Escherichia coli



Function Number Gene Relative PPL
1.Amino acid biosynthesis
1.1 Aromatic amino acid family
e3-phosphoshikimate 1-carboxyvinyltransferase EC2.5.1.19 g1787137 aroA 0.0352
3-dehydroquinate Sase EC4.6.1.3 g1789791 aroB -0.7591
chorismate Sase EC4.6.1.4 g1788669 aroC 0.1334
3-dehydroquinate dehydratase EC4.2.1.10 g1787984 aroD 0.1215
shikimate 5-DHase EC1.1.1.25 g1789675 aroE -1.3242
phospho-2-dehydro-3-deoxyheptonate aldolase EC4.1.2.15 g1788953 aroF -0.0314
DAHP Sase EC4.1.2.15 g1786969 aroG 0.092
3-deoxy-D-arabinoheptulosonate 7-phosphate synthase EC4.1.2.15 g1787996 aroH -0.6203
shikimic acid kinase EC2.7.1.71 g1789792 aroK -0.4301
shikimate kinase II EC2.7.1.71 g1786587 aroL -1.3794
chorismate mutase-prephenate dehydratase 1145 pheA -0.5517
Trp Sase a chain EC4.2.1.20 g1787514 trpA -0.4133
Trp Sase b chain EC4.2.1.20 g1787515 trpB 0.3241
anthranilate isomerase EC4.1.1.48 g1787516 trpC -0.6138
anthranilate Sase component II EC4.1.3.27/EC2.4.2.18 g1787517 trpD -0.0175
anthranilate Sase component I EC4.1.3.27 g1787518 trpE -0.0388
chorismate mutase/prephenate dehydrogenase EC5.4.99.5/EC1.3.1.12 g1788952 tyrA -0.2288
tyrosine aminotransferase EC2.6.1.5/EC2.6.1.57 g1790488 tyrB -1.1446
1.2 Histidine
EC5.3.1.16 g1788335 hisA 0.745
imidazoleglycerol-P dehydratase EC3.1.3.15/EC4.2.1.19 g1788333 hisB 0.4553
histidinol-P ATase EC2.6.1.9 g1788332 hisC 0.3143
histidinol dehydrogenase EC1.1.1.23 g1788331 hisD 0.6182
phosphoribosyl-AMP cyclohydrolase EC3.5.4.19/EC3.6.1.31 g1788337 hisIE 0.1308
cyclase g1788336 hisF 0.3994
ATP PRTase (hisG) EC2.4.2.17 g1788330 hisG 0.8779
Gln amidotransferase EC2.4.2.- g1788334 hisH 1.0118
"1.3 Aspartate family (lysine, methionine, threonine)"
Asp-semialdehyde DHase EC1.2.1.11 g1789841 asd 0.1041
Asn Sase EC6.3.1.1 g1790183 asnA 0.8979
asparagine synthetase B EC6.3.5.4 g1786889 asnB 0.7821
Asp ATase EC2.6.1.1 g1787159 aspC 0.7143
dehydrodipicolinate RDase EC1.3.1.26 g1786214 dapB -0.0008
tetrahydrodipicolinate N-succinyltransferase EC2.3.1.117 g1786362 dapD 1.3048
succinyl-diaminopimelate desuccinylase EC3.5.1.18 g1788816 dapE -0.6935
diaminopimelate epimerase EC5.1.1.7 g1790242 dapF -0.2948
diaminopimelate DCase EC4.1.1.20 g1789203 lysA -0.3019
aspartokinase III EC2.7.2.4 g1790455 lysC 0.277
homoserine O-succinyltransferase EC2.3.1.46 g1790443 metA 0.3597
cystathionine g-Sase g1790375 metB -0.151
b-cystahionase EC4.4.1.8 g1789383 metC 0.6525
tetrahydropteroyltriglutamate MTase EC2.1.1.14 g1790263 metE 0.8213
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase EC2.1.1.13 g1790450 metH 0.685
aspartokinase II/homoserine dehydrogenase II EC2.7.2.4 g1790376 metL 0.5505
aspartokinase-homoserine DHase EC2.7.2.4 g1786183 thrA -0.106
homoserine kinase EC 2.7.1.39 g1786184 thrB -0.4512
Thr Sase EC4.2.99.2 g1786185 thrC -0.024
1.4 Branched chain family (methionine)
"(isoleucine, isoleucine)"
"acetohydroxy acid synthase I, small subunit EC4.1.3.18" g1790104 ilvB -0.0118
dihydroxyacid dehydrase EC4.2.1.9 g1790206 ilvD 1.0471
branched-chain amino-acid aminotransferase EC2.6.1.42 g1790205 ilvE 1.1615
acetohydroxyl acid Sase II g1790203 ilvG 0.3773
acetolactate Sase III small chain EC4.1.3.18 g1786266 ilvH -1.1597
acetolactate Sase III large chain EC4.1.3.18 g1786265 ilvI -0.808
"acetohydroxy acid synthase II, small subunit EC4.1.3.18" g1790204 ilvM -1.06
"acetohydroxy acid synthase I, small subunit EC4.1.3.18" g1790103 ilvN 0.4548
valine--pyruvate aminotransferase EC2.6.1.66 g1789996 avtA -0.1376
(leucine)
a isopropylmalate Sase EC4.1.3.12 g1786261 leuA 0.6777
3-isopropylmalate DHase EC1.1.1.85 g1786260 leuB 0.4197
3-isopropylmalate dehydratase EC4.2.1.33 g1786259 leuC 0.8572
3-isopropylmalate dehydratase EC4.2.1.33 g1786258 leuD 0.5276
(Others)
threonine deaminase; threonine dehydratase biosynthetic EC4.2.1.16 g1790207 ilvA 0.4384
ketol acid reductoisomerase EC1.1.1.86 g1790210 ilvC 2.0352
lysine decarboxylase EC4.1.1.18 g1786384 ldcC -0.6752
1.5 Glutamate family
(arginine biosynthesis)
N-acetylglutamate synthase EC2.3.1.1 g1789181 argA -0.2615
N-acetylglutamate kinase EC2.7.2.8 g1790397 argB -0.087
N-acetyl-gamma-glutamyl-phosphate reductase EC1.2.1.38 g1790396 argC -0.2395
N-acetylornitine delta-aminotransferase EC2.6.1.11 g1789759 argD 0.1703
acetylornithine deacetylase EC3.5.1.16 g1790395 argE -0.76
ornithine carbamoyltransferase chain F EC2.1.3.3 g1786469 argF 0.4378
arginosuccinate Sase EC6.3.4.5 g1789563 argG 1.1416
arginosuccinate lyase EC4.3.2.1 g1790398 argH 0.5831
ornithine carbamoyltransferase EC2.1.3.3 g1790703 argI -0.4599
(polyamine biosynthesis)
? putrescine transport ATP-binding protein g1787079 potG 0.0125
arginine decarboxylase EC4.1.1.19 g1789307 speA 1.1242
agmatine ureohydrolase EC3.5.3.11 g1789306 speB 1.3329
ornithine decarboxylase EC4.1.1.17 g1789337 speC -0.7851
s-adenosylmethionine decarboxylase proenzyme EC4.1.1.50 g1786311 speD -0.2935
spermidine synthase g1786312 speE 0.1806
ornithine DCase EC4.1.1.17 g1786909 speF 0.0087
spermidine N1-acetyltransferase EC2.3.1.57 g1787867 speG -0.3581
(glutamate biosynthesis)
glutamate synthase (NADPH) large chain EC1.4.1.13/EC2.6.1.53 g1789605 gltB 0.8096
glutamate synthase (NADPH) small chain EC1.4.1.13/EC2.6.1.53 g1789606 gltD -0.9723
(glutamine biosynthesis)
Gln Sase EC6.3.1.2 g1790301 glnA 2.2493
(prorine biosynthesis)
g-glutamyl kinase EC2.7.2.11 g1786437 proB 0.4857
d-1-pyrroline-5-carboxylate RDase EC1.5.1.2 g1786585 proC -0.0189
(Others)
cyanate lyase (cyanate hydrolase) (cyanase) EC4.3.99.1 g1786535 cynS -0.1339
4-aminobutyrate aminotransferase EC2.6.1.19 g1789016 gabT 0.4826
probable ornithine aminotransferase EC2.6.1.13 g1789454 ygjG -0.366
"1.6 Serine family (Serine, Glycine, Cysteine)"
(serine)
D-3-phosphoglycerate DHase EC1.1.1.95 g1789279 serA 0.7549
phosphoserine phosphatase EC3.1.3.3 g1790849 serB 0.4273
phosphoserine ATase EC2.6.1.52 g1787136 serC 0.1235
(glycine)
Ser hydroxymethltrasferase glyA 2.251
(cysteine)
adenosine 5-phosphosulfate kinase EC2.7.1.25 g1789107 cysC -1.0304
ATP sulfurylase (ATP:sulfate adenyltransferase) EC2.7.7.4 g1789109 cysD 0.8744
Ser acethyltransferase EC2.3.1.30 g1790035 cysE 0.0571
siroheme synthesis g1789768 cysG -0.3035
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase EC2.8.2. g1789121 cysH 0.1037
sulfite reductase (NADPH) hemoprotein alpha subunit EC1.8.1.2 g1789122 cysI 0.6585
sulfite reductase (NADPH) flavoprotein beta subunit EC1.8.1.2 g1789123 cysJ 0.1777
Cys Sase EC4.2.99.8 g1788754 cysK 0.2617
ATP sulfurylase (ATP:sulfate adenyltransferase) subunit EC2.7.7.4 g1789108 cysN 0.4048
"2.Biosynthesis of cofactors, prosthetic groups, and carriers"
2.1 Biotin
"7,8-diamino-pelargonic acid ATase EC2.6.1.62" g1786991 bioA -0.2609
biotin synthesis prt g1786994 bioC -1.4048
dethiobiotin Sase EC6.3.3.3 g1786995 bioD -0.7791
7-keto-8-aminopelargonic acid Sase EC2.3.1.47 g1786993 bioF -0.5832
"biotin synthesis, block prior to pimeloyl CoA" g1789817 bioH -0.6793
biotin operon repressor/andbiotin-[acetyl-CoAcarboxylase]synthetase EC6.3.4.15 g1790408 birA -0.7468
biotin sulfoxid RDase EC1.-.-.- g1789973 bisC -0.283
2.2 Cobalamine (Vitamin B12)
COB(I) alamin adenosyltransferase EC2.5.1.17 g1787525 btuR -1.4688
cobalamin (5'-phosphate) synthase g1788301 cobS -0.9062
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase EC2.4.2.21 g1788300 cobT -0.9847
cobinamide kinase and guanylyltransferase g1788302 cobU -1.7632
ethanolamine ammonia-lyase heavy chain g1788782 eutB 0.7246
ethanolamine ammonia-lyase light chain EC4.3.1.7 g1788781 eutC 0.8849
2.3 Folic acid
"5,10-methylenetetrahydrofolate RDase EC1.7.99.5" g1790377 metF 0.2969
"5,10-methylenetetrahydrofolate RHase EC1.5.1.5" g1786741 folD 0.315
"7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase EC2.7.6.3" g1786335 folK -0.4288
aminodeoxychorismate lyase EC4.-.-.- g1787338 pabC -1.6724
dedA g1788656 dedA -0.287
"dihydrofolate RDase, type I EC1.5.1.3" g1786233 folA -0.7267
dihydropteroate Sase EC2.5.1.15 g1789567 folP -0.6405
folylpolyglutamate Sase EC6.3.2.17 g1788654 folC -0.246
GTP cyclohydrolase I EC3.5.4.16 g1788476 folE -0.0567
p-aminobenzoate Sase EC4.1.3.- g1788114 pabB -0.6792
2.4 Heme and porphyrin
glutamyl-tRNA reductase EC1.2.1.- g1787461 hemA -0.2852
delta-aminolevulinic acid dehydratase EC4.2.1.24 g1786566 hemB 0.2904
porphobilinogen deaminase EC4.3.1.8 g1790237 hemC -0.6387
uroporphyrinogen III synthase EC4.2.1.75 g1790236 hemD -1.1088
uroporphyrinogen decarboxylase EC4.1.1.37 g1790430 hemE 0.2346
coproporphyrinogen III oxidase EC1.3.3.3 g1788777 hemF -0.6824
ferrochelatase EC4.99.1.1 g1786681 hemH -0.3559
possibly protoporphyrinogen oxidase g1787463 hemK -0.6148
"glutamate-1-semialdehyde 2,1-aminomutase EC5.4.3.8" g1786349 hemL 0.6623
HemM protein g1787460 hemM -0.531
oxygen-independent coproporphyrinogen III oxidase EC1.-.-.- g1790298 hemN 0.4754
uroporphyrinogen III methylase EC2.1.1.107 g1790235 hemX 0.3114
HemY protein g1790234 hemY 0.0447
3-octaprenyl-4-hydroxybenzoate carboxy-lyase EC4.1.1.- g1788650 ubiX -1.0098
2.5 Lipoate
lipoate biosyn prt A =lipoic acid synthetase g1786846 lipA 0.7438
lipoate biosyn prt B g1786848 lipB -0.9965
2.6 Menaquinone and ubiquinone
menaquinone biosynthesis g1790365 menA -0.4564
dihydroxynaphthoic acid Sase EC4.1.3.36 g1788597 menB 2.155
4-(2'-carboxyphenyl0-4-oxybutyric acid Sase g1788596 menC -0.4413
"2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Sase" g1788599 menD -0.1237
O-succinylbenzoate-CoA EC6.2.1.26 g1788595 menE -0.5376
menaquinone biosynthesis protein meng g1790364 memG 0.6259
4-hydroxybenzoate-octaprenyl transferase EC2.5.1.- g1790473 ubiA -1.5162
flavin reductase EC1.6.8.- g1790278 ubiB -0.3883
chorismate lyase g1790472 ubiC -0.6316
3-demethylubiquinone-9 3-methyltransferase EC2.1.1.64 g1788564 ubiG -0.5065
EC1.14.13.- g1789274 ubiH -0.3122
2.7 Molybdopterin
molybdenum biosyn prt A g1786999 moaA 0.2187
molybdenum cofactor biosynthesis protein B g1787000 moaB 0.1446
molybdenum biosyn prt C g1787001 moaC 0.1753
"molybdopterin converting factor, sub 1" g1787002 moaD -0.5353
"molybdopterin converting factor, sub 2" g1787003 moaE -0.0272
biosynthesis of molybdopterin=molybdopterin-guanine dinucleotide biosynthesis g1790288 mobA -1.6314
molybdopterin biosynthesis g1787049 moeA 0.1155
molybdopterin biosynthesis g1787048 moeB -0.0026
molybdopterin biosynthesis Mog protein g1786190 mog -0.2344
2.8 Pantothenate
pantothenate metabolism flavoprotein g1790070 dfp -0.6415
pantothenate kinase EC2.7.1.33 g1790409 coaA -1.0604
converts alpha-ketoisovalerate to alpha-ketopantoate EC2.1.2.11 g1786326 panB 0.6672
pantoate--beta-alanine ligase EC6.3.2.1 g1786325 panC 0.1738
aspartate 1-decarboxylase EC4.1.1.11 g1786323 panD -0.1682
2.9 Pyridoxine (Vitamin B6)
pyridoxal phosphate biosynthetic protein PdxA g1786237 pdxA -0.7431
erythronate-4-phosphate dehydrogenase EC1.1.1.- g1788660 pdxB -0.5082
pyridoxamine phosphate oxidase EC1.4.3.5 g1787926 pdxH -0.5303
