoxyribonuclease small subunit EC3.1.11.6 | g1786624 | xseB | 0.5297 |
11 Transcription | | | | |
11.1 Degradation of RNA | | | | |
| ribonuclease I precursor EC3.1.27.6 | g1786828 | rna | -0.6563 |
| exoribonuclease II EC3.1.13.1 | g1787542 | rnb | 0.3099 |
| ribonuclease D EC3.1.26.3 | g1788105 | rnd | -0.0776 |
| ribonuclease E | g1787325 | rne | 0.8602 |
| RNase P EC3.1.26.5 | g1790139 | rnpA | -1.3889 |
| ribonuclease H EC3.1.26.4 | g1786408 | rnhA | -0.8534 |
| ribonuclease HII EC3.1.26.4 | g1786380 | rnhB | 0.0419 |
| RNase T EC3.1.13.- | g1787941 | rnt | 0.377 |
| ribonuclease PH | g1790074 | rph | 0.6852 |
"11.2 RNA synthesis, modification, and DNA transcription" | | | | |
| ATP-dependent helicase | g1786245 | hepA | 1.2176 |
| ATP-dependent RNA helicase | g1790214 | rhlB | 0.2489 |
| DNA-directed RNA polymerase a chain EC2.7.7.6 | g1789690 | rpoA | 0.8427 |
| DNA-directed RNA polymerase b chain EC2.7.7.6 | g1790419 | rpoB | 2.1308 |
| DNA-directed RNA polymerase b' chain EC2.7.7.6 | g1790420 | rpoC | 2.6183 |
| RNA polymerase sigma-70 factor | g1789448 | rpoD | 1.9194 |
| RNA polymerase sigma-32 factor EC2.7.7.6 | g1789871 | rpoH | 1.4561 |
| RNA polymerase sigma-54 factor (sigma-N) | g1789594 | rpoN | -0.0914 |
| RNA polymerase sigma subunit RpoS (sigma-38) | g1789098 | rpoS | -0.0741 |
| RNA polymerase omega sub EC2.7.7.6 | g1790081 | rpoZ | 1.1762 |
| transcription terminator | g1789560 | nusA | 1.4698 |
| N utilization substance prt B | g1786618 | nusB | 0.5914 |
| transcription antitermination prt | g1790414 | nusG | 1.4591 |
| poly(A) polymerase EC2.7.7.19 | g1786336 | pcnB | 0.8346 |
| polynucleotide phosphorylase EC2.7.7.8 | g1789555 | pnp | 2.2702 |
| transcription elongation factor | g1789810 | greB | 0.244 |
13.Translation | | | | |
13.1 Amino acyl tRNA synthetases | | | | |
| Ala-tRNA Sase EC6.1.1.7 | g1789048 | alaS | 1.0183 |
| Arg-tRNA Sase EC6.1.1.19 | g1788184 | argS | 1.2454 |
| Asn-tRNA Sase EC6.1.1.22 | g1787161 | asnS | 1.1332 |
| Asp-tRNA Sase EC6.1.1.12 | g1788173 | aspS | 1.9173 |
| Cys-tRNA Sase EC6.1.1.16 | g1786737 | cysS | 0.9575 |
| Gln-tRNA Sase EC6.1.1.18 | g1786895 | glnS | 1.6498 |
| Gly-tRNA Sase a chain EC6.1.1.14 | g1789983 | glyQ | 1.5856 |
| Gly-tRNA Sase b chain EC6.1.1.14 | g1789982 | glyS | 1.8776 |
| Ile-tRNA Sase EC6.1.1.5 | g1786209 | ileS | 1.5279 |
| Leu-tRNA Sase EC6.1.1.4 | g1786861 | leuS | 1.8061 |
| Lys-tRNA Sase EC6.1.1.6 | g1789256 | lysS | 1.9273 |
| lysyl-tRNA synthetase EC6.1.1.6 | g1790571 | lysU | 0.2939 |
| lysyl-tRNA synthetase analog EC6.1.1.6 | g1790599 | yjeA | -0.5732 |
| Met-tRNA Sase EC6.1.1.10 | g1788432 | metG | 1.3537 |
| Phe-tRNA Sase a sub EC6.1.1.20 | g1788007 | pheS | 1.2934 |
| Phe-tRNA Sase b sub EC6.1.1.20 | g1788006 | pheT | 1.4544 |
| Pro-tRNA Sase EC6.1.1.15 | g1786392 | proS | 1.7959 |
| Ser-tRNA Sase EC6.1.1.11 | g1787120 | serS | 1.2485 |
| Thr-tRNA Sase EC6.1.1.3 | g1788013 | thrS | 0.7781 |
| Trp-tRNA Sases EC6.1.1.2 | g1789786 | trpS | 1.0241 |
| Tyr-tRNA Sase EC6.1.1.1 | g1787925 | tyrS | 1.196 |
| Val-tRNA Sase EC6.1.1.9 | g1790708 | valS | 2.018 |
13.2 tRNA modification | | | | |
| tRNA nucleotidyltransferase EC2.7.7.25 | g1789436 | cca | -0.3512 |
| Met-tRNA formyltransferase EC2.1.2.9 | g1789683 | fmt | -0.3751 |
| tRNA delta-2-isopentenylpyrophosphate (IPP) transferase EC2.5.1.- | g1790613 | miaA | -1.248 |
| peptidyl-tRNA hydrolase EC3.1.1.29 | g1787455 | pth | -1.3006 |
| S-adenosylmethionine:tRNA ribosyltransferase- isomerase | g1786606 | queA | -0.2771 |
? | selenium metabolism prt | g1788062 | selD | 0.2253 |
| tRNA-guanine transglycosylase EC2.4.2.29 | g1786607 | tgt | 0.2778 |
| tRNA (U-5-)-MTase EC2.1.1.35 | g1790403 | trmA | -0.0428 |
| tRNA(guanine-7)methyltransferase EC2.1.1.31 | g1788959 | trmD | -0.8654 |
| pseudouridylate synthase I EC4.2.1.70 | g1788657 | truA | -0.2932 |
| trna pseudouridine 55 synthase (psi55 synthase) | g1789557 | truB | 0.4287 |
"13.3 Degradation of proteins, peptides, and glycopeptides" | | | | |
| ATP-dependent Clp protease ATP-binding subunit | g1787109 | clpA | 0.4754 |
| ATP-dependent clp protease proteolytic subunit EC3.4.21.92 | g1786641 | clpP | 0.0233 |
| ATP-dependent protease ATPase sub | g1786642 | clpX | 1.1301 |
| D-alanine carboxypeptidase EC3.4.16.4 | g1786851 | dacA | 0.7303 |
| dipeptidyl carboxypeptidase II EC3.4.15.5 | g1787819 | dcp | -0.7528 |
| HflC EC3.4.-.- | g1790617 | hflC | 1.691 |
| protease for l cII repressor | g1790616 | hflK | 0.7658 |
| protease EC3.4.21.- | g1789629 | hhoA | -1.0764 |
| protease EC3.4.21.- | g1789630 | hhoB | 0.0635 |
| type 4 prepilin-like protein specific leader peptidase | g1789732 | hofD | -1.5859 |
| periplasmic Ser protease Do EC3.4.21.- | g1786356 | htrA | 1.545 |
| isoaspartyl dipeptidase EC3.4.19.5 | g1790784 | iadA | -0.0108 |
| penicillin-insensitive murein endopeptidase EC3.4.99.- | g1788668 | mepA | -0.5311 |
| lon protease EC3.4.21.53 | g1786643 | lon | 1.2109 |
| protease VII precursor EC3.4.21.87 | g1786777 | ompT | -1.317 |
| aminopeptidase A EC3.4.11.1 | g1790710 | pepA | 0.6297 |
| peptidase D EC3.4.13.3 | g1786432 | pepD | 1.4654 |
| peptidase E | g1790452 | pepE | 0.3499 |
| aminopeptidase N EC3.4.11.2 | g1787163 | pepN | 0.6279 |
| aminopeptidase P EC3.4.11.9 | g1789275 | pepP | 0.3772 |
| Pro dipeptidase EC3.4.13.9 | g1790282 | pepQ | 1.1521 |
| peptidase T EC3.4.11.- | g1787372 | pepT | -0.2552 |
| tail-specific protease EC3.4.21.- | g1788134 | prc | 0.0848 |
| oligopeptidase A | g1789913 | prlC | 1.1393 |
| protease III precursor (pitrilysin) EC3.4.24.55 | g1789184 | ptr | -0.5855 |
| protease II EC3.4.21.83 | g1788150 | ptrB | -0.7961 |
| ATP-dependent protease | g1790850 | sms | -0.0335 |
| protease EC3.4.-.- | g1787527 | sohB | -0.8128 |
| protease IV EC3.4.-.- | g1788064 | sppA | 0.2349 |
13.4 Nucleoproteins | | | | |
| histone-like protein | g1786375 | hlpA | 1.1172 |
| DNA-BP H-NS | g1787489 | hns | 1.0797 |
| histonelike DNA-binding protein HU-alpha (NS2) | g1790433 | hupA | 2.1613 |
| DNA-binding protein HU-beta | g1786644 | hupB | 1.5097 |
| DNA-binding protein | g1789023 | stpA | 0.3357 |
| protamine-like protein | g1787482 | tpr | -1.6564 |
13.5 Protein modification and translation factors | | | | |
| leucyl/phenylalanyl-tRNA--protein transferase EC2.3.2.- | g1787111 | aat | -1.444 |
| f-Met deformylase EC3.5.1.27/EC3.5.1.31 | g1789682 | def | -0.5879 |
| elongation factor P | g1790590 | efp | 2.046 |
| ribosome releasing factor | g1786368 | frr | 1.8025 |
| elongation factor G | g1789738 | fusA | 2.673 |
| Glu-ammonia-ligase adenylyltransferase EC2.7.7.42 | g1789433 | glnE | -0.3625 |
| initiation factor IF-1 | g1787110 | infA | 0.1376 |
| initiation factor IF-2 | g1789559 | infB | 1.9864 |
| initiation factor IF-3 | g1788012 | infC | -0.5397 |
| Met aminopeptidase EC3.4.11.18 | g1786364 | map | 0.7528 |
| peptide methionine sulfoxide reductase | g1790665 | msrA | -0.0311 |
| maturation of antibiotic MccB17 | g1790682 | pmbA | 0.1629 |
| peptidyl-prolyl cis-trans isomerase A EC5.2.1.8 | g1789763 | ppiA | 0.6831 |
| peptidyl-prolyl cis-trans isomerase B EC5.2.1.8 | g1786736 | ppiB | 2.389 |
| peptidyl-prolyl cis-trans isomerase C EC5.2.1.8 | g1790211 | ppiC | 0.5795 |
| peptide chain release factor 1 | g1787462 | prfA | 0.2916 |
| peptide chain release factor 2 | g1789257 | prfB | -1.6634 |
| peptide chain release factor 3 | g1790835 | prfC | 1.4242 |
| peptide chain release factor homolog (RF-H) | g1786431 | prfH | -0.3851 |
| ribosome-binding factor a (p15b protein) | g1789558 | rbfA | 1.2615 |
| "rotamase, peptidyl prolyl cis-trans isomerase" | g1789748 | slyD | 2.1601 |
| elongation factor EF-Ts | g1786366 | tsf | 2.5619 |
| elongation factor EF-Tu | g1789737 | tufA | 3.4349 |
| elongation factor EF-Tu | g1790412 | tufB | 3.2913 |
13.6 Ribosomal proteins | | | | |
| ribosomal prt L1 | g1790416 | rplA | 2.5381 |
| ribosomal prt L2 | g1789713 | rplB | 2.2271 |
| ribosomal prt L3 | g1789716 | rplC | 1.8822 |
| ribosomal prt L4 | g1789715 | rplD | 2.6539 |
| ribosomal prt L5 | g1789704 | rplE | 1.5816 |
| ribosomal prt L6 | g1789701 | rplF | 2.0139 |
| ribosomal prt L7/L12 | g1790418 | rplL | 2.95 |
| ribosomal prt L9 | g1790647 | rplI | 1.9844 |