pyridoxal phosphate biosynthetic protein g1788917 pdxJ 1.0875
2.10 Nicotinate and nicotinamide (NAD)
nicotinate-nucleotide pyrophosphorylase EC2.4.2.19 g1786299 nadC -0.5709
NH3-dependent NAD synthetase EC6.3.5.1 g1788036 nadE -0.196
nicotinate phosphoribosyltransferase EC2.4.2.11 pncB -0.2253
2.11 Quinolinate (NAD)
quinolinate synthetase A protein g1786964 nadA -0.939
l-aspartate oxidase (quinolinate synthetase B) EC1.4.3.16 g1788928 nadB -0.8046
2.12 Riboflavin
GTP cyclohydrolase II EC3.5.4.25 g1787533 ribA 0.0425
"3,4-dihydroxy-2-butanone 4-P Sase" g1789420 ribB 0.5668
riboflavin biosynthesis protein g1786616 ribD -0.8384
probable riboflavin synthase beta chain EC2.5.1.9 g1786617 ribH 1.5523
2.13 Thiamin
thiamine biosynthesis g1790427 thiC 0.2342
thiamine biosynthesis g1790426 thiE -0.8181
thiamine biosynthesis g1790425 thiF -1.1097
thiamine biosynthesis g1790424 thiG -0.2781
thiamine biosynthesis g1790423 thiH -0.6186
(4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis g1786626 thiJ) 0.4719
"2.14 Thioredoxin, glutaredoxin, and glutathione"
gamma-glutamyltranspeptidase EC2.3.2.2 g1789856 ggt -0.3033
glutaredoxin 2 g1787303 grxB -0.2953
glutaredoxin 3 (grx3) g1790039 grxC 0.5399
(gamma-glutamylcysteine synthetase EC6.3.2.2 g1789044 gshA) 0.1602
glutathione synthetase EC6.3.2.3 g1789316 gshB 0.6793
glutathione s-transferase EC2.5.1.18 g1787923 gst -0.0811
glutathione RDase EC1.6.4.2 g1789915 gor 0.8473
thioredoxin g1790215 trxA 0.3625
3. Cell envelope
"3.1 Membranes, lipoproteins, and porins"
(Outer membrane)
outer membrane porin protein g1786765 nmpC 1.1106
outer membrane prt P5 g1787191 ompA 2.8216
outer membrane protein F g1787160 ompF 1.6839
outer membrane protein C g1788544 ompC 2.6938
outer membrane protein X g1787034 ompX 2.2185
outer membrane pore protein E g1786436 phoE -0.3608
(Lipoproteins)
15kD peptidoglycan-assoc lpp=major outer membrane lipoprotein g1787967 lpp 2.3447
lipoprotein-28 g1790093 nlpA -1.3837
lipoprotein-34 g1788822 nlpB 0.9912
probable lipoprotein g1788001 nlpC -0.7569
lpp g1789099 nlpD -0.5705
rare lppA g1786852 rlpA -0.7776
rare lppB g1786860 rlpB 0.2286
apolipoprotein N-acyltransferase EC2.3.1.- g1786878 lnt 0.3172
prolipoprotein diacylglyceryl Tase EC2.4.99.- g1789192 lgt 0.5437
osmotically inducible lipoprotein B g1787539 osmB -0.967
peptidoglycan-associated lipoprotein g1786962 pal 2.6299
VacJ lipoprotein g1788688 vacJ -0.0105
(Others)
inner membrane protein g1790862 creD -0.948
membrane associated protein g1787901 gusC -1.6284
peripheral membrane protein U g1790161 phoU 1.3821
3.2 Murein sacculus and peptidoglycan
"Ala racemase, biosynthetic EC5.1.1.1" g1790487 alr -0.1844
probable n-acetylmuramoyl-l-alanine amidase EC3.5.1.28 g1788776 amiA -0.4289
N-acetylmuramoyl-L-Ala amidase EC3.5.1.28 g1790611 amiB -0.5943
"D-alanyl-D-Ala carboxypeptidase, fraction B EC3.4.16.4" g1789573 dacB -0.6873
penicillin-binding protein 6 g1787062 dacC 0.3076
D-alanine--D-alanine ligase A EC6.3.2.4 g1786579 ddlA 0.0141
D-Ala-D-Ala ligase EC6.3.2.4 g1786280 ddlB -0.483
penicillin tolerance and control of the stringent response g1786212 lytB 0.9776
membrane-bound lytic murein transglycosylase A EC3.2.1.- g1789179 mltA 0.639
membrane-bound lytic transglycosylase B EC3.2.1.- g1789053 mltB 0.1107
peptidoglycan synthetase; cell wall synthesis g1789799 mrcA 0.3603
"penicillin-BP 1B alternate gene names ponB, pbpF" 1725 mrcB 0.5249
(PBP2 g1786854 mrdA) 0.3729
rod shape-determining protein rodA g1786853 mrdB -0.4145
phospho-N-acetylmuramoyl-pentapeptide Tase E EC2.7.8.13 g1786275 mraY 0.7708
rod shape-determining prt g1789649 mreB 1.1919
rod shape-determining prt g1789648 mreC 0.1898
rod shape-determining prt g1789647 mreD -1.1542
udp-n-acetylglucosamine 1-carboxyvinyltransferase EC2.5.1.7 g1789580 murA 0.8947
UDP-NAc-enolpyruvoylglucosasmine RDase EC1.1.1.158 g1790407 murB -1.4896
UDP-MurNAc-Ala ligase EC6.3.2.8 g1786279 murC 0.3312
UDP-MurNAc-Ala-D-Glu ligase EC6.3.2.9 g1786276 murD 0.0701
UDP-MurNAc-pentapeptide Sase=D-alanyl:D-alanine-adding enzyme g1786274 murF 0.2633
UDP-MurNAc-tripeptide Sase g1786273 murE 0.2221
GlcNAc transferase g1786278 murG -0.2342
glutamate racemase EC5.1.1.3 g1790406 murI -0.7947
penicillin-binding protein 7 precursor (pbp-7) g1788455 pbpG -0.3155
soluble lytic murein transglycosylase EC3.2.1.- g1790853 slt -0.5004
"3.3 Surface polysaccharides, lipopolysaccharides and antigens"
phosphoheptose isomerase g1786416 gmhA 1.0689
2-dehydro-3-deoxyphosphooctonate aldolase EC4.1.2.16 g1787466 kdsA 1.0284
CTP:CMP-3-deoxy-D-manno-octulosonate-cytidylyl-transferase EC2.7.7.38 g1787147 kdsB -0.3767
3-deoxy-D-manno-octulosonic-acid Tase EC2.-.-.- g1790064 kdtA -0.0952
UDP-GlcNAc acethyltransferase EC2.3.1.129 g1786378 lpxA 0.2384
lipid A disaccharide Sase g1786379 lpxB -0.5034
udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase g1786285 lpxC 0.6677
periplasmic glucans biosynthesis protein g1787286 mdoG 0.014
EC2.4.1.- g1790058 rfaB -2.0098
lipopolysaccharide heptosyltransferase-1 g1790051 rfaC -1.5519
ADP-L-glycero-D-mannoheptose-6-epimerase EC5.1.3.- g1790049 rfaD 1.6481
ADP-heptose-lps heptosyltransferase II g1790050 rfaF -0.5273
glucosyltransferase I g1790061 rfaG -2.0594
EC2.4.1.44 g1790057 rfaI -2.1583
UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase EC2.4.1.58 g1790056 rfaJ -2.4799
"lipopolysaccharide 1,2-n- acetylglucosaminetransferase EC2.4.-.-" g1790053 rfaK -2.2763
Lipopolysaccharide core biosynthesis; phosphorylationofcoreheptose g1790060 rfaP -1.7286
lipopolysaccharide core biosynthesis g1790062 rfaQ -1.5972
lipopolysaccharide core biosynthesis g1790059 rfaS -2.612
lipopolysaccharide core biosynthesis g1790055 rfaY -1.3239
lipopolysaccharide core biosynthesis g1790054 rfaZ -1.781
TDP-glucose pyrophosphorylase EC2.7.7.24 g1788351 rfbA -0.9452
"dtdp-glucose 4,6-dehydratase EC4.2.1.46" g1788353 rfbB -1.2725
"dTDP-4-dehydrorhamnose 3,5-epimerase EC5.1.3.13" g1788350 rfbC -2.4584
putative o-antigen transporter g1788349 rfbX -2.4052
o-antigen polymerase g1788347 rfc -2.5355
rfe prt g1790218 rfe -0.3377
UDP-ManNAc dehydrogenase g1790221 rrfD -0.2605
UDP-N-acetylglucosamine epimerase (UDP-GlcNAc-2-epimerase) g1790223 rffG 0.7472
probable UDP-N-acetyl-D-mannosaminuronic acid transferase g1790229 rffM -0.1769
biosynthesis of enterobacterial common antigen EC2.4.1.- g1790228 rffT -0.4654
GDP-d-mannose dehydratase g1788366 yefA 1.554
3.4 Surface structures
(Fimbriae)
adhesin B precursor=type 1 fimbrial subunit g1790769 fimA 0.8613
outer membrane usher protein g1790772 fimD_2 -1.352
outer membrane usher protein g1786332 htrE -1.2321
regulation of length and mediation of adhesion of type1 fimbriae g1790773 fimF -1.5611
regulation of length and mediation of adhesion of type1 fimbriae g1790774 fimG -1.1686
regulation of length and mediation of adhesion of type1 fimbriae g1790775 fimH -1.5398
fimbriae Z protein g1786747 fimZ -2.0375
(Flagella)
flagellar basal body P-ring protein g1787312 flgA -1.2711
putative flagellar basal-body rod protein g1787313 flgB -0.637
putative flagellar basal-body rod protein g1787314 flgC -0.6731
flagellar hook formation protein g1787315 flgD -0.3835
flagellar hook protein g1787316 flgE 0.5274
putative flagellar basal-body rod protein (proximal rod protein) g1787317 flgF -0.625
flagellar basal-body rod protein (distal rod protein) g1787318 flgG 0.1103
flagellar L-ring protein precursor g1787319 flgH -0.3764
flagellar P-ring protein precursor g1787320 flgI -0.6713
flagellar protein g1787321 flgJ -0.3292
flagellar hook-associated protein 1 g1787323 flgK -0.0977
flagellar hook-associated protein 3 g1787324 flgL -0.2398
flagella synthesis protein g1787310 flgN -1.1673
flagellar biosynthesis protein g1788187 flhA -0.8665
flagellin g1788232 fliC 1.0158
flagellar hook associated protein 2 g1788233 fliD -0.6706
flagellar hook-basal body complex protein g1788247 fliE -0.6752
flagellar basal-body M-ring protein g1788248 fliF -0.2424
flagellar motor switch protein g1788249 fliG 0.1515
flagellar biosynthesis g1788250 fliH -0.9546
flagellum-specific ATP synthase EC3.6.1.34 g1788251 fliI -0.2873
flagellar FliJ protein g1788252 fliJ -1.2063
(hook-length control protein g1788253 fliK) -0.7553
flagellar biosynthesis g1788254 fliL -0.4569
(flagellar motor switch protein g1788255 fliM) 0.0701
(flagellar motor switch protein g1788256 fliN) 0.2007
flagellar synthesis g1788258 fliO -1.0395
flagellar biosynthetic protein g1788259 fliP -0.0184
flagellar biosynthetic protein g1788260 fliQ -1.2783
flagellar biosynthetic protein g1788261 fliR -0.4949
flagellar synthesis g1788234 fliS -1.4632
flagellar synthesis g1788235 fliT -1.0831
FliY protein precursor g1788228 fliY 0.7922
FliZ protein g1788230 fliZ -0.9378
motility protein A g1788199 motA -0.3112
motility protein B g1788198 motB -1.0154
4. Cellular processes
4.1 General
chemotaxis protein CheA EC2.7.3.- g1788197 cheA -0.7061
protein-glutamate methylesterase EC3.1.1.61 g1788192 cheB -0.224
chemotaxis protein methyltransferase EC2.1.1.80 g1788193 cheR -0.2432
purine binding chemotaxis protein g1788196 cheW -0.5645
chemotactic signal transduction g1788191 cheY -0.7478
chemotactic signal transduction g1788190 cheZ -1.0139
haemolysin expression modulating protein g1786665 hha -0.8242
chemotaxis protein IV g1788194 tap -0.5747
methyl-accepting chemotaxis protein I g1790815 tsr 0.0958
methyl-accepting chemotaxis protein II g1788195 tar -0.5202
methyl-accepting chemotaxis protein III g1787690 trg -1.2944
4.2 Cell division
cytoplasmic axial filament prt g1789645 cafA 0.1474
division inhibition protein g1787857 dicB -1.7976
filamentation in presence of cyclic AMP in mutant g1789761 fic -0.1771
cell division prt g1786282 ftsA -0.4512
cell division ATP-BP g1789873 ftsE 0.1278
penicillin-BP 3 g1786272 ftsI 0.0305
cell division prt g1789569 ftsJ -0.1505
cell division protein g1787117 ftsK -0.1809
cell division prt g1786271 ftsL -1.1704
cell division protein ftsn g1790368 ftsN -0.2387
cell division prt g1786281 ftsQ -0.7429
cell division prt g1786277 ftsW 0.2459
cell division membrane prt g1789872 ftsX -0.2145
cell division prt g1789874 ftsY 0.4534
cell division prt g1786284 ftsZ 1.3791
cell division protein ftsh EC3.4.24.- g1789568 hflB 1.4165
probable cell division role g1787785 hipA -1.5776
cell cycle protein g1786386 mesJ -1.2041
cell division inhibitor g1787424 minC -0.8429
cell division inhibitor g1787423 minD -0.4056
cell division topological specificity factor g1787422 minE -0.559
cell division inhibitor g1787192 sulA -1.5768
4.3 Cell killing
KicA protein g1787153 mukE 0.1561
killing factor KicB g1787152 mukF 0.2097
4.4 Chaperones
chaperone protein g1786333 ecpD -1.3537
heat shock prt g1786197 dnaJ 0.9254
heat shock prt 70 g1786196 dnaK 2.3653
chaperone protein involved in biogenesis of type 1 fimbriae g1790771 fimC -1.6488
heat shock protein; phage lambda replication; host DNA synthesis g1788967 grpE 1.0982