| ribosomal prt L10 | g1790417 | rplJ | 2.0104 |
| ribosomal prt L11 | g1790415 | rplK | 2.5318 |
| ribosomal prt L13 | g1789626 | rplM | 1.4328 |
| ribosomal prt L14 | g1789706 | rplN | 1.196 |
| ribosomal prt L15 | g1789697 | rplO | 2.6348 |
| ribosomal prt L16 | g1789709 | rplP | 1.8794 |
| ribosomal prt L17 | g1789689 | rplQ | 1.1971 |
| ribosomal prt L18 | g1789700 | rplR | 2.0975 |
| ribosomal prt L19 | g1788958 | rplS | 2.1649 |
| ribosomal prt L20 | g1788009 | rplT | 2.2355 |
| ribosomal prt L21 | g1789577 | rplU | 1.3619 |
| ribosomal prt L22 | g1789711 | rplV | 1.6465 |
| ribosomal prt L23 | g1789714 | rplW | 3.0056 |
| ribosomal prt L24 | g1789705 | rplX | 1.8774 |
| ribosomal prt L25 | g1788512 | rplY | 2.5754 |
| ribosomal prt L27 | g1789576 | rpmA | 2.442 |
| ribosomal prt L28 | g1790068 | rpmB | 2.7271 |
| ribosomal prt L29 | g1789708 | rpmC | 1.2 |
| ribosomal prt L30 | g1789698 | rpmD | 0.9662 |
| ribosomal prt L31 | g1790371 | rpmE | 1.9303 |
| ribosomal prt L32 | g1787330 | rpmF | 1.8388 |
| ribosomal prt L33 | g1790067 | rpmG | 2.5569 |
| ribosomal prt L34 | g1790138 | rpmH | 2.5514 |
| ribosomal prt L35 | g1788010 | rpmI | 2.5834 |
| ribosomal prt L36 | g1789695 | rpmJ | -0.4878 |
| ribosomal prt S1 | g1787140 | rpsA | 2.8912 |
| ribosomal prt S2 | g1786365 | rpsB | 2.7448 |
| ribosomal prt S3 | g1789710 | rpsC | 2.5502 |
| ribosomal prt S4 | g1789691 | rpsD | 1.5334 |
| ribosomal prt S5 | g1789699 | rpsE | 1.7558 |
| ribosomal prt S6 | g1790644 | rpsF | 2.3295 |
| ribosomal prt S7 | g1789739 | rpsG | 1.1594 |
| ribosomal prt S8 | g1789702 | rpsH | 1.5176 |
| ribosomal prt S9 | g1789625 | rpsI | 3.1495 |
| ribosomal prt S10 | g1789717 | rpsJ | 2.0304 |
| ribosomal prt S11 | g1789692 | rpsK | 1.5251 |
| ribosomal prt S12 | g1789740 | rpsL | 2.3884 |
| ribosomal prt S13 | g1789693 | rpsM | 0.5929 |
| ribosomal prt S14 | g1789703 | rpsN | 1.2627 |
| ribosomal prt S15 | g1789556 | rpsO | 1.7888 |
| ribosomal prt S16 | g1788961 | rpsP | 1.3507 |
| ribosomal prt S17 | g1789707 | rpsQ | 2.5478 |
| ribosomal prt S18 | g1790646 | rpsR | 1.9423 |
| ribosomal prt S19 | g1789712 | rpsS | 0.7546 |
| ribosomal prt S20 | g1786206 | rpsT | 2.0557 |
| ribosomal prt S21 | g1789446 | rpsU | 2.7574 |
| ribosomal prt S22 | g1787755 | rpsV | -0.1085 |
13.7 synthesis and modification | | | | |
| methylation of 50S ribosomal subunit protein L11 | g1789657 | prmA | 0.3793 |
| ribosomal prt S6 modification prt | g1787076 | rimK | -0.1416 |
| ribosomal-protein-serine acetyltransferase EC2.3.1.- | g1787697 | rimL | -1.0747 |
| ribosomal-prt-Ala acetyltransferase EC2.3.1.128 | g1790832 | rimI | -0.8214 |
| acetylates N-terminal alanine of ribosomal proteinS5 EC2.3.1.128 | g1787305 | rimJ | -1.1116 |
| ribosome modulation factor (protein E) | g1787186 | rmf | -1.3859 |
14.Transport and binding protein | | | | |
"14.1 Amino acids, peptides and amines" | | | | |
| lysine-arginine-ornithine-binding periplasmic protein | g1788649 | argT | 0.2733 |
| aromatic amino acid transport protein | g1786302 | aroP | 0.8347 |
| Arg-BP | g1787088 | artI | 1.7464 |
| arginine-binding periplasmic protein 2 | g1787085 | artJ | 0.711 |
| Arg permease | g1787086 | artM | 0.0597 |
| Arg transport ATP-BP | g1787089 | artP | 0.7699 |
| Arg permease | g1787087 | artQ | -0.2717 |
| LIV-II transport system=branched chain amino acid transport system II | g1786601 | brnQ | 1.0454 |
| d-serine/d-alanine/glycine transporter | g1790653 | cycA | -0.4309 |
| ammonium transport protein | g1790659 | cysQ | 0.6036 |
| dipeptide transporter | g1789966 | dppA | 1.3962 |
| dipeptide permease | g1789965 | dppB | 0.2043 |
| dipeptide permease | g1789964 | dppC | 0.6704 |
| dipeptide transport ATP-BP | g1789963 | dppD | 0.3053 |
| dipeptide transport ATP-BP | g1789962 | dppF | 0.5365 |
| DsdX permease | g1788707 | dsdX | -1.3738 |
| biopolymer transport prt | g1789381 | exbB | 0.2274 |
| biopolymer transport prt | g1789380 | exbD | -0.3935 |
| GabA permease (4-amino butyrate transport carrier) | g1789017 | gabP | -0.9215 |
| Gln-BP | g178703? | glnH | 1.6322 |
| Gln permease | g1787030 | glnP | 0.9419 |
| glutamine transport ATP-binding protein | g1787029 | glnQ | 1.1193 |
| glutamate/aspartate transport system permease | g1786874 | gltJ | -0.0934 |
| glutamate/aspartate transport system permease | g1786873 | gltK | 0.0725 |
| glutamate/aspartate transport ATP-binding | g1786872 | gltL | 0.9729 |
| Glu permease | g1790085 | gltS | 0.1989 |
| proton Glu symport prt | g1790514 | gltP | 1.007 |
| histidine-binding periplasmic protein | g1788648 | hisJ | 0.1155 |
| histidine transport ATP-binding protein | g1788644 | hisP | -0.431 |
| histidine transport system permease protein | g1788646 | hisQ | -0.1761 |
| high-affinity branched-chain amino acid transport ATP-binding | g1789863 | livF | -0.0267 |
| Leu-specific transport prt | g1789864 | livG | 0.1217 |
| high-affinity branched chain amino acid transport system | g1789866 | livH | 0.7403 |
| leu/ile/val-binding protein precursor | g1789870 | livJ | 1.0674 |
| "leucine-specific binding protein precursor""" | g1789867 | livK | 0.889 |
| high-affinity branched chain amino acid transport system | g1789865 | livM | 0.5817 |
| lysine-specific permease | g1788480 | lysP | 1.4136 |
| oligopeptide-BP | g1787495 | oppA | 0.1907 |
| oligopeptide permease | g1787497 | oppB | -0.6915 |
| oligopeptide permease | g1787498 | oppC | -0.0361 |
| oligopeptide permease ATP-BP | g1787499 | oppD | -0.4458 |
| oligopeptide permease ATP-BP | g1787500 | oppF | -0.2491 |
| phenylalanine-specific permease | g1786789 | pheP | 0.3026 |
| high-affinity transport system for glycine betaine and proline | g1789032 | proV | -1.2335 |
| high-affinity transport system for glycine betaine and proline | g1789033 | proW | -0.2177 |
| glycine betaine-binding periplasmic protein | g1789034 | proX | 0.4922 |
| peptide permease | g1787551 | sapA | -0.5413 |
| peptide permease | g1787550 | sapB | -0.669 |
| peptide permease | g1787549 | sapC | -0.1554 |
| peptide permease ATP-BP | g1787548 | sapD | -0.5633 |
| uptake of the peptide antibiotic microcin B17 | g1786575 | sbmA | 0.2918 |
| Ser transporter | g1789160 | sdaC | 2.2982 |
| low affinity tryptophan permease | g1790145 | tnaB | -0.5248 |
| spermidine-putrescine permease ATP-BP | g1787370 | potA | -0.0744 |
| spermidine-putrescine permease | g1787369 | potB | 0.7129 |
| spermidine-putrescine permease | g1787368 | potC | -0.0869 |
| spermidine-putrescine-BP | g1787367 | potD | 1.0375 |
| putrescine permease=putrescine-ornithine antiporter | g1786908 | potE | 0.3169 |
| putrescine-binding periplasmic protein | g1787078 | potF | 0.1471 |
| putrescine transport system permease protein | g1787080 | potH | -0.3121 |
| putrescine transport system permease protein | g1787081 | potI | -1.2456 |
| active uptake of proline or betaine | g1790550 | proP | 0.1796 |
| threonine-serine permease | g1789504 | tdcC | 1.1473 |
| Tyr-specific transport prt | g1788218 | tyrP | -0.7804 |
| trp repressor binding protein | g1787239 | wrbA | 0.1625 |
14.2 Anions | | | | |
| putative sulfate transport protein | g1788753 | cysZ | -0.7844 |
| cyanate permease EC4.2.1.1 | g1786534 | cynT | -0.5317 |
| low-affinity phosphate transport | g1789907 | pitA | 0.5208 |
| peripheral membrane prt B | g1790162 | pstB | 1.6946 |
| peripheral membrane prt C | g1790164 | pstC | 1.055 |
| periplasmic phosphate-BP | g1790165 | pstS | 0.7466 |
| phosphate transport system permease protein | g1790163 | pstA | 1.2445 |
| periplasmic sulphate binding protein | g1790351 | sbp | 0.2442 |
"14.3 Carbohydrates, organic alcohols, and acids" | | | | |
(PTS) | | | | |
| "PTS system, n-acetylgalactosamine-specific IIb" | g1789527 | agaB | 0.0318 |
| "pts system, n-acetylgalactosamine-specific IIC" | g1789528 | agaC | -0.8765 |
| "pts system, n-acetylgalactosamine-specific IID" | g1789529 | agaD | 0.1493 |
| "pts system, n-acetylgalactosamine-specific IIb component2" | g1789521 | agaV | -0.1323 |
| "pts system, n-acetylgalactosamine-specific IIc component2" | g1789522 | agaW | 0.0432 |
| phosphotransferase enzyme IIABC-Asc | g1789069 | ascF | -0.0969 |