heat-responsive regulatory protein EC2.7.1.69 g1786951 hrsA -0.7015
heat shock prt C62.5 g1786679 htpG 2.0808
heat shock prt groEL g1790586 mopA 3.1717
heat shock prt groES g1790585 mopB 1.1167
4.5 Detoxification
arsenate reductase (arsenical pump modifier) g1789918 arsC -0.0457
catalase HPII EC1.11.1.6 g1788027 katE -0.1193
catalase hydroperoxidase I EC1.11.1.6 g1790378 katG 1.4895
manganese superoxide dismutase EC1.15.1.1 g1790342 sodA 2.3208
superoxide dismutase EC1.15.1.1 g1787946 sodB 1.1227
copper-zinc superoxide dismutase EC1.15.1.1 g1787934 sodC -0.2679
4.6 thiophene and furan oxidation g1790141 thdF 0.1083
4.7 Protein and peptide secretion
putative general secretion pathway protein b g1789720 yheD -1.8865
putative general secretion pathway protein c g1789721 yheE -1.8458
putative general secretion pathway protein d g1789722 yheF -0.4857
putative general secretion pathway protein e g1789723 yheG -0.9802
protein transport protein g1786296 hofB -0.986
protein transport protein g1786295 hofC -1.0489
protein transport protein hofq precursor g1789793 hofQ -1.2848
putative general secretion pathway protein f g1789724 hofF -1.1891
putative general secretion pathway protein g g1789725 hofG -0.935
putative general secretion pathway protein h g1789726 hofH -1.6429
putative general secretion pathway protein i g1789727 yheH -1.1119
putative general secretion pathway protein j g1789728 yheI -1.6983
putative general secretion pathway protein k g1789729 yheJ -1.1943
putative general secretion pathway protein l g1789730 yheK -1.1704
putative general secretion pathway protein m g1789731 pshM -1.2298
lpp signal peptidase EC3.4.23.36 3.4.23.36 lspA 0.0677
peptide transport system ATP-BP g1787547 sapF -0.6429
preprotein translocase g1790413 secE 0.534
preprotein translocase secy subunit g1789696 prlA 0.414
protein-export membrane prt g1786609 secD 1.0525
protein-export membrane prt g1786610 secF 0.7788
protein-export membrane prt g1789565 secG -0.0549
protein-export prt g1790038 secB 1.6859
preprotein translocase sub g1786287 secA 1.6357
trigger factor g1786640 tig 2.4251
5.Central intermediary metabolism
5.1 Phosphorus compounds
inorganic PPase EC3.6.1.1 g1790673 ppa 2.1357
polyphosphate kinase EC2.7.4.1 g1788847 ppk -0.0673
lysophospholipase L2 EC3.1.1.5 g1790259 pldB -0.7563
exopolyphosphatase ppx 695 -0.4786
5.2 Polysaccharides - (cytoplasmic)
glycogen Sase EC2.4.1.21 g1789836 glgA -0.3207
"1,4-glucan brancing enzyme EC2.4.1.18" g1789839 glgB 0.1814
ADP-glucose Sase EC1.7.7.27/EC2.7.7.27 g1789837 glgC 0.6081
a-glucan phosphorylase EC2.4.1.1 g1789835 glgP 0.5145
glycogen synthesis g1789428 glgS -0.4316
glycogen operon prt EC3.2.1.- g1789838 glgX -0.8117
alpha trehalose phosphate synthase EC2.4.1.15 g1788206 otsA -0.5817
trehalose phosphatase EC3.1.3.12 g1788207 otsB -1.3073
mannose-1-phosphate guanylyltransferase (gdp) g1788362 cpsB 0.1487
phosphomannomutase EC5.4.2.8 g1788361 cpsG 0.1761
5.3 Sulfur metabolism
arylsulfatase regulatory prt EC3.1.6.1 g1790233 aslA 0.4085
arylsulfatase regulatory prt g1790232 aslB -0.7344
5.4 Other Central.
(isocitrate dehydrogenase kinase/phosphatase EC 2.3.1.46 g1790446 aceK) -0.2071
7-a-hydroxysteroid DHase EC1.1.1.159 g1787905 hdhA -0.3138
glucose dehydrogenase EC1.1.99.17 g1786316 gcd 0.6803
glyoxylate carboligase EC4.1.1.47 g1786717 gcl 0.7519
glycolate oxidase subunit g1789351 glcD -0.0983
glycolate oxidase subunits GlcE and GlcF g1789350 glcE/glcF -0.6511
"alanine racemase, catabolic precursor EC5.1.1.1" g1787439 dadX -0.6997
glycine acetyltransferase EC2.3.1.29 g1790046 kbl 1.2037
probable pyruvate formate-lyase 2 activating enzyme EC1.97.1.4 g1790389 pflC -0.5788
formate acetyltransferase 2 (pyruvate formate-II) EC2.3.1.54 g1790388 pflD -0.1182
threonine 3-dehydrogenase EC1.1.1.103 g1790045 tdh 0.9217
catabolic threonine dehydratase EC4.2.1.16 g1789505 tdcB -0.2348
tartrate dehydratse EC4.2.1.32 g1789442 ttdA -0.3178
tartrate dehydratse EC4.2.1.32 g1789443 ttdB 0.9225
putative l-serine dehydratase part 2 EC4.2.1.13 g1789498 yhaP 0.5259
putative l-serine dehydratase part 1 EC4.2.1.13 g1789500 yhaQ -1.8684
probable formate acetyltransferase 3 EC2.3.1.54 g1789502 yhaS 0.7188
6. Energy metabolism
6.1 Respiratory chain I (Dehydrogenases)
D-amino acid dehydrogenase g1787438 dadA -0.1763
D-lactate DHase EC1.1.1.28 (Aerobic) g1788454 dld 0.2071
DMSO RDase A (Anaerobic) g1787121 dmsA 0.5339
DMSO RDase B (Anaerobic) g1787122 dmsB 0.6067
DMSO RDase C (Anaerobic) g1787123 dmsC -0.1666
formate DHase-N affector g1790329 fdhD -1.0755
formate DHase pathway prt g1790324 fdhE 0.4386
formate dehydrogenase-H alpha subunit EC1.2.1.2 (Anaerobic) g1790516 fdhF -0.5941
formate DHase EC1.2.1.2 g1787748 fdnG 1.0524
gamma subunit of formate dehydrogenase N g1787750 fdnI 0.5833
beta subunit of formate dehydrogenase N g1787749 fdnH 0.8884
formate DHase-O a sub EC1.2.1.2 (Anaerobic) g1790327 fdoG 0.5857
formate DHase-O b sub EC1.2.1.2 (Anaerobic) g1790326 fdoH 0.4848
formate DHase-O g sub EC1.2.1.2 (Anaerobic) g1790325 fdoI 0.4849
"G3PD, sub A EC1.1.99.5 (Anaerobic)" g1788574 glpA 0.2254
"G3PD, sub B EC1.1.99.5 (Anaerobic)" g1788575 glpB -0.5819
"G3PD, sub C EC1.1.99.5 (Anaerobic)" g1788576 glpC 0.0937
glycerol-3-phosphate dehydrogenase EC1.1.99.5 (Aerobic) g1789832 glpD 0.3674
glycerol-3-P DHase EC1.1.1.8 (Aerobic) g1790037 gpsA -0.4036
hydrogenase-1 small chain EC1.18.99.1 g1787206 hyaA -0.1085
hydrogenase-1 large chain (nifE hydrogenase) EC1.18.99.1 g1787207 hyaB 0.1839
probable Ni/Fe-hydrogenase 1 b-type cytochrome g1787208 hyaC 0.3621
hydrogenase-2 small subunit EC1.18.99.1 (Aerobic) g1789370 hybA 1.0786
probable hydrogenase-2 cytochrome b subunit g1789369 hybB 1.0316
hydrogenase-2 large subunit EC1.18.99.1 (Aerobic) g1789368 hybC 1.4382
formate hydrogenlyase subunit 2 (Anaerobic) g1789079 hycB 0.0455
formate hydrogenlyase subunit 3 (Anaerobic) g1789078 hycC -0.7866
formate hydrogenlyase subunit 4 (Anaerobic) g1789077 hycD 1.1128
formate hydrogenlyase subunit 5 (Anaerobic) g1789076 hycE -0.7834
formate hydrogenlyase subunit 6 (Anaerobic) g1789075 hycF 0.4995
formate hydrogenlyase subunit 7 (Anaerobic) g1789074 hycG 0.2963
formate hydrogenlyase maturation protein g1789073 hycH -0.1547
hydrogenase isoenzymes formation protein g1789082 hypB 0.321
hydrogenase isoenzyme formation prt (Anaerobic) g1789083 hypC -0.962
hydrogenase isoenzymes formation protein g1789084 hypD 0.1055
hydrogenase isoenzymes formation protein HypE g1789085 hypE 0.4903
D-lactate dehydrogenase EC1.1.1.28 (Aerobic) ldhA 0.9094
NADH DHase EC1.6.99.3 (Aerobic) g1787352 ndh 0.5756
NADH dehydrogenase I chain A EC1.6.5.3 (Aerobic) g1788625 nuoA 0.1772
NADH dehydrogenase I chain B EC1.6.5.3 (Aerobic) g1788624 nuoB 0.5664
"NADH dehydrogenase I chain C,D EC1.6.5.3 (Aerobic)" g1788622 "nuoC,D" 1.1972
NADH dehydrogenase I chain E EC1.6.5.3 (Aerobic) g1788621 nuoE 0.7651
NADH dehydrogenase I chain F EC1.6.5.3 (Aerobic) g1788620 nuoF 1.1821
NADH dehydrogenase I chain H EC1.6.5.3 (Aerobic) g1788618 nuoH 1.4786
NADH dehydrogenase I chain J EC1.6.5.3 (Aerobic) g1788616 nuoJ 0.786
NADH dehydrogenase I chain L EC1.6.5.3 (Aerobic) g1788614 nuoL 1.4758
NADH dehydrogenase I chain M EC1.6.5.3 (Aerobic) g1788613 nuoM 0.9225
NADH dehydrogenase I chain N EC1.6.5.3 (Aerobic) g1788612 nuoN 1.1361
pyruvate dehydrogenase EC1.2.2.2 (Aerobic) g1787096 poxB -0.451
"6.2 Respiratory chain II (Electron transport, Oxidases)"
(cytochrome)
probable cytochrome oxidase subunit I EC1.10.3.- g1787212 appC -0.1615
probable cytochrome oxidase subunit II EC1.10.3.- g1787213 appB -0.5628
cytochromec-type prt g1787230 torC -0.1136
cytochrome c-type protein g1788530 napC 0.6194
cytochrome c-type protein g1788531 napB 0.5111
cytochrome b562 g1790684 cybC -0.1414
cytochrome oxidase sub I EC1.10.3.- g1786953 cydA 1.0134
cytochrome oxidase sub II EC1.10.3.- g1786954 cydB 1.9042
cytochrome o ubiquinol oxidase subunit II EC1.10.3.- g1786635 cyoA 0.2729
cytochrome o ubiquinol oxidase subunit I EC1.10.3.- g1786634 cyoB 1.2577
cytochrome o ubiquinol oxidase subunit III EC1.10.3.- g1786633 cyoC 1.3835
cytochrome o ubiquinol oxidase C subunit g1786632 cyoD 0.815
cytochrome o ubiquinol oxidase C subunit g1786631 cyoE -0.299
(cytochrome c-type biogenesis)
cytochrome c-type biogenesis protein g1788525 ccmE -0.0636
cytochrome c-type biogenesis protein g1788524 ccmF 0.283
cytochrome c-type biogenesis protein g1788522 ccmH -0.142
cytochrome c-type biogenesis g1790579 cutA -0.8424
cytochrome c-type biogenesis protein g1790511 nrfE -0.6836
cytochrome c-type biogenesis protein g1790512 nrfF -0.8441
(fumarate reductase)
(nitrate reductase)
probable nitrate reductase ECEC1.7.99.4 (Anaerobic) g1788534 napA 1.6828
respiratory nitrate reductase 1 alpha chain EC1.7.99.4 (Anaerobic) g1787477 narG 1.4795
respiratory nitrate reductase 1 beta chain EC1.7.99.4 (Anaerobic) g1787478 narH 1.7086
respiratory nitrate reductase 1 delta chain EC1.7.99.4 (Anaerobic) g1787479 narJ 0.3406
respiratory nitrate reductase 1 gamma chain EC1.7.99.4 (Anaerobic) g1787480 narI 1.4906
respiratory nitrate reductase 2 gamma chain EC1.7.99.4 (Anaerobic) g1787738 narV -0.5538
respiratory nitrate reductase 2 delta chain EC1.7.99.4 (Anaerobic) g1787739 narW -0.5833
respiratory nitrate reductase 2 beta chain EC1.7.99.4 (Anaerobic) g1787740 narY 0.3843
respiratory nitrate reductase 2 alpha chain EC1.7.99.4 (Anaerobic) g1787741 narZ 0.0611
NADH-nitrate oxidoreductase apoprotein EC1.6.6.4 (Anaerobic) g1789765 nirB 1.5157
NADH-nitrate reductase activity EC1.6.6.4 (Anaerobic) g1789767 nirC 1.1963
nitrite reductase (nad(p)h) small subunit EC1.6.6.4 (Anaerobic) g1789766 nirD 0.9599
formate-dependent nitrite RDase (Anaerobic) g1790506 nrfA 0.5868
formate-dependent nitrite RDase (Anaerobic) g1790507 nrfB -0.2299
formate-dependent nitrite RDase prt Fe-S centers (Anaerobic) g1790508 nrfC 0.025
formate-dependent nitrite RDase transmembrane prt (Anaerobic) g1790509 nrfD -0.0565
(TMANO reductase)
trimethylamine-N-oxide reductase EC1.6.6.9 g1787231 torA 0.1686
(peroxidases)
thiol peroxidase g1787584 tpx 1.7656
(Ferredoxin)
ferredoxin g1788874 fdx 0.8491
flavodoxin g1786900 fldA 0.7201
flavodoxin II g1789262 fldB 0.3405
ferredoxin--NADP reductase EC1.18.1.2 g1790359 fpr -1.1956
ferredoxin-type protein g1788536 napF -0.5103
ferredoxin-type protein g1788532 napH -0.256
ferredoxin-type protein g1788533 napG -0.1707
(Others)
thiol:disulfide interchange protein g1788523 dsbE -0.3907
thiol:disulfide interchange protein (c-type cytochrome) g1790578 dsbD -0.7894
thiol:disulfide interchange protein g1789260 dsbC -0.3185
pyridine nucleotide transhydrogenase sub a EC1.6.1.1 g1787887 pntA -0.1832
pyridine nucleotide transhydrogenase sub b EC1.6.1.1 g1787886 pntB 0.822
probable cytochrome c peroxidase EC1.11.1.5 g1789935 yhjA -0.7489
6.3 ATP-proton motive force interconversion
ATP Sase F1 a sub EC3.6.1.34 g1790172 atpA 2.5668
ATP Sase F0 a sub EC3.6.1.34 g1790176 atpB 0.8371
ATP Sase F1 e sub EC3.6.1.34 g1790169 atpC 0.6746
ATP Sase F1 b sub EC3.6.1.34 g1790170 atpD 2.5965
ATP Sase C chain g1790175 atpE 1.6834
ATP Sase F0 b sub EC3.6.1.34 g1790174 atpF 0.8293
ATP Sase F1 g sub EC3.6.1.34 g1790171 atpG 1.2183
ATP Sase F1 d sub EC3.6.1.34 g1790173 atpH -0.1102
ATP synthase subunit? g1790177 atpI -0.9742
6.4 Catabolism of Carbohydrates (General)
(Entner-Doudoroff)
2-keto-3-deoxy-6-phosphogluconate 6-P aldolase EC4.1.2.14/EC4.1.3.16 g1788156 eda 2.1997
6-phosphogluconate dehydratase EC4.2.1.12 g1788157 edd 0.1283
(Gluconeogenesis)
phosphoenolpyruvate carboxykinase EC4.1.1.49 g1789807 pckA 1.4847
(Glycolysis)
glucose-1-phosphatase precursor (g1pase) g1787237 agp -0.0482
enolase EC4.2.1.11 g1789141 eno 3.2973
fructose-bisphosphate aldolase EC4.1.2.13 g1789293 fba 2.9202
1-phosphofructokinase EC2.7.1.56 g1788493 fruK 0.1382
glyceraldehyde 3-phosphate dehydrogenase A EC1.2.1.12 g1788079 gapA 3.0829
glyceraldehyde 3-phosphate dehydrogenase C EC1.2.1.12 g1787686 gapC -0.0388
glucose kinase EC2.7.1.2 g1788732 glk -0.7148
phosphoglyceromutase EC5.4.2.1 g1786970 gpmA 1.687
phosphoglucomutase EC5.4.2.2 g1786904 pgm 1.6786
phosphoglycerate kinase EC2.7.2.3 g1789294 pgk 2.5845
6-phosphofructokinase EC2.7.1.11 g1790350 pfkA 2.3873
6-phosphofructokinase isozyme EC2.7.1.11 g1788017 pfkB -0.6438
glucose-6-P isomerase EC5.3.1.9 g1790457 pgi 1.6262
pyruvate kinase type II EC2.7.1.40 g1788160 pykA 0.7058
pyruvate kinase EC2.7.1.40 g1787965 pykF 2.2065
triosephosphate isomerase EC5.3.1.1 g1790353 tpiA 2.4897
"putative 2,3-bisphosphoglycerate-independent phosphoglycerate " g1790041 yibO 1.6066
(Pentose phosphate pathway)
6-phosphogluconate DHase EC1.1.1.44 g1788340 gnd 1.6413
ribose 5-phosphate isomerase EC5.3.1.6 g1789280 rpiA 0.8403
transaldolase B EC2.2.1.2 g1786189 talB 2.1603
transaldolase-like protein EC2.2.1.- g1790382 talC 0.2232
transketolase 1 EC2.2.1.1 g1789303 tktA 2.5055
transketolase 2 EC2.2.1.1 g1788808 tktB 0.0693
glucose 6-phosphate 1 dehydrogenas EC1.1.1.49 g1788158 zwf 0.6331
(TCA cycle)
(isocitrate lyase EC4.1.3.1 (Glyoxylate Bypass of TCA) g1790445 aceA) 1.268
(malate synthase A EC4.1.3.2 (Glyoxylate Bypass of TCA) g1790444 aceB) -0.3062
pyruvate DHase EC1.2.4.1 g1786304 aceE 2.4506
dihydrolipoamide acetyltransferase EC2.3.1.12 g1786305 aceF 2.1666
"aconitate hydratase 1 (citrate hydro-lyase 1) EC4.2.1.3 (Anaerobic, Aerobic)" g1787531 acnA -0.4348
malate synthase EC4.1.3.2 (Glyoxylate Bypass of TCA) g1789348 glcB 0.3605
"citrate synthetase (Aerobic, Anaerobic)" g1786939 gltA 1.6826
fumarate RDase 13kD hydrophobic prt EC1.3.99.1 (Anaerobic) g1790594 frdD 0.8026
fumarate RDase flavoprotein sub EC1.3.99.1 (Anaerobic) g1790597 frdA 1.6567
fumarate RDase iron-sulfur prt EC1.3.99.1 (Anaerobic) g1790596 frdB 1.2217
fumarate RDase EC1.3.99.1 (Anaerobic) g1790595 frdC 0.2821
fumarate hydratase class i (fumarase) EC4.2.1.2 (Anaerobic) g1790564 fumB 0.9039
isocitrate dehydrogenase EC1.1.1.42 g1787381 icdA 1.7643
lipoamide DHase EC1.8.1.4 g1786307 lpdA 2.4327
phosphoenol pyruvate carboxylase EC4.1.1.31 (Glycerate bypass of TCA) g1790393 ppc 0.6118
succinate dehydrogenase flavoprotein subunit EC1.3.99.1 (Aerobic) g1786942 sdhA 1.5892
succinate dehydrogenase iron-sulfur protein EC1.3.99.1 (Aerobic) g1786943 sdhB -0.3058
succinate dehydrogenase cytochrome b-556 subunit (Aerobic) g1786940 sdhC -1.0176
succinate dehydrogenase 13 kD hydrophobic protein (Aerobic) g1786941 sdhD 0.3942
NAD-linked malic enzyme; malate oxidoreductase EC1.1.1.38 g1787754 sfcA 0.2308
2-oxoglutarate DHase EC1.2.4.2 (Aerobic) g1786945 sucA 1.4356
dihydrolipoamide succinyltransferase (Aerobic) g1786946 sucB 2.0848
"succinyl-CoA Sase b sub EC6.2.1.5 (Aerobic, Anaerobic)" g1786948 sucC 1.4043
"succinyl-CoA Sase a sub EC6.2.1.5 (Aerobic, Anaerobic)" g1786949 sucD 2.2288
"fumarate hydratase class I"" EC4.2.1.2 (Aerobic)" g1787897 fumA 0.1486
fumarate hydratase EC4.2.1.2 (Aerobic) g1787896 fumC -0.2077
"malate DHase EC1.1.1.37 (Aerobic, Anaerobic)" g1789632 mdh 1.7353
(Terminal reaction of Glycolysis: pyrumate and acetyl-CoA metabolism for Synechocystis)
acetate kinase EC2.7.2.1 (Anaerobic > Aerobic) g1788633 ackA 2.0209
acetyl-CoA sythetase EC6.2.1.1 g1790505 acs 0.9457
alcohol/acetaldehyde dehydrogenase EC1.1.1.1 g1787493 adhE 2.1504
formate acetyltransferase 1 EC2.3.1.54 (Anaerobic > Aerobic) g1787131 pflB 3.0429
phosphoenolpyruvate synthase EC2.7.9.2 g1787994 ppsA 0.9979
phosphate acetyltransferase EC2.3.1.8 (Anaerobic > Aerobic) g1788635 pta 2.5013
6.5 Catabolism of Carbohydrates (Specific)
(Amino sugars)
Gln amidotransferase (C) g1790167 glmS 1.537
GlcAc-6-P deacetylase EC3.5.1.25 (C) g1786892 nagA 0.5449
glucosamine-6-P deaminase EC5.3.1.10 (C) g1786893 nagB 1.2947
putative galactosamine-6-phosphate isomerase EC5.3.1.- g1789530 yhbU -0.0186
(Carboxylates)
tagatose-bisphosphate aldolase g1789526 agaY -0.1824
putative tagatose 6-phosphate kinase agaz EC2.7.1.- g1789520 agaZ 0.3096
aldehyde DHase EC1.2.1.3 (C) g1787558 aldH 0.2994
L-arabinose isomerase EC5.3.1.4 (C) g1786248 araA 1.1773
l-ribulokinase EC2.7.1.16 (C) g1786249 araB 0.2142
L-ribulose-P 4-epimerase EC5.1.3.4 (C) g1786247 araD 0.0734
6-phospho-beta-glucosidase EC3.2.1.86 g1789070 ascB 0.2057
phospho-beta-glucosidase EC3.2.1.86 (C) g1790158 bglB -1.414
phospho-beta-glucosidase B EC3.2.1.86 g1788029 celF -0.3231
phospho-beta-D-galactosidase; alpha-subunit g1789457 ebgA 0.4426
"phospho-beta-D-galactosidase, beta-subunit" g1789458 ebgC -0.8228
fucolose-1-P aldolase EC4.1.2.17 (C) g1789164 fucA -0.9194
fucokinase EC2.7.1.51 (C) g1789168 fucK -1.0777
"1,2-propanediol oxidoreductase (lactaldehyde reductase) EC1.1.1.77 (C)" g1789163 fucO -0.1103
UDP-Glc 4-epimerase EC5.1.3.2 (C) g1786974 galE 0.3346
UTP-glucose-1-phosphate uridylyltransferase EC2.7.7.9 g1788355 galF 0.3464
galactokinase EC2.7.1.6 (C) g1786972 galK 0.4991
aldose 1-epimerase (mutarotase) EC5.1.3.3 g1786971 galM 0.3595
Gal-1-P uridylyltransferase EC2.7.7.10 (C) g1786973 galT -0.1294
Glc-P uridylyltransferase EC2.7.7.9 (C) g1787488 galU 0.0031
galactitol-1-phosphate dehydrogenase EC1.1.1.- (C) g1788407 gatD -1.3004
tagatose-bisphosphate aldolase EC4.1.2.- g1788412 gatY -0.905
putative tagatose 6-phosphate kinase EC2.7.1.- g1788411 gatZ -1.039
glycerol kinase EC2.7.1.30 (C) g1790361 glpK 0.9521
glycerophosphoryl diester phosphodiesterase g1788572 glpQ -0.3809
probable 6-phospho-beta-glucosidase EC3.2.1.86 g1790115 glvG 0.2168
gluconate kinase EC2.7.1.12 g1790719 gntV -2.2986
L-fucose isomerase EC5.3.1. (C)- g1789167 fucI 0.4059
2-keto-3-deoxy-D-gluconate kinase EC2.7.1.45 (C) g1789945 kdgK 0.3332
2-keto-3-deoxygluconate oxydoreductase EC1.1.1.125 g1789208 kduD -0.0699
thiogalactoside acetyltransferase EC2.3.1.18 (C) g1786537 lacA -1.7811
beta-galactosidase (C) g1786539 lacZ -0.2034
cryptic l-xylulose kinase (l-xylulokinase) EC2.7.1.53 g1790005 lyxK 0.0411
mannose-6-phosphate isomerase EC5.3.1.8 g1787899 manA 0.2115
maltodextrin phosphorylase EC2.4.1.1 (C) g1789822 malP 0.5123
4-alpha-glucanotransferase EC2.4.1.25 (C) g1789821 malQ -0.2547
alpha-amylase EC3.2.1.1 g1789995 malS -0.8737
mal inducer biosyn blocker EC2.6.1.- (C) g1787909 malY -0.5285
maltodextrin glucosidase EC3.2.1.20 g1786604 malZ -0.5675
alpha-galactosidase EC3.2.1.22 g1790560 melA -0.2116
mannitol-1-phosphate dehydrogenase EC1.1.1.17 (C) g1790028 mtlD 0.7469
N-acetylneuraminate lyase EC4.1.3.3 g1789620 nanA 0.2353
ribokinase (C) g1790193 rbsK -0.7441
L-rhamnose isomerase EC5.3.1.14 (C) g1790337 rhaA 0.0776
rhamnulose kinase (C) g1790338 rhaB -0.6631
rhamnulose-1-phosphate aldolase EC4.1.2.19 (C) g1790336 rhaD -0.1506
glucitol-6-phosphate dehydrogenase EC1.1.1.140 g1789057 srlD 0.4612
periplasmic trehalase g1787447 treA -0.7986
probable cytoplasmic trehalase (C) g1789936 treF 0.1666
trehalose-6-phosphate hydrolase EC3.2.1.93 (C) g1790687 treC -0.6624
beta-D-glucuronidase EC3.2.1.31 (C) g1787903 uidA 0.1935
5'-nucleotidease=UDP-sugar hydrolase precursor EC3.6.1.45 g1786687 ushA 0.0087
altronate oxidoreductase EC1.1.1.58 (C) g1787800 uxaB 1.0154
D-mannonate hydrolase EC4.2.1.8 (C) g1790778 uxuA 1.9521
D-mannonate oxidoreductase EC1.1.1.57 (C) g1790779 uxuB 1.3956
xylosse isomerase EC5.3.1.5 (C) g1789988 xylA 0.3465
xylulose kinase EC2.7.1.17 (C) g1789987 xylB -0.99
(pentoses in nucleosides and deoxynucleosides)
xanthosine phosphorylase EC2.4.2 (C)- g1788746 xapA -0.2383
phosphopentomutase EC2.7.5.6/EC5.4.2.7 (C)- g1790843 deoB 2.2282
deoxyribose aldolase EC4.1.2.4 (C) g1790841 deoC 2.0214
(fatty acid degradation: FFF)
beta sub of the fatty acid-oxidizing multi enzyme complex EC2.3.1.16 (C) g1790280 fadA -1.6357
alpha sub of the fatty acid-oxidizingmultienzymecomplex (C) g1790281 fadB 0.78
long chain acyl-CoA synthetase EC6.2.1.3 (C) g1788107 fadD 0.0442
6.6 Amino acids and amines
L-asparaginase II EC3.5.1.1 g1789327 ansB 1.6106
"aspartase EC4.3.1.1 (TCA, Anaerobic)" g1790581 aspA 1.679
lysine decarboxylase EC4.1.1.18 g1790573 cadA 1.7141
carbamoyl-phosphate synthase small chain EC6.3.5.5 g1786215 carA 0.3059
carbamoyl-phosphate synthase large chain EC6.3.5.5 g1786216 carB 1.8038
succinate-semialdehyde dehydrogenase EC1.2.1.16 g1789015 gabD 0.3182
glutamate decarboxylase alpha EC4.1.1.15 g1789934 gadA 1.0591
glutamate decarboxylase-beta EC4.1.1.15 g1787769 gadB 1.1099
glycine cleavage system H protein g1789271 gcvH 1.5563
glycine dehydrogenase (decarboxylating) EC 1.4.4.2 g1789269 gcvP 0.9896
aminomethyltransferase EC2.1.2.10 g1789272 gcvT 0.5238
delta-1-pyrroline- 5-carboxylate dehydrogenase EC1.5.99.8 g1787250 putA 0.2148
L-Ser deaminase EC4.2.1.13 g1788116 sdaA 0.6766
7.Fatty acid and phospholipid metabolism
2-acylglycerophosphoethanolamine acyl transferase/acyl carrier protein synthetase g1789201 aas -0.5214
Ac-CoA carboxylase EC6.4.1.2 g1786382 accA 1.0046
biotin carboxyl carrier prt EC6.4.1.2 g1789653 accB 1.9984
biotin carboxylase EC6.3.4.14 g1789654 accC 1.3911
acetyl-CoA carboxylase beta subunit EC6.4.1.2 g1788655 accD 0.9315
acyl carrier protein phosphodiesterase g1787680 acpD 0.8721
acyl carrier prt g1787336 acpP 1.5906
g1788916 acpS -1.1522
CDP-diglyceride hydrolase EC3.6.1.26 g1790352 cdh -1.371
CDP-diglyceride Sase EC2.7.7.41 g1786372 cdsA -0.7052
cyclopropane-fatty-acyl-phospholipid synthase EC2.1.1.79 g1787951 cfa -0.5548
cardiolipin synthetase EC2.7.8.- g1787502 cls -1.1035
diacylglycerol kinase EC2.7.1.107 g1790475 dgkA -0.5193
D-3-hydroxydecanoyl-(acyl carrier-protein) EC 4.2.1.60 g1787187 fabA 1.6101
b-ketoacyl-ACP Sase I EC2.3.1.41 g1788663 fabB 2.1543
malonyl CoA acyl carrier prt transacylase EC2.3.1.39 g1787334 fabD 0.6859
3-oxoacyl-[acyl-carrier-protein] synthase II EC2.3.1.41 g1787337 fabF 0.7815
3-ketoacyl-acyl carrier prt RDase EC1.1.1.100 g1787335 fabG 0.3145
b-ketoacyl-acyl carrier prt Sase III EC2.3.1.41 g1787333 fabH 0.2246
enoyl-[acyl-carrier-protein] reductase (NADH) EC1.3.1.9 g1787545 fabI 1.7521