| "pts system, cellobiose-specific IIB component EC2.7.1.69" | g1788034 | celA | -0.4248 |
| phosphoenolpyruvate dependent phosphotransferaseenzymeII-cellobiose | g1788032 | celB | -0.2059 |
| phosphoenolpyruvate dependent phosphotransferase enzymeIII-cellobiose EC2.7.1.69 | g1788031 | celC | -1.3385 |
| "Glc phosphotransferase enzyme III=?pts system, glucose-specific IIA component" | g1788757 | crr | 1.7899 |
| "pts system, fructose-like-1 IIbc component (phosphotransferas)" | g1790333 | frvB | 0.2039 |
| "pts system, fructose-like-2 IIc component (phosphotransferase)" | g1790386 | frwC | 0.6757 |
| "pts system, fructose-like-2 IIb component 1 (phosphotransfera)" | g1790387 | frwB | 0.324 |
| "pts system, fructose-like-2 IIb component 2 (phosphotransfera)" | g1790390 | frwD | -0.4753 |
| "pts system, galactitol-specific IIA component" | g1788410 | gatA | -1.6974 |
| "pts system, galactitol-specific IIB component" | g1788409 | gatB | -1.5558 |
| "pts system, arbutin-like IIb component " | g1790116 | glvB | 0.5038 |
| pts system arbutin-like IIC component | g1790117 | glvC | -0.2751 |
| "pts system, maltose and glucose-specific II ABC component " | g1787908 | malX | 0.0854 |
| "phosphotransferase enzyme II, AB component EC2.7.1.69" | g1788120 | manX | 0.374 |
| "phosphotransferase enzyme II, C component" | g1788121 | manY | 1.7215 |
| "phosphotransferase enzyme II, D component" | g1788122 | manZ | 1.6177 |
| mannitol-specific enzyme II of phosphotransferasesystem | g1790027 | mtlA | 1.7582 |
| phosphocarrier protein Npr (nitrogen related hpr) | g1789599 | ptsO | -0.6167 |
| "PTS system, glucose-specific IIBC component EC2.7.1.69" | g1787343 | ptsG | 1.8355 |
| phosphocarrier protein Hpr | g1788755 | ptsH | 0.9404 |
| phosphoenolpyruvate-protein phosphotransferase EC2.7.3.9 | g1788756 | ptsI | 0.9655 |
| PTS related carbon and organic nitrogen regulation EC2.7.1.69 | g1789597 | ptsN | -0.273 |
| PTS related carbon and organic nitrogen regulation EC2.7.3.9 | g1789193 | ptsP | -0.7328 |
| "PTS system, glucitol/sorbitol-specific IIA EC2.7.1.69" | g1789056 | srlB | -0.5968 |
| phosphotransferase system trehalose permease | g1790688 | treB | -0.3864 |
(Others) | | | | |
| low affinity L-arabinose transport system EC5.3.1.4 | g1789207 | araE | 0.0168 |
| L-arabinose-binding periplasmic protein | g1788211 | araF | 0.9503 |
| L-arabinose transport ATP-binding protein AraG | g1788210 | araG | -0.4912 |
| l-arabinose transport system permease protein | g1788208 | araH | -0.1017 |
| transport protein | g1790159 | bglF | -0.8958 |
| cryptic mannitol transport EC2.7.1.69 | g1789301 | cmtA | -0.2516 |
| cryptic mannitol transport EC2.7.1.69 | g1789302 | cmtB | -2.3245 |
| uptake of C4-dicarboxylic acids | g1789947 | dctA | 0.8107 |
| Asp transport prt | g1790580 | dcuA | 1.4913 |
| anaerobic c4-dicarboxylate transporter dcub | g1790565 | dcuB | 0.9416 |
| probable formate transporter (formate channel) | g1787132 | focA | -0.0886 |
| fructose permease IIBC component EC2.7.1.69 | g1788492 | fruA | 1.0318 |
| fructose permease IIA/FPR component EC2.7.1.69 | g1788494 | fruB | 0.2513 |
| L-fucose permease | g1789166 | fucP | -0.8876 |
| fucose operon prt | g1789169 | fucU | -1.3791 |
| galactose-proton symport (galactose transporter | g1789312 | galP | 0.6022 |
| gluconate permease | g1790776 | gntP | 0.8255 |
| glycerol-3-phosphatase transporter | g1788573 | glpT | 0.1798 |
| high-affinity gluconate transporter | g1789820 | gntT | 1.5447 |
| alpha-ketoglutarate permease | g1788942 | kgtP | -1.2538 |
| potassium channel homolog | g1787503 | kch | -1.7194 |
| 2-keto-3-deoxygluconate transport | g1790343 | kdgT | -0.3743 |
| lactose permease (lactose-proton symport) | g1786538 | lacY | -0.2622 |
| lactam utilization prt=phage lambda receptor protein | g1790469 | lamB | 0.8699 |
| l-lactate permease | g1790031 | lldP | 0.4906 |
| periplasmic maltose-binding protein | g1790466 | malE | 1.5855 |
| maltose transport inner membrane protein | g1790465 | malF | -0.0375 |
| maltose transport inner membrane protein | g1790464 | malG | 0.8419 |
| cytoplasmic membrane protein for maltose uptake | g1790467 | malK | 0.4849 |
| thiomethylgalactoside permease II | g1790561 | melB | -1.1967 |
| methylgalactoside permease ATP-BP | g1788472 | mglA | -0.8111 |
| methylgalactoside-BP | g1788473 | mglB | 1.4467 |
| methylgalactoside permease | g1788471 | mglC | 0.3784 |
| high affinity ribose transport prt | g1790190 | rbsA | -0.1232 |
| periplasmic ribose-BP | g1790192 | rbsB | 0.7415 |
| high affinity ribose transport prt | g1790191 | rbsC | 0.1908 |
| high affinity ribose transport prt | g1790189 | rbsD | -0.4857 |
| rhamnose permease | g1790341 | rhaT | -0.5927 |
| sn-Glycerol-3-phosphate transport system permease protein | g1789861 | ugpA | 0.3125 |
| glycerol-3-phosphate-binding periplasmic protein precursor | g1789862 | ugpB | 0.6594 |
| sn-Glycerol-3-phosphate transport ATP-binding | g1789859 | ugpC | -0.1713 |
| sn-Glycerol-3-phosphate transport system permease protein | g1789860 | ugpE | 0.1196 |
| hexose phosphate transport protein | g1790099 | uhpT | -1.0659 |
| hexose phosphate transport protein; sensor protein EC2.7.3.- | g1790101 | uhpB | -0.4487 |
| glucuronide permease | g1787902 | uidB | -0.3553 |
| xylose-proton symport | g1790463 | xylE | 0.2749 |
| D-xylose transport ATP-BP | g1789991 | xylG | -1.1677 |
| ribose permease | g1789992 | xylH | -0.4663 |
14.4. Cations | | | | |
| cation transport protein | g1787470 | chaC | -0.6272 |
| magnesium and cobalt transport prt | g1790248 | corA | 0.8549 |
| iron(III) dicitrate transport protein | g1790743 | fecA | 0.4807 |
| citrate-dependent iron transport; periplasmic protein | g1790742 | fecB | 0.0896 |
| iron(III) dicitrate transport system permease | g1790741 | fecC | -0.1918 |
| iron(III) dicitrate permease | g1790740 | fecD | -0.3318 |
| iron(III) dicitrate transport ATP-BP | g1790739 | fecE | -1.2607 |
| nickel-binding periplasmic protein | g1789887 | nikA | 0.3132 |
| ferrous iron transport protein a | g1789812 | feoA | -0.652 |
| ferrous iron transport protein b | g1789813 | feoB | 0.9641 |
| ferric enterobactin transport ATP-BP | g1786803 | fepC | -0.8465 |
| ferrichrome-iron receptor | g1786344 | fhuA | 1.0082 |
| Fe(III)-ferrioxamine Band Fe(III)-rhodotrulic acid | g1787344 | fhuE | -0.4726 |
| potassium-transporting ATPase A chain EC3.6.1.36 | g1786915 | kdpA | -0.3039 |
| potassium-transporting ATPase B chain EC3.6.1.36 | g1786914 | kdpB | 0.365 |
| potassium-transporting ATPase C chain EC3.6.1.36 | g1786913 | kdpC | -0.7125 |
| glutathione-regulated potassium-efflux system | g1789749 | kefB | -0.576 |
| (glutathione-regulated) potassium efflux system | g1786232 | kefC | -0.1827 |
| "Mg(2+) transport ATPase, P-type 1 EC3.6.1.-" | g1790690 | mgtA | -0.3301 |
| molybdate-binding periplasmic protein | g1786979 | modA | 0.7287 |
| molybdenum transport system permease protein | g1786980 | modB | -0.1225 |
| molybdenum transport ATP-binding protein | g1786981 | modC | -0.3096 |
| putative molybdenum transport ATP-binding protein; photorepair protein PhrA | g1786975 | modF | -0.908 |
| "Na+, H+ antiporter " | g1787435 | nhaB | 0.2004 |
| "Na+, H+ antiporter 1" | g1786201 | nhaA | -0.4718 |
| nickel transport system permease protein | g1789888 | nikB | 0.4956 |
| "sodium, Pro symporter" | g1787251 | putP | 0.3033 |
| energy transducer | g1787505 | tonB | -1.5366 |
| TRK system potassium uptake prt | g1789685 | trkA | -0.5746 |
| trk system potassium uptake protein | g1787626 | trkG | -2.3163 |
"14.5 Nucleosides, purines and pyrimidines" | | | | |
| nucleoside permease | g1788737 | nupC | 1.423 |
| transport of nucleosides | g1789336 | nupG | 0.9154 |
| cytosine permease | g1786530 | codB | -0.5635 |
| xanthosine permease | g1788745 | xapB | -0.5273 |
14.6 Other | | | | |
| ATP-BP | g1786398 | abc | 0.4756 |
| aerotaxis receptor protein | g1789453 | air | -0.2819 |
| high-affinity choline transport prt | g1786506 | betT | 0.0403 |
| "receptor for vitamin B12, E colicins, and phage BF23" | g1790405 | btuB | -0.5739 |
| vitamin B12 transport system permease protein | g1788004 | btuC | -1.0457 |
| vitamin B12 transport | g1788002 | btuD | -0.7774 |