(3R)-hydroxymyristol acyl carrier prt dehydrase g1786377 fabZ 0.424
fatty acid metabolism prt = fatty acid--fatty acyl responsive DNA-binding protein g1787436 fadR -0.4254
glycerol dehydrogenase EC1.1.1.6 g1790381 gldA 0.7864
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase EC2.3.1.- g1786376 lpxD -0.081
phosphatidylglycerophosphate phosphatase B EC3.1.3.27 g1787534 pgpB -1.783
phosphatidylglycerophosphate Sase EC2.7.8.5 g1788220 pgsA -0.5361
detergent-resistant phospholipase A EC3.1.1.32 g1790255 pldA 0.1314
glycerol-3-P acyltransferase EC2.3.1.15 g1790474 plsB 0.3008
1-acyl-glycerol-3-P acyltransferase EC2.3.1.51 g1789395 plsC 0.0016
probably fatty acid or phospholipid synthesis g1787331 plsX -1.8019
phosphatidylserine DCase proenzyme EC4.1.1.65 g1790604 psd 0.6537
acyl-coA thioesterase I EC3.1.2 g1786702 tesA -0.7689
acyl-CoA thioesterase II EC3.1.2.- g1786657 tesB -0.2508
USG-1 prt g1788658 usg 0.7346
"8.Purines, pyrimidines, nucleotides, and nucleotides"
8.1 2'-Deoxyribonucleotide metabolism (deoxyribonucleotide metabolism)
deoxycytidine triphosphate deaminase EC3.5.4.13 g1788379 dcd 0.7155
deoxyuridinetriphosphatase EC3.6.1.23 g1790071 dut 0.6423
ribonucleoside diphosphate RDase 1 a chain EC1.17.4.1 g1788566 nrdA 1.7266
ribonucleoside diphosphate RDase b2 sub EC1.17.4.1 g1788567 nrdB 1.2272
anaerobic ribonucleoside-triphosphate RDase EC1.17.4.2 g1790686 nrdD 1.1625
ribonucleoside-diphosphate reductase 2 alpha EC1.17.4.1 g1789030 nrdE -0.3675
ribonucleoside-diphosphate reductase 2 beta EC1.17.4.1 g1789031 nrdF -0.3663
thioredoxin RDase EC1.6.4.5 g1787114 trxB 0.4554
thymidylate Sase EC2.1.1.45 g1789191 thyA 0.716
8.2 Purine ribonucleotide biosynthesis
adenylate kinase EC2.7.4.3 (de nova) g1786680 adk 2.2402
GMP reductase EC1.6.6.8 g1786293 guaC 0.6066
5'-guanylate kinase (de nova) g1790080 gmk -0.5364
adenylosuccinate Sase EC6.3.4.4 (de nova) g1790620 purA 2.2316
adenylosuccinate lyase EC4.3.2.2 (de nova) g1787376 purB 1.202
phosphoribosylamine-Gly ligase EC6.3.4.13 (de nova) g1790438 purD 0.8526
phosphoribosylaminoimidazole carboxylase catalytic sub (de nova) g1786734 purE 0.9201
amidoPRTase EC2.4.2.14 (de nova) g1788651 purF 0.693
EC2.1.2.3/EC3.5.4.10 (de nova) g1790439 purH 1.2295
5'-phosphoribosyl-5-amino-4-imidazole carboxylase II EC4.1.1.21 g1786733 purK 0.222
phosphoribosylglycinamide formyltransferase 2 EC2.1.2.- g1788155 purT -0.6367
formyltetrahydrofolate hydrolase EC3.5.1.10 g1787483 purU -0.2341
phosphoribosylpyrophosphate Sase EC2.7.6.1 g1787458 prsA 1.7213
(Purine salvage)
adenosine deaminase EC3.5.4.4 (C) g1787910 add -0.2476
AMP nucleosidase EC3.2.2.4 g1788293 amn -1.1523
adenine PRTase EC2.4.2.7 g1786675 apt 1.4054
purine-nucleoside phosphorylase EC2.4.2.1 (C)- g1790844 deoD 2.072
xanthine-guanine phosphoribosyltransferase EC2.4.2.22 g1786433 gpt 1.2523
hypoxanthine phosphoribosyltransferase EC2.4.2.8 g1786317 hpt 1.4894
8.3 Pyrimidine ribonucleotide biosynthesis
aspartate carbomoyltransferase catalytic subunit EC2.1.3.2 (de nova) g1790693 pyrB -1.9161
dihydroorotase EC3.5.2.3 (de nova) g1787301 pyrC -0.2031
dihydroorotate DHase EC1.3.3.1 (de nova) g1787177 pyrD -0.7513
orotate PRTase (de nova) g1790073 pyrE 0.0163
orotidine-5'-monophosphate DCase EC4.1.1.23 (de nova) g1787537 pyrF -0.5971
CTP Sase EC6.3.4.2 (de nova) g1789142 pyrG 1.0993
uridine 5'-monophosphate kinase EC2.7.4. (de nova)- g1786367 pyrH 1.1536
aspartate carbomoyltransferase regulatory EC2.1.3.2 (de nova) g1790692 pyrI -0.3149
(Pyrimidine salvage)
cytidine deaminase EC3.5.4.5 (C) g1788465 cdd -0.0071
cytosine deaminase EC3.5.4.1 g1786531 codA -0.0826
thymidine phosphorylase EC2.4.2.4 (C)- g1790842 deoA 1.1475
thymidine kinase EC2.7.1.21 g1787490 tdk -1.7246
uridine phosphorylase EC2.4.2.3 (C) g1790265 udp 1.6736
8.4 Nucleotide and nucleoside interconversions
dGTP triphosphohydrolase EC3.1.5.1 g1786355 dgt -1.1039
uridine kinase EC2.7.1.48 g1788380 udk -0.2496
probable adenine deaminase EC3.5.4.2 g1790098 yicP -0.6372
(Others)
adenosine tetraphosphatase=bis(5'-nucleosyl)-tetraphosphatase EC3.6.1.41 g1786234 apaH 0.1297
cytidylate kinase EC2.7.4.14 g1787139 cmk -1.0005
"2',3'-cyclic nucleotide 2'-phosphodiesterase EC3.1.4.16" g1790658 cpdB -0.2297
inosine-guanosine kinase EC2.7.1.73 g1786684 gsk 0.423
putative ATPase g1788431 mrp 0.06
9.Regulatory functions
ADA regulatory protein EC2.1.1.63 g1788542 ada -0.6692
potential acrAB operon repressor g1786669 acrR -1.4978
arsenical resistance operon arsefg repressor g1789916 arsR -0.676
sensor protein EC2.7.3.- g1788549 atoS -1.0596
putative aga operon transcriptional repressor g1789519 agaR -0.2918
putative regulatory protein g1790557 adiY -1.5981
positive regulator of int transcription g1788977 alpA -2.7725
arabinose operon regulatory protein g1786251 araC -0.9003
aerobic respiration control prt g1790863 arcA 1.103
aerobic respiration control sensor prt EC2.7.3.- g1789603 arcB 0.0006
Arg repressor prt g1789633 argR -0.6109
asc operon repressor protein g1789068 ascG -0.8422
regulatory prt g1790182 asnC 0.1975
acetoacetate metabolism regulatory protein g1788550 atoC -1.0002
transcriptional regulatory protein g1788394 baeR -0.0127
sensor protein BaeS EC2.7.3.- g1788393 baeS -0.4794
bacterial adaptive response EC2.7.3.- g1789149 barA -0.739
transcriptional regulatory prt g1790552 basR -0.7351
sensor prt for basR EC2.7.3.- g1790551 basS -0.7847
regulatory protein g1786505 betI -0.3053
positive regulatory protein; cryptic beta-glucoside bgl operon antiterminator g1790160 bglG -1.8498
putative murein gene regulator g1786638 bolA -1.0193
cation transport regulator g1787469 chaB 0.0291
transcriptional activator cadc g1790576 cadC -1.3799
cel operon repressor g1788030 celD -1.4353
curlin genes transcriptional activator g1786435 crl 0.8584
chemosensory transducer EC2.7.3.- g1790346 cpxA 0.3193
transcriptional regulatory protein cpxr g1790347 cpxR -1.3605
catabolic regulation; transcriptional regulatory protein g1790860 creB -1.1628
positive regulatory gene for pho regulon EC2.7.3.-; sensor protein crec g1790861 creC -0.9954
transcriptional regulator g1786838 criR -1.218
necessary for transcription of the csgBA operon g1787277 csgD -1.1636
adenylate cyclase g1790238 cyaA 0.1787
cys regulon transcription activator g1787530 cysB -0.8591
regulation of deo operon; transcriptional repressor g1790369 cytR -0.2952
cyn operon transcriptional activator g1786533 cynR -1.6826
cyclic AMP receptor protein g1789756 crp 1.1717
carbon storage regulator g1789047 csrA 1.167
repressor protein of division inhibition gene dicB g1787853 dicA -1.8568
repressor protein of division inhibition gene dicB g1787852 dicC -1.7657
deoxyribose operon repressor g1787063 deoR -0.7324
regulatory protein g1786405 dniR -0.3541
d-serine deaminase activator g1788706 dsdC -1.1636
ebg repressor g1789456 ebgR -0.3634
potential acref/envcd operon repressor g1789664 envR -1.918
osmolarity sensor EC2.7.3.- g1789808 envZ -0.121
putative sensor protein EC2.7.3.- g1788713 evgS -1.746
putative positive transcription regulator g1788712 evgA -2.1016
exu regulon regulator g1789480 exuR 0.1667
fatty acyl responsive regulator (p30 protein) g1786950 farR -1.0537
probable RNA polymerase sigma factor feci g1790746 fecI -0.5765
transcriptional activator of the formate hydrogen lyasesystem g1789087 fhlA -0.2296
regulatory gene for expression of fimA;recombinase involved in phase variation g1790767 fimB -1.5463
regulatory gene for expression of fimA;recombinase involved in phase variation g1790768 fimE -1.4956
negative regulator of flagellin synthesis (anti-sigmafactor) g1787311 flgM -0.3783
flagellar transcriptional activator g1788201 flhC -0.6406
flagellar transcriptional activator g1788202 flhD -0.7382
RNA polymerase sigma transcription factor for flagellar operon g1788231 fliA -0.5181
putative frv operon regulatory protein g1790331 frvR -1.0468
fumarate (and nitrate) reduction regulatory prt g1787595 fnr 0.5446
fructose repressor g1786268 fruR -0.2406
L-fucose operon activator g1789170 fucR -1.1204
ferric uptake regulation prt g1786899 fur 0.0351
repressor of galETK operon g1789202 galR -0.2112
galactose operon repressor g1788474 galS -0.4241
repressor of the gat operon g1788406 gatR -1.7053
Gly cleavage system transcriptional activator g1789173 gcvA -1.1947
glc operon transcriptional activator g1789353 glcC -0.6247
uridylyl Tase EC2.7.7.59 g1786363 glnD -0.6983
negative regulation of glnA g1790299 glnG -0.2252
glutamine synthetase activity regulation; nitrogen regulatory protein P-II g1786655 glnK 0.3256
negative regulation of glnA EC2.7.3.- g1790300 glnL -0.511
egative regulatory protein of glp regulon g1789830 glpG -0.4713
glycerol-3-P regulon repressor g1789829 glpR 0.0363
regulatory protein g1789608 gltF -0.8893
gtnUKR operon regulator g1789846 gntR -0.1533
glucuronide repressor g1787904 gusR -0.8713
glucitol operon activator g1789058 gutM -0.7021
GTP-binding protein hflx g1790615 hflX 0.0814
repressor of the hip operon g1787786 hipB -1.6312
formate hydrogenlyase regulatory protein g1789080 hycA -0.2187
hydrogenase activity g1790436 hydH -1.0699
transcriptional regulatory protein g1790437 hydG -0.3337
lacZ expression regulator g1789410 icc 0.0172
regulatory gene for aceBAK operon g1790449 iclR -0.9154
transcriptional activator prt g1790208 ilvY -0.5487
sensor protein KdpD EC2.7.3.- g1786912 kdpD -0.7647
lactose operon repressor g1786540 lacI -0.5434
probable activator protein in leuABCD operon g1786264 leuO -1.3879
LexA repressor g1790476 lexA -0.056
NADH dehydrogenase operon transcriptional regulator g1788626 lrhA -0.4916
Leu responsive regulatory prt g1787116 lrp -0.5571
positive regulatory gene g1789204 lysR -0.9506
regulatory gene g1786976 modE -0.519
regulatory gene for mar g1787812 marB -2.183
repressor protein g1787906 malI -1.3512
positive regulatory gene for mal regulon g1789824 malT -0.107
regulatory gene g1790559 melR -0.5423
metF aporepressor g1790373 metJ 0.2979
trans-activator of metE and metH g1790262 metR -0.9622
molybdate metabolism regulator g1788433 molR -1.7178
multicopy suppressor of htrB g1788161 msbB -0.6971
acidic protein MsyB; multicopy suppressor of SecY g1787289 msyB -1.9175
mannitol operon repressor g1790029 mtlR -0.2041
nitrogen assimilation control protein g1788297 nac -1.8736
nadAB transcriptional regulator g1790851 nadR -0.1099
"nitrate, nitrite response regulator prt" g1788521 narP -0.6825
nitrate/nitrite response regulator protein g1787473 narL -0.3693
nitrate/nitrite sensor protein EC2.7.3.- g1787474 narX -0.7427
transcriptional activator protein nhaR g1786202 nhaR -1.1289
anaerobic ribonucleoside-triphosphate reductase activating pr g1790685 nrdG -0.1882
regulatory protein RecX g1789050 oraA -0.806
hydrogen peroxide-inducible activator g1790399 oxyR 0.1631
positive regulatory gene for ompC and ompF g1789809 ompR 0.7909