| vitamin B12 transport periplasmic protein | g1788003 | btuE | -0.2525 |
| probable carnitine transporter | g1786224 | caiT | 0.3487 |
| heme exporter protein A | g1788529 | ccmA | -1.3407 |
| heme exporter protein B | g1788528 | ccmB | -0.4621 |
| heme exporter protein C | g1788527 | ccmC | 0.1306 |
| heme exporter protein D | g1788526 | ccmD | 0.4122 |
| sulfate transport ATP-binding protein CysA | g1788761 | cysA | 0.5254 |
| sulfate transport system permease protein | g1788762 | cysW | 0.023 |
| sulfate transport system permease protein CysT | g1788764 | cysU | -0.0522 |
| thiosulfate-binding protein precursor | g1788765 | cysP | 1.2428 |
| hexuronate transporter | g1789479 | exuT | 1.4188 |
| long-chain fatty acid transport protein | g1788686 | fadL | 0.3513 |
| ferric enterobactin transport protein | g1786802 | fepE | -1.1488 |
| ferric enterobactin transport protein | g1786804 | fepG | -0.2715 |
| ferric enterobactin transport protein | g1786805 | fepD | -0.4819 |
| ferrienterobactin-binding periplasmic protein | g1786807 | fepB | -0.6401 |
| ferrichrome transport protein | g1786347 | fhuB | -0.2572 |
| ferrichrome transport ATP-binding protein | g1786345 | fhuC | -0.2094 |
| ferrichrome-binding periplasmic protein | g1786346 | fhuD | -0.8038 |
| electron transport from formate to hydrogen | g1789067 | hydN | 1.0052 |
| outer membrane lipoprotein carrier protein | g1787118 | lolA | 0.3516 |
| ATP-depepndent translocator | g1787143 | msbA | 0.4178 |
| pantothenate permease | g1789656 | panF | -0.5999 |
| phosphonates transport ATP-binding protein | g1790544 | phnC | 0.3838 |
| phosphonates transport ATP-binding protein | g1790532 | phnN | -0.5725 |
| phosphonates transport ATP-binding protein | g1790534 | phnL | 0.6104 |
| phosphonates transport ATP-binding protein | g1790535 | phnK | 0.1296 |
| probable low-affinity inorganic phosphate transporter2 | g1789360 | pitB | -0.3398 |
| NMN transport across the cytoplasmic membrane | g1786965 | pnuC | -0.7998 |
| thiamine-binding periplasmic protein precursor | g1786255 | tbpA | 0.0382 |
| probable transport protein YifK (o461) | g1790230 | yifK | 0.2356 |
15 Other categories | | | | |
15.1 Adaptations and atypical conditions | | | | |
| cold shock-like protein | g1787839 | cspB | -2.8134 |
| cold shock-like protein; multicopy suppresses mukB | g1788126 | cspC | 1.5731 |
| cold shock-like protein | g1787107 | cspD | -1.9571 |
| cold shock-like protein | g1786841 | cspE | 0.4536 |
| cold shock-like protein | g1787840 | cspF | -1.2443 |
| heat shock protein | g1788875 | hscA | 0.5994 |
| heat shock prt | g1788133 | htpX | 1.1251 |
| "membrane protein affecting cell division, growth and high temperature survival" | g1787292 | htrB | -0.4112 |
| heat shock inducible | g1790122 | hslT | 0.7562 |
| heat shock inducible | g1790120 | hslS | 0.4181 |
| survival prt | g1786238 | surA | 1.1662 |
| universal stress prt | g1789909 | uspA | 0.9431 |
| eat shock protein | g1786194 | htgA | -1.5888 |
| heat shock protein C | g1790422 | htrC | -1.7032 |
| extreme acid resistance | g1787768 | xasA | -0.2938 |
15.2 Colicin-related functions | | | | |
| colicin I receptor | g1788478 | cirA | 0.6615 |
| colicin tolerance prt | g1786961 | tolB | 0.8394 |
| colicin V production prt | g1788652 | cvpA | -0.7863 |
| specific tolerance to colicin E1; expression of outer membrane proteins | g1789413 | tolC | 0.2219 |
| "inner membrane prt= TonB-independent uptake of colicinsA,E1,E2,E3,and K" | g1786959 | tolR | -0.0516 |
| "inner membrane prt= TonB-independent uptake of colicinsA,E1,E2,E3,and K" | g1786958 | tolQ | 0.0148 |
| outer membrane integrity prt | g1786960 | tolA | -1.1278 |
15.3 Drug and analog sensitivity | | | | |
| acriflavin resistance protein A | g1786668 | acrA | 0.6373 |
| acriflavine resistance prt | g1786667 | acrB | 1.0378 |
| acriflavine resistance protein | g1789665 | acrE | -0.4506 |
| "resistance to acriflavin, hydrophobic antibiotics,basicdyesanddetergents" | g1789666 | acrF | -0.5265 |
| beta-lactamase precursor EC3.5.2.6 | g1790593 | ampC | -1.4174 |
| beta-lactamase precursor | g1787644 | hslJ | -0.4868 |
| ampD signalling prt | g1786300 | ampD | -0.766 |
| bacitracin resistance protein (putative undecaprenolkinase) | g1789437 | bacA | 0.3638 |
| fosmidomycin resistance protein | g1786686 | fsr | -0.7061 |
| modulator of drug activity A | g1787075 | mdaA | -0.6486 |
| modulator of drug activity B | g1789406 | mdaB | 0.3596 |
| "organic solvent tolerance protein precursor""" | g1786239 | imp | 0.507 |
| multiple antibiotic resistance protein | g1787811 | marA | -0.3463 |
| multiple antibiotic resistance protein | g1787810 | marR | 0.0401 |
| 5-methyltryptophan resistance; tryptophan-specific permease | g1789552 | mtr | 0.1295 |
| polymyxin B resistance protein | g1788593 | pmrD | -2.123 |
| multidrug resistance prt | g1789042 | emrB | -0.1862 |
| multidrug resistance prt | g1789041 | ermA | 0.7963 |
| multidrug resistance protein d | g1790107 | emrD | -0.8667 |
| multidrug resistance protein | g1788710 | emrY | -1.8172 |
| multidrug resistance protein | g1788711 | emrK | -1.8443 |
| "rRNA(adenosine-N6,N6)-dimethyltransferase EC2.1.1.-" | g1786236 | ksgA | 0.1307 |
| tellurite resistance prt | g1787699 | tehA | -0.9432 |
| tellurite resistance prt | g1787700 | tehB | -0.086 |
15.4 Phage-related functions and prophages | | | | |
| host factor-I (HF-I) | g1790614 | hfq | 0.5297 |
| SlpA integrase; prophage cp4-57 integrase | g1788974 | intA | -1.2937 |
| prophage P4 integrase | g1790722 | intB | -1.8614 |
| prophage DLP12 integrase | g1786748 | intD | -1.6832 |
| bacteriophage T4 late gene expression blocking protein | g1787385 | lit | -2.4376 |
| bacteriophage N4 adsorption protein B | g1786781 | nfrB | -0.3976 |
| positive regulator of phage P2 late gene transcription | g1788398 | ogrK | -1.7705 |
| prophage QIN DNA packaging protein NU1 homolog | g1787830 | nohA | -0.4518 |
| phage shock protein A | g1787562 | pspA | 0.129 |
| phage shock protein B | g1787563 | pspB | -0.0937 |
| phage shock protein C | g1787564 | pspC | 0.1637 |
| phage shock protein D | g1787565 | pspD | -0.76 |
| phage shock protein E | g1787567 | pspE | -0.0759 |
| host gene required for lysis of phiX174 infection | g1789747 | slyX | -0.4537 |
| putative prophage sf6-like integrase | g1788690 | yfdB | -1.0975 |
| bacteriophage N4 adsorption protein A | g1786780 | nfrA | -0.5136 |
15.5 Radiation sensitivity | | | | |
| DNA repair prt | g1790069 | radC | -1.3924 |
15.6 Transposon-related functions | | | | |
| insertion element IS1 protein insA | g1786204 | insA_1 | -0.9985 |
| insertion element IS1 protein InsA | g1786460 | insA_2 | -1.0176 |
| insertion element IS1 protein InsA | g1786471 | insA_3 | -1.0176 |
| insertion element IS1 protein InsA | g1788204 | insA_4 | -0.9985 |
| insertion element is1 protein insA | g1789852 | insA_5 | -0.9985 |
| insertion element is1f protein insa | g1790747 | insA_6 | -1.3076 |
| insertion element IS1 protein InsB | g1786457 | insB_1 | -0.2881 |
| insertion element IS1 protein InsB | g1786470 | insB_2 | -0.2881 |
| insertion element IS1 protein InsB | g1787223 | insB_3 | -0.2465 |
| insertion element IS1 protein InsB | g1788203 | insB_4 | -0.3518 |
| insertion element IS1 protein InsB | g1789853 | insB_5 | -0.3518 |
| putative transposase for insertion sequence IS3 | g1786570 | tra5_1 | -0.5628 |
| putative transposase for insertion sequence IS3 | g1786753 | tra5_2 | -0.5628 |
| putative transposase for insertion sequence IS3 | g1787263 | tra5_3 | -0.5628 |
| putative transposase for insertion sequence is3 | g1788405 | tra5_4 | -0.5628 |
| transposase for insertion sequence element IS30 | g1786450 | tra8_1 | -1.3452 |
| transposase for insertion sequence element IS30 | g1787671 | tra8_2 | -1.396 |
| IS30 transposase | g1790736 | tra8_3 | -1.396 |
16 Other | | | | |
| glp regulon prt | g1790360 | glpX | 0.5385 |
| heat shock prt | g1790366 | hslU | 1.8133 |
| heat shock prt EC3.4.99.- | g1790367 | hslV | 0.127 |
| isochorismate Sase EC5.4.99.6 | g1786809 | entC | -0.2751 |
| isochorismate synthase | g1788600 | menF | -0.7165 |
| transport ATP-BP | g1787112 | cydC | -0.8061 |
| transport ATP-BP | g1787113 | cydD | -0.9188 |