pyruvate dehydrogenase complex repressor g1786303 pdhR -0.2104
pyruvate formate-lyase 1 activating enzyme EC1.97.1.4 g1787130 pflA 0.5301
transcriptional regulatory protein g1787375 phoP -0.6883
sensor protein EC2.7.3.- g1787374 phoQ -1.0017
phosphate regulon sensor prt EC2.7.3.- g1786600 phoR -0.4806
phosphate regulon transcriptional regulatory prt g1786599 phoB -0.7802
purine nucleotide synthesis repressor prt g1787947 purR 0.4449
rbs repressor g1790194 rbsR -0.6959
regulator of capsule synthesis B component g1788546 rcsB 0.0539
sensor protein RcsC EC2.7.3.- g1788548 rcsC -0.8418
stimulates colanic acid capsule synthesis g1786394 rcsF -0.877
l-rhamnose operon transcriptional activator rhaR g1790340 rhaR -1.065
l-rhamnose operon regulatory protein rha g1790339 rhaS -1.2275
ATP:GTP 3'-pyrophosphotransferase EC2.7.6.5 g1789147 relA 0.316
"transcriptional activator of lipopolysacharide, sex factor and haemolysin genes" g1790276 rfaH -0.7232
regulator of nucleoside diphosphate kinase g1786827 rnk -0.112
sigma-E factor negative regulatory protein g1788925 rseA -0.4819
sigma-E factor regulatory protein g1788924 rseB -0.9885
sigma-E factor regulatory protein g1788923 rseC -1.0121
suppresses ftsI mutation g1789394 sufI -0.3052
regulatory protein g1788224 sdiA -1.2516
ftsH suppressor protein g1788946 sfhB 0.0824
htrA suppressor protein g1789517 sohA -0.3241
regulation of superoxide response regulon g1790498 soxR -1.0958
regulation of superoxide response regulon g1790497 soxS -0.6303
glucitol operon repressor g1789059 srlR -0.3896
penta-P guanosine-3'-pyrophosphohydrolase g1790082 spoT 0.2427
stringent starvation prt A g1789624 sspA 1.3023
stringent starvation prt B g1789623 sspB -0.0794
maltose regulatory prt sfs1=sugar fermentation stimulation protein g1786340 sfsA -1.3187
tdcABC operon transcriptional activator g1789506 tdcA -1.5098
tdcABC operon transcriptional activator g1789507 tdcR -2.273
torCAD operon transcriptional regulatory protein g1787229 torR -0.4632
"sensor protein TorS, histidine protein kinase EC2.7.3.-" g1787227 torS -0.5623
regulatory gene for treBC operon g1790689 treR -0.2309
Trp repressor g1790854 trpR -1.0563
transcriptional regulatory prt g1787583 tyrR -0.7819
transcriptional regulatory protein g1790102 uhpA -0.3205
regulatory protein g1790100 uhpC -1.2827
uxu operon regulator g1790780 uxuR -0.1094
xylose operon regulatory prt g1789993 xylR -1.4074
ile repressor protein g1790669 yjfA -0.867
10.Replication
10.1 Degradation of DNA
endonuclease I EC3.1.21.1 g1789314 endA -0.0442
potential 5'-3' exonuclease EC3.1.11.- g1789162 exo -1.2821
endonuclease IV EC3.1.21.2 g1788483 nfo -0.1478
"endonuclease VIII, DNA N-glycosylase with an AP lyase activity" g1786932 nei -0.8983
endonuclease III EC4.2.99.18 g1787920 nth -0.3583
endonuclease R EC3.1.21.3 g1790809 hsdR 0.292
excinuclease ABC sub A g1790493 uvrA 0.3411
excinuclease ABC sub B g1786996 uvrB 0.2021
excinuclease ABC sub C g1788221 uvrC -0.3151
exodeoxyribonuclease V EC3.1.11.5 g1789183 recB -0.2991
exodeoxyribonuclease V EC3.1.11.5 g1789186 recC -0.1757
exodeoxyribonuclease V EC3.1.11.5 g1789182 recD -0.7057
single-stranded DNA-specific exonuclease EC3.1.-.- g1789259 recJ -0.3414
exodeoxyribonuclease VIII g1787612 recE -0.466
exodeoxyribonuclease I EC3.1.11.1 g1788321 sbcB -0.6366
exonuclease g1786597 sbcC -0.6295
exonuclease g1786598 sbcD -0.6539
exonuclease III EC3.1.11.2 g1788046 xthA 0.4705
"10.2 DNA replication, restriction, modification, recombination, and repair"
DNA-3-methyladenine glycosidase II EC3.2.2.21 g1788383 alkA -1.0915
DNA adenine methylase EC2.1.1.72 g1789789 dam -0.6325
ATP-dependent RNA helicase g1787605 dbpA -1.087
probable ATP-dependent helicase g1787018 dinG -0.4293
DNA-damage-inducible protein d g1790076 dinD -1.5948
dosage-dependent dnaK suppressor prt g1786338 dksA 0.7655
chromosomal replication initiator g1790137 dnaA -0.7343
replicative DNA helicase EC3.6.1.- g1790486 dnaB 0.31
DNA biosynthesis; initiation and chain elongation g1790823 dnaC -0.1675
DNA polymerase III a sub EC2.7.7.7 g1786381 dnaE 0.4812
DNA primasse EC2.7.7.- g1789447 dnaG -0.9552
DNA polymerase III b sub EC2.7.7.7 g1790136 dnaN 0.5303
DNA polymerase III e sub EC2.7.7.7 g1786409 dnaQ -1.4457
DNA biosynthesis; primasomal protein i g1790824 dnaT 0.0697
DNA polymerase III sub g and tau EC2.7.7.7 g1786676 dnaX -0.2409
Hin recombinational enhancer BP g1789661 fis 1.4376
glucose-inhibited division prt g1790180 gidA 0.7331
glucose-inhibited division prt g1790179 gidB -0.3567
"DNA gyrase, sub A EC5.99.1.3" g1788562 gyrA 1.5155
"DNA gyrase, sub B EC5.99.1.3" g1790134 gyrB 1.8763
helicase IV (75 kD helicase) EC3.6.1.- g1787196 helD -0.6429
integration host factor a sub g1788005 himA -0.8965
integration host factor b sub(IHF-b) g1787141 himD -0.7451
DNA polymerase III d sub EC2.7.7.7 g1786859 holA -1.1417
DNA polymerase III d' sub EC2.7.7.7 g1787341 holB -0.6963
DNA polymerase III c sub EC2.7.7.7 g1790709 holC -0.2774
DNA polymerase III psi sub EC2.7.7.7 g1790831 holD -0.6844
ATP-dependent helicase g1787681 hrpA 0.1475
ATP-dependent helicase g1786342 hrpB -0.7904
DNA methylase M; host modification EC2.1.1.72 g1790808 hsdM 0.9378
type I restriction enzyme ecoki specificity g1790807 hsdS -1.7552
restriction alleviation and modification enhancement protein g1787610 lar -2.7971
probable ATP-dependent helicase EC3.6.1.- g1787942 lhr -1.0204
DNA ligase EC6.5.1.2 g1788750 lig 0.2896
5-methylcytosine-specific restriction enzyme A EC3.1.21.- g1787406 mcrA -2.4152
restriction of DNA at 5-methylcytosine residues EC3.1.21.- g1790805 mcrB -1.6079
sequences restricted g1790804 mcrC -2.0294
modulation of initiation at oriC g1790181 mioC -0.0249
restriction of methylated adenine g1790811 mrr -0.629
mutator mutT EC3.6.1.- g1786288 mutT -0.8311
transcription-repair coupling factor g1787357 mfd -0.0966
formamidopyrimidine-DNA glycosylase EC3.2.2.- g1790066 mutM -0.9538
A/G-specific adenine glycosylase EC3.2.2.- g1789331 mutY -1.1279
DNA mismatch repair prt g1789196 mutH -1.1114
DNA mismatch repair prt g1790612 mutL -0.3926
DNA mismatch repair prt g1789089 mutS 0.2646
O6-methylguanine-DNA-alkyltransferase EC2.1.1.63 g1787596 ogt -1.502
topoisomerase IV sub A EC5.99.1.- g1789396 parC 0.609
topoisomerase IV sub B EC5.99.1.- g1789408 parE 0.4245
deoxyribodipyrimidine photolyase EC4.1.99.3 g1786926 phrB -0.9703
DNA-invertase g1787404 pin -1.4715
DNA polymerase I EC2.7.7.7 g1790294 polA 0.3156
DNA polymerase II EC2.7.7.7 g1786246 polB -0.0675
primosomal prt replication factor g1790370 priA -0.1184
primosomal replication protein n g1790645 priB -1.2145
primosomal replication protein N g1786673 priC -0.4956
DNA recombinase EC3.6.1.- g1790084 recG -0.1319
DNA helicase EC3.6.1.- g1790256 recQ -0.009
"DNA, ATP-BP" g1790135 recF -0.8788
recombinase g1789051 recA 2.3823
recombination and DNA repair g1788969 recN -0.3083
binds ssDNA and promotes renaturation g1787611 recT -0.6035
recombination protein g1786678 recR 0.4379
rep helicase EC3.6.1.- g1790212 rep 0.1025
putative ATP-dependent RNA helicase g1787016 rhlE 0.8293
Holliday junction DNA helicase g1788168 ruvA -0.7249
Holliday junction DNA helicase g1788167 ruvB -0.2393
crossover junction endodeoxyribonuclease g1788170 ruvC -0.032
negative modulator of initiation of replication g1786903 seqA -0.4483
single-stranded DNA BP g1790494 ssb 1.8515
topoisomerase III EC5.99.1.2 g1788061 topB -0.3011
DNA 3-methyladenine glycosidase I EC3.2.2.20 g1789971 tag -0.9653
DNA topoisomerase I EC5.99.1.2 g1787529 topA 0.6066
DNA replication terminus site-binding protein g1787895 tus -0.8181
DNA helicase II EC3.6.1.- g1790246 uvrD 0.2354
integrase-recombinase prt g1790244 xerC 0.0167
integrase-recombinase prt g1789261 xerD -0.7479
exodeoxyribonuclease small subunit EC3.1.11.6 g1786624 xseB 0.5297
11 Transcription
11.1 Degradation of RNA
ribonuclease I precursor EC3.1.27.6 g1786828 rna -0.6563
exoribonuclease II EC3.1.13.1 g1787542 rnb 0.3099
ribonuclease D EC3.1.26.3 g1788105 rnd -0.0776
ribonuclease E g1787325 rne 0.8602
RNase P EC3.1.26.5 g1790139 rnpA -1.3889
ribonuclease H EC3.1.26.4 g1786408 rnhA -0.8534
ribonuclease HII EC3.1.26.4 g1786380 rnhB 0.0419
RNase T EC3.1.13.- g1787941 rnt 0.377
ribonuclease PH g1790074 rph 0.6852
"11.2 RNA synthesis, modification, and DNA transcription"
ATP-dependent helicase g1786245 hepA 1.2176
ATP-dependent RNA helicase g1790214 rhlB 0.2489
DNA-directed RNA polymerase a chain EC2.7.7.6 g1789690 rpoA 0.8427
DNA-directed RNA polymerase b chain EC2.7.7.6 g1790419 rpoB 2.1308
DNA-directed RNA polymerase b' chain EC2.7.7.6 g1790420 rpoC 2.6183
RNA polymerase sigma-70 factor g1789448 rpoD 1.9194
RNA polymerase sigma-32 factor EC2.7.7.6 g1789871 rpoH 1.4561
RNA polymerase sigma-54 factor (sigma-N) g1789594 rpoN -0.0914
RNA polymerase sigma subunit RpoS (sigma-38) g1789098 rpoS -0.0741
RNA polymerase omega sub EC2.7.7.6 g1790081 rpoZ 1.1762
transcription terminator g1789560 nusA 1.4698
N utilization substance prt B g1786618 nusB 0.5914
transcription antitermination prt g1790414 nusG 1.4591
poly(A) polymerase EC2.7.7.19 g1786336 pcnB 0.8346
polynucleotide phosphorylase EC2.7.7.8 g1789555 pnp 2.2702
transcription elongation factor g1789810 greB 0.244
13.Translation
13.1 Amino acyl tRNA synthetases
Ala-tRNA Sase EC6.1.1.7 g1789048 alaS 1.0183
Arg-tRNA Sase EC6.1.1.19 g1788184 argS 1.2454
Asn-tRNA Sase EC6.1.1.22 g1787161 asnS 1.1332
Asp-tRNA Sase EC6.1.1.12 g1788173 aspS 1.9173
Cys-tRNA Sase EC6.1.1.16 g1786737 cysS 0.9575
Gln-tRNA Sase EC6.1.1.18 g1786895 glnS 1.6498
Gly-tRNA Sase a chain EC6.1.1.14 g1789983 glyQ 1.5856
Gly-tRNA Sase b chain EC6.1.1.14 g1789982 glyS 1.8776
Ile-tRNA Sase EC6.1.1.5 g1786209 ileS 1.5279
Leu-tRNA Sase EC6.1.1.4 g1786861 leuS 1.8061
Lys-tRNA Sase EC6.1.1.6 g1789256 lysS 1.9273
lysyl-tRNA synthetase EC6.1.1.6 g1790571 lysU 0.2939
lysyl-tRNA synthetase analog EC6.1.1.6 g1790599 yjeA -0.5732
Met-tRNA Sase EC6.1.1.10 g1788432 metG 1.3537
Phe-tRNA Sase a sub EC6.1.1.20 g1788007 pheS 1.2934
Phe-tRNA Sase b sub EC6.1.1.20 g1788006 pheT 1.4544
Pro-tRNA Sase EC6.1.1.15 g1786392 proS 1.7959
Ser-tRNA Sase EC6.1.1.11 g1787120 serS 1.2485
Thr-tRNA Sase EC6.1.1.3 g1788013 thrS 0.7781
Trp-tRNA Sases EC6.1.1.2 g1789786 trpS 1.0241
Tyr-tRNA Sase EC6.1.1.1 g1787925 tyrS 1.196
Val-tRNA Sase EC6.1.1.9 g1790708 valS 2.018
13.2 tRNA modification
tRNA nucleotidyltransferase EC2.7.7.25 g1789436 cca -0.3512
Met-tRNA formyltransferase EC2.1.2.9 g1789683 fmt -0.3751
tRNA delta-2-isopentenylpyrophosphate (IPP) transferase EC2.5.1.- g1790613 miaA -1.248
peptidyl-tRNA hydrolase EC3.1.1.29 g1787455 pth -1.3006
S-adenosylmethionine:tRNA ribosyltransferase- isomerase g1786606 queA -0.2771
? selenium metabolism prt g1788062 selD 0.2253
tRNA-guanine transglycosylase EC2.4.2.29 g1786607 tgt 0.2778
tRNA (U-5-)-MTase EC2.1.1.35 g1790403 trmA -0.0428
tRNA(guanine-7)methyltransferase EC2.1.1.31 g1788959 trmD -0.8654
pseudouridylate synthase I EC4.2.1.70 g1788657 truA -0.2932
trna pseudouridine 55 synthase (psi55 synthase) g1789557 truB 0.4287
"13.3 Degradation of proteins, peptides, and glycopeptides"
ATP-dependent Clp protease ATP-binding subunit g1787109 clpA 0.4754
ATP-dependent clp protease proteolytic subunit EC3.4.21.92 g1786641 clpP 0.0233
ATP-dependent protease ATPase sub g1786642 clpX 1.1301
D-alanine carboxypeptidase EC3.4.16.4 g1786851 dacA 0.7303
dipeptidyl carboxypeptidase II EC3.4.15.5 g1787819 dcp -0.7528
HflC EC3.4.-.- g1790617 hflC 1.691
protease for l cII repressor g1790616 hflK 0.7658
protease EC3.4.21.- g1789629 hhoA -1.0764
protease EC3.4.21.- g1789630 hhoB 0.0635
type 4 prepilin-like protein specific leader peptidase g1789732 hofD -1.5859
periplasmic Ser protease Do EC3.4.21.- g1786356 htrA 1.545
isoaspartyl dipeptidase EC3.4.19.5 g1790784 iadA -0.0108
penicillin-insensitive murein endopeptidase EC3.4.99.- g1788668 mepA -0.5311
lon protease EC3.4.21.53 g1786643 lon 1.2109
protease VII precursor EC3.4.21.87 g1786777 ompT -1.317
aminopeptidase A EC3.4.11.1 g1790710 pepA 0.6297
peptidase D EC3.4.13.3 g1786432 pepD 1.4654
peptidase E g1790452 pepE 0.3499
aminopeptidase N EC3.4.11.2 g1787163 pepN 0.6279
aminopeptidase P EC3.4.11.9 g1789275 pepP 0.3772
Pro dipeptidase EC3.4.13.9 g1790282 pepQ 1.1521
peptidase T EC3.4.11.- g1787372 pepT -0.2552
tail-specific protease EC3.4.21.- g1788134 prc 0.0848
oligopeptidase A g1789913 prlC 1.1393
protease III precursor (pitrilysin) EC3.4.24.55 g1789184 ptr -0.5855
protease II EC3.4.21.83 g1788150 ptrB -0.7961
ATP-dependent protease g1790850 sms -0.0335
protease EC3.4.-.- g1787527 sohB -0.8128
protease IV EC3.4.-.- g1788064 sppA 0.2349
13.4 Nucleoproteins
histone-like protein g1786375 hlpA 1.1172
DNA-BP H-NS g1787489 hns 1.0797
histonelike DNA-binding protein HU-alpha (NS2) g1790433 hupA 2.1613
DNA-binding protein HU-beta g1786644 hupB 1.5097
DNA-binding protein g1789023 stpA 0.3357
protamine-like protein g1787482 tpr -1.6564
13.5 Protein modification and translation factors
leucyl/phenylalanyl-tRNA--protein transferase EC2.3.2.- g1787111 aat -1.444
f-Met deformylase EC3.5.1.27/EC3.5.1.31 g1789682 def -0.5879
elongation factor P g1790590 efp 2.046
ribosome releasing factor g1786368 frr 1.8025
elongation factor G g1789738 fusA 2.673
Glu-ammonia-ligase adenylyltransferase EC2.7.7.42 g1789433 glnE -0.3625
initiation factor IF-1 g1787110 infA 0.1376
initiation factor IF-2 g1789559 infB 1.9864
initiation factor IF-3 g1788012 infC -0.5397
Met aminopeptidase EC3.4.11.18 g1786364 map 0.7528
peptide methionine sulfoxide reductase g1790665 msrA -0.0311
maturation of antibiotic MccB17 g1790682 pmbA 0.1629
peptidyl-prolyl cis-trans isomerase A EC5.2.1.8 g1789763 ppiA 0.6831
peptidyl-prolyl cis-trans isomerase B EC5.2.1.8 g1786736 ppiB 2.389
peptidyl-prolyl cis-trans isomerase C EC5.2.1.8 g1790211 ppiC 0.5795
peptide chain release factor 1 g1787462 prfA 0.2916
peptide chain release factor 2 g1789257 prfB -1.6634
peptide chain release factor 3 g1790835 prfC 1.4242
peptide chain release factor homolog (RF-H) g1786431 prfH -0.3851
ribosome-binding factor a (p15b protein) g1789558 rbfA 1.2615
"rotamase, peptidyl prolyl cis-trans isomerase" g1789748 slyD 2.1601
elongation factor EF-Ts g1786366 tsf 2.5619
elongation factor EF-Tu g1789737 tufA 3.4349
elongation factor EF-Tu g1790412 tufB 3.2913
13.6 Ribosomal proteins
ribosomal prt L1 g1790416 rplA 2.5381
ribosomal prt L2 g1789713 rplB 2.2271
ribosomal prt L3 g1789716 rplC 1.8822
ribosomal prt L4 g1789715 rplD 2.6539
ribosomal prt L5 g1789704 rplE 1.5816
ribosomal prt L6 g1789701 rplF 2.0139
ribosomal prt L7/L12 g1790418 rplL 2.95
ribosomal prt L9 g1790647 rplI 1.9844
ribosomal prt L10 g1790417 rplJ 2.0104
ribosomal prt L11 g1790415 rplK 2.5318
ribosomal prt L13 g1789626 rplM 1.4328
ribosomal prt L14 g1789706 rplN 1.196
ribosomal prt L15 g1789697 rplO 2.6348
ribosomal prt L16 g1789709 rplP 1.8794
ribosomal prt L17 g1789689 rplQ 1.1971
ribosomal prt L18 g1789700 rplR 2.0975
ribosomal prt L19 g1788958 rplS 2.1649
ribosomal prt L20 g1788009 rplT 2.2355
ribosomal prt L21 g1789577 rplU 1.3619
ribosomal prt L22 g1789711 rplV 1.6465
ribosomal prt L23 g1789714 rplW 3.0056
ribosomal prt L24 g1789705 rplX 1.8774
ribosomal prt L25 g1788512 rplY 2.5754
ribosomal prt L27 g1789576 rpmA 2.442
ribosomal prt L28 g1790068 rpmB 2.7271
ribosomal prt L29 g1789708 rpmC 1.2
ribosomal prt L30 g1789698 rpmD 0.9662
ribosomal prt L31 g1790371 rpmE 1.9303
ribosomal prt L32 g1787330 rpmF 1.8388
ribosomal prt L33 g1790067 rpmG 2.5569
ribosomal prt L34 g1790138 rpmH 2.5514
ribosomal prt L35 g1788010 rpmI 2.5834
ribosomal prt L36 g1789695 rpmJ -0.4878
ribosomal prt S1 g1787140 rpsA 2.8912
ribosomal prt S2 g1786365 rpsB 2.7448
ribosomal prt S3 g1789710 rpsC 2.5502
ribosomal prt S4 g1789691 rpsD 1.5334
ribosomal prt S5 g1789699 rpsE 1.7558
ribosomal prt S6 g1790644 rpsF 2.3295
ribosomal prt S7 g1789739 rpsG 1.1594
ribosomal prt S8 g1789702 rpsH 1.5176
ribosomal prt S9 g1789625 rpsI 3.1495
ribosomal prt S10 g1789717 rpsJ 2.0304
ribosomal prt S11 g1789692 rpsK 1.5251
ribosomal prt S12 g1789740 rpsL 2.3884
ribosomal prt S13 g1789693 rpsM 0.5929
ribosomal prt S14 g1789703 rpsN 1.2627
ribosomal prt S15 g1789556 rpsO 1.7888
ribosomal prt S16 g1788961 rpsP 1.3507
ribosomal prt S17 g1789707 rpsQ 2.5478
ribosomal prt S18 g1790646 rpsR 1.9423
ribosomal prt S19 g1789712 rpsS 0.7546
ribosomal prt S20 g1786206 rpsT 2.0557
ribosomal prt S21 g1789446 rpsU 2.7574
ribosomal prt S22 g1787755 rpsV -0.1085
13.7 synthesis and modification
methylation of 50S ribosomal subunit protein L11 g1789657 prmA 0.3793
ribosomal prt S6 modification prt g1787076 rimK -0.1416
ribosomal-protein-serine acetyltransferase EC2.3.1.- g1787697 rimL -1.0747
ribosomal-prt-Ala acetyltransferase EC2.3.1.128 g1790832 rimI -0.8214
acetylates N-terminal alanine of ribosomal proteinS5 EC2.3.1.128 g1787305 rimJ -1.1116
ribosome modulation factor (protein E) g1787186 rmf -1.3859
14.Transport and binding protein
"14.1 Amino acids, peptides and amines"
lysine-arginine-ornithine-binding periplasmic protein g1788649 argT 0.2733
aromatic amino acid transport protein g1786302 aroP 0.8347
Arg-BP g1787088 artI 1.7464
arginine-binding periplasmic protein 2 g1787085 artJ 0.711
Arg permease g1787086 artM 0.0597
Arg transport ATP-BP g1787089 artP 0.7699
Arg permease g1787087 artQ -0.2717
LIV-II transport system=branched chain amino acid transport system II g1786601 brnQ 1.0454
d-serine/d-alanine/glycine transporter g1790653 cycA -0.4309
ammonium transport protein g1790659 cysQ 0.6036
dipeptide transporter g1789966 dppA 1.3962
dipeptide permease g1789965 dppB 0.2043
dipeptide permease g1789964 dppC 0.6704
dipeptide transport ATP-BP g1789963 dppD 0.3053
dipeptide transport ATP-BP g1789962 dppF 0.5365
DsdX permease g1788707 dsdX -1.3738
biopolymer transport prt g1789381 exbB 0.2274
biopolymer transport prt g1789380 exbD -0.3935
GabA permease (4-amino butyrate transport carrier) g1789017 gabP -0.9215
Gln-BP g178703? glnH 1.6322
Gln permease g1787030 glnP 0.9419
glutamine transport ATP-binding protein g1787029 glnQ 1.1193
glutamate/aspartate transport system permease g1786874 gltJ -0.0934
glutamate/aspartate transport system permease g1786873 gltK 0.0725
glutamate/aspartate transport ATP-binding g1786872 gltL 0.9729
Glu permease g1790085 gltS 0.1989
proton Glu symport prt g1790514 gltP 1.007
histidine-binding periplasmic protein g1788648 hisJ 0.1155
histidine transport ATP-binding protein g1788644 hisP -0.431
histidine transport system permease protein g1788646 hisQ -0.1761
high-affinity branched-chain amino acid transport ATP-binding g1789863 livF -0.0267
Leu-specific transport prt g1789864 livG 0.1217
high-affinity branched chain amino acid transport system g1789866 livH 0.7403
leu/ile/val-binding protein precursor g1789870 livJ 1.0674
"leucine-specific binding protein precursor""" g1789867 livK 0.889
high-affinity branched chain amino acid transport system g1789865 livM 0.5817
lysine-specific permease g1788480 lysP 1.4136
oligopeptide-BP g1787495 oppA 0.1907
oligopeptide permease g1787497 oppB -0.6915
oligopeptide permease g1787498 oppC -0.0361
oligopeptide permease ATP-BP g1787499 oppD -0.4458
oligopeptide permease ATP-BP g1787500 oppF -0.2491
phenylalanine-specific permease g1786789 pheP 0.3026
high-affinity transport system for glycine betaine and proline g1789032 proV -1.2335
high-affinity transport system for glycine betaine and proline g1789033 proW -0.2177
glycine betaine-binding periplasmic protein g1789034 proX 0.4922
peptide permease g1787551 sapA -0.5413
peptide permease g1787550 sapB -0.669
peptide permease g1787549 sapC -0.1554
peptide permease ATP-BP g1787548 sapD -0.5633
uptake of the peptide antibiotic microcin B17 g1786575 sbmA 0.2918
Ser transporter g1789160 sdaC 2.2982
low affinity tryptophan permease g1790145 tnaB -0.5248
spermidine-putrescine permease ATP-BP g1787370 potA -0.0744
spermidine-putrescine permease g1787369 potB 0.7129
spermidine-putrescine permease g1787368 potC -0.0869
spermidine-putrescine-BP g1787367 potD 1.0375
putrescine permease=putrescine-ornithine antiporter g1786908 potE 0.3169
putrescine-binding periplasmic protein g1787078 potF 0.1471
putrescine transport system permease protein g1787080 potH -0.3121
putrescine transport system permease protein g1787081 potI -1.2456
active uptake of proline or betaine g1790550 proP 0.1796
threonine-serine permease g1789504 tdcC 1.1473
Tyr-specific transport prt g1788218 tyrP -0.7804
trp repressor binding protein g1787239 wrbA 0.1625
14.2 Anions
putative sulfate transport protein g1788753 cysZ -0.7844
cyanate permease EC4.2.1.1 g1786534 cynT -0.5317
low-affinity phosphate transport g1789907 pitA 0.5208
peripheral membrane prt B g1790162 pstB 1.6946
peripheral membrane prt C g1790164 pstC 1.055
periplasmic phosphate-BP g1790165 pstS 0.7466
phosphate transport system permease protein g1790163 pstA 1.2445
periplasmic sulphate binding protein g1790351 sbp 0.2442
"14.3 Carbohydrates, organic alcohols, and acids"
(PTS)
"PTS system, n-acetylgalactosamine-specific IIb" g1789527 agaB 0.0318
"pts system, n-acetylgalactosamine-specific IIC" g1789528 agaC -0.8765
"pts system, n-acetylgalactosamine-specific IID" g1789529 agaD 0.1493
"pts system, n-acetylgalactosamine-specific IIb component2" g1789521 agaV -0.1323
"pts system, n-acetylgalactosamine-specific IIc component2" g1789522 agaW 0.0432
phosphotransferase enzyme IIABC-Asc g1789069 ascF -0.0969
"pts system, cellobiose-specific IIB component EC2.7.1.69" g1788034 celA -0.4248
phosphoenolpyruvate dependent phosphotransferaseenzymeII-cellobiose g1788032 celB -0.2059
phosphoenolpyruvate dependent phosphotransferase enzymeIII-cellobiose EC2.7.1.69 g1788031 celC -1.3385
"Glc phosphotransferase enzyme III=?pts system, glucose-specific IIA component" g1788757 crr 1.7899
"pts system, fructose-like-1 IIbc component (phosphotransferas)" g1790333 frvB 0.2039
"pts system, fructose-like-2 IIc component (phosphotransferase)" g1790386 frwC 0.6757
"pts system, fructose-like-2 IIb component 1 (phosphotransfera)" g1790387 frwB 0.324
"pts system, fructose-like-2 IIb component 2 (phosphotransfera)" g1790390 frwD -0.4753
"pts system, galactitol-specific IIA component" g1788410 gatA -1.6974
"pts system, galactitol-specific IIB component" g1788409 gatB -1.5558
"pts system, arbutin-like IIb component " g1790116 glvB 0.5038
pts system arbutin-like IIC component g1790117 glvC -0.2751
"pts system, maltose and glucose-specific II ABC component " g1787908 malX 0.0854
"phosphotransferase enzyme II, AB component EC2.7.1.69" g1788120 manX 0.374
"phosphotransferase enzyme II, C component" g1788121 manY 1.7215
"phosphotransferase enzyme II, D component" g1788122 manZ 1.6177
mannitol-specific enzyme II of phosphotransferasesystem g1790027 mtlA 1.7582
phosphocarrier protein Npr (nitrogen related hpr) g1789599 ptsO -0.6167
"PTS system, glucose-specific IIBC component EC2.7.1.69" g1787343 ptsG 1.8355
phosphocarrier protein Hpr g1788755 ptsH 0.9404
phosphoenolpyruvate-protein phosphotransferase EC2.7.3.9 g1788756 ptsI 0.9655
PTS related carbon and organic nitrogen regulation EC2.7.1.69 g1789597 ptsN -0.273
PTS related carbon and organic nitrogen regulation EC2.7.3.9 g1789193 ptsP -0.7328
"PTS system, glucitol/sorbitol-specific IIA EC2.7.1.69" g1789056 srlB -0.5968
phosphotransferase system trehalose permease g1790688 treB -0.3864
(Others)
low affinity L-arabinose transport system EC5.3.1.4 g1789207 araE 0.0168
L-arabinose-binding periplasmic protein g1788211 araF 0.9503
L-arabinose transport ATP-binding protein AraG g1788210 araG -0.4912
l-arabinose transport system permease protein g1788208 araH -0.1017
transport protein g1790159 bglF -0.8958
cryptic mannitol transport EC2.7.1.69 g1789301 cmtA -0.2516
cryptic mannitol transport EC2.7.1.69 g1789302 cmtB -2.3245
uptake of C4-dicarboxylic acids g1789947 dctA 0.8107
Asp transport prt g1790580 dcuA 1.4913
anaerobic c4-dicarboxylate transporter dcub g1790565 dcuB 0.9416
probable formate transporter (formate channel) g1787132 focA -0.0886
fructose permease IIBC component EC2.7.1.69 g1788492 fruA 1.0318
fructose permease IIA/FPR component EC2.7.1.69 g1788494 fruB 0.2513
L-fucose permease g1789166 fucP -0.8876
fucose operon prt g1789169 fucU -1.3791
galactose-proton symport (galactose transporter g1789312 galP 0.6022
gluconate permease g1790776 gntP 0.8255
glycerol-3-phosphatase transporter g1788573 glpT 0.1798
high-affinity gluconate transporter g1789820 gntT 1.5447
alpha-ketoglutarate permease g1788942 kgtP -1.2538
potassium channel homolog g1787503 kch -1.7194
2-keto-3-deoxygluconate transport g1790343 kdgT -0.3743
lactose permease (lactose-proton symport) g1786538 lacY -0.2622
lactam utilization prt=phage lambda receptor protein g1790469 lamB 0.8699
l-lactate permease g1790031 lldP 0.4906
periplasmic maltose-binding protein g1790466 malE 1.5855
maltose transport inner membrane protein g1790465 malF -0.0375
maltose transport inner membrane protein g1790464 malG 0.8419
cytoplasmic membrane protein for maltose uptake g1790467 malK 0.4849
thiomethylgalactoside permease II g1790561 melB -1.1967
methylgalactoside permease ATP-BP g1788472 mglA -0.8111
methylgalactoside-BP g1788473 mglB 1.4467
methylgalactoside permease g1788471 mglC 0.3784
high affinity ribose transport prt g1790190 rbsA -0.1232
periplasmic ribose-BP g1790192 rbsB 0.7415
high affinity ribose transport prt g1790191 rbsC 0.1908
high affinity ribose transport prt g1790189 rbsD -0.4857
rhamnose permease g1790341 rhaT -0.5927
sn-Glycerol-3-phosphate transport system permease protein g1789861 ugpA 0.3125
glycerol-3-phosphate-binding periplasmic protein precursor g1789862 ugpB 0.6594
sn-Glycerol-3-phosphate transport ATP-binding g1789859 ugpC -0.1713
sn-Glycerol-3-phosphate transport system permease protein g1789860 ugpE 0.1196
hexose phosphate transport protein g1790099 uhpT -1.0659
hexose phosphate transport protein; sensor protein EC2.7.3.- g1790101 uhpB -0.4487
glucuronide permease g1787902 uidB -0.3553
xylose-proton symport g1790463 xylE 0.2749
D-xylose transport ATP-BP g1789991 xylG -1.1677
ribose permease g1789992 xylH -0.4663
14.4. Cations
cation transport protein g1787470 chaC -0.6272
magnesium and cobalt transport prt g1790248 corA 0.8549
iron(III) dicitrate transport protein g1790743 fecA 0.4807
citrate-dependent iron transport; periplasmic protein g1790742 fecB 0.0896
iron(III) dicitrate transport system permease g1790741 fecC -0.1918
iron(III) dicitrate permease g1790740 fecD -0.3318
iron(III) dicitrate transport ATP-BP g1790739 fecE -1.2607
nickel-binding periplasmic protein g1789887 nikA 0.3132
ferrous iron transport protein a g1789812 feoA -0.652
ferrous iron transport protein b g1789813 feoB 0.9641
ferric enterobactin transport ATP-BP g1786803 fepC -0.8465
ferrichrome-iron receptor g1786344 fhuA 1.0082
Fe(III)-ferrioxamine Band Fe(III)-rhodotrulic acid g1787344 fhuE -0.4726
potassium-transporting ATPase A chain EC3.6.1.36 g1786915 kdpA -0.3039
potassium-transporting ATPase B chain EC3.6.1.36 g1786914 kdpB 0.365
potassium-transporting ATPase C chain EC3.6.1.36 g1786913 kdpC -0.7125
glutathione-regulated potassium-efflux system g1789749 kefB -0.576
(glutathione-regulated) potassium efflux system g1786232 kefC -0.1827
"Mg(2+) transport ATPase, P-type 1 EC3.6.1.-" g1790690 mgtA -0.3301
molybdate-binding periplasmic protein g1786979 modA 0.7287
molybdenum transport system permease protein g1786980 modB -0.1225
molybdenum transport ATP-binding protein g1786981 modC -0.3096
putative molybdenum transport ATP-binding protein; photorepair protein PhrA g1786975 modF -0.908
"Na+, H+ antiporter " g1787435 nhaB 0.2004
"Na+, H+ antiporter 1" g1786201 nhaA -0.4718
nickel transport system permease protein g1789888 nikB 0.4956
"sodium, Pro symporter" g1787251 putP 0.3033
energy transducer g1787505 tonB -1.5366
TRK system potassium uptake prt g1789685 trkA -0.5746
trk system potassium uptake protein g1787626 trkG -2.3163
"14.5 Nucleosides, purines and pyrimidines"
nucleoside permease g1788737 nupC 1.423
transport of nucleosides g1789336 nupG 0.9154
cytosine permease g1786530 codB -0.5635
xanthosine permease g1788745 xapB -0.5273
14.6 Other
ATP-BP g1786398 abc 0.4756
aerotaxis receptor protein g1789453 air -0.2819
high-affinity choline transport prt g1786506 betT 0.0403
"receptor for vitamin B12, E colicins, and phage BF23" g1790405 btuB -0.5739
vitamin B12 transport system permease protein g1788004 btuC -1.0457
vitamin B12 transport g1788002 btuD -0.7774
vitamin B12 transport periplasmic protein g1788003 btuE -0.2525
probable carnitine transporter g1786224 caiT 0.3487
heme exporter protein A g1788529 ccmA -1.3407
heme exporter protein B g1788528 ccmB -0.4621
heme exporter protein C g1788527 ccmC 0.1306
heme exporter protein D g1788526 ccmD 0.4122
sulfate transport ATP-binding protein CysA g1788761 cysA 0.5254
sulfate transport system permease protein g1788762 cysW 0.023
sulfate transport system permease protein CysT g1788764 cysU -0.0522
thiosulfate-binding protein precursor g1788765 cysP 1.2428
hexuronate transporter g1789479 exuT 1.4188
long-chain fatty acid transport protein g1788686 fadL 0.3513
ferric enterobactin transport protein g1786802 fepE -1.1488
ferric enterobactin transport protein g1786804 fepG -0.2715
ferric enterobactin transport protein g1786805 fepD -0.4819
ferrienterobactin-binding periplasmic protein g1786807 fepB -0.6401
ferrichrome transport protein g1786347 fhuB -0.2572
ferrichrome transport ATP-binding protein g1786345 fhuC -0.2094
ferrichrome-binding periplasmic protein g1786346 fhuD -0.8038
electron transport from formate to hydrogen g1789067 hydN 1.0052
outer membrane lipoprotein carrier protein g1787118 lolA 0.3516
ATP-depepndent translocator g1787143 msbA 0.4178
pantothenate permease g1789656 panF -0.5999
phosphonates transport ATP-binding protein g1790544 phnC 0.3838
phosphonates transport ATP-binding protein g1790532 phnN -0.5725
phosphonates transport ATP-binding protein g1790534 phnL 0.6104
phosphonates transport ATP-binding protein g1790535 phnK 0.1296
probable low-affinity inorganic phosphate transporter2 g1789360 pitB -0.3398
NMN transport across the cytoplasmic membrane g1786965 pnuC -0.7998
thiamine-binding periplasmic protein precursor g1786255 tbpA 0.0382
probable transport protein YifK (o461) g1790230 yifK 0.2356
15 Other categories
15.1 Adaptations and atypical conditions
cold shock-like protein g1787839 cspB -2.8134
cold shock-like protein; multicopy suppresses mukB g1788126 cspC 1.5731
cold shock-like protein g1787107 cspD -1.9571
cold shock-like protein g1786841 cspE 0.4536
cold shock-like protein g1787840 cspF -1.2443
heat shock protein g1788875 hscA 0.5994
heat shock prt g1788133 htpX 1.1251
"membrane protein affecting cell division, growth and high temperature survival" g1787292 htrB -0.4112
heat shock inducible g1790122 hslT 0.7562
heat shock inducible g1790120 hslS 0.4181
survival prt g1786238 surA 1.1662
universal stress prt g1789909 uspA 0.9431
eat shock protein g1786194 htgA -1.5888
heat shock protein C g1790422 htrC -1.7032
extreme acid resistance g1787768 xasA -0.2938
15.2 Colicin-related functions
colicin I receptor g1788478 cirA 0.6615
colicin tolerance prt g1786961 tolB 0.8394
colicin V production prt g1788652 cvpA -0.7863
specific tolerance to colicin E1; expression of outer membrane proteins g1789413 tolC 0.2219
"inner membrane prt= TonB-independent uptake of colicinsA,E1,E2,E3,and K" g1786959 tolR -0.0516
"inner membrane prt= TonB-independent uptake of colicinsA,E1,E2,E3,and K" g1786958 tolQ 0.0148
outer membrane integrity prt g1786960 tolA -1.1278
15.3 Drug and analog sensitivity
acriflavin resistance protein A g1786668 acrA 0.6373
acriflavine resistance prt g1786667 acrB 1.0378
acriflavine resistance protein g1789665 acrE -0.4506
"resistance to acriflavin, hydrophobic antibiotics,basicdyesanddetergents" g1789666 acrF -0.5265
beta-lactamase precursor EC3.5.2.6 g1790593 ampC -1.4174
beta-lactamase precursor g1787644 hslJ -0.4868
ampD signalling prt g1786300 ampD -0.766
bacitracin resistance protein (putative undecaprenolkinase) g1789437 bacA 0.3638
fosmidomycin resistance protein g1786686 fsr -0.7061
modulator of drug activity A g1787075 mdaA -0.6486
modulator of drug activity B g1789406 mdaB 0.3596
"organic solvent tolerance protein precursor""" g1786239 imp 0.507
multiple antibiotic resistance protein g1787811 marA -0.3463
multiple antibiotic resistance protein g1787810 marR 0.0401
5-methyltryptophan resistance; tryptophan-specific permease g1789552 mtr 0.1295
polymyxin B resistance protein g1788593 pmrD -2.123
multidrug resistance prt g1789042 emrB -0.1862
multidrug resistance prt g1789041 ermA 0.7963
multidrug resistance protein d g1790107 emrD -0.8667
multidrug resistance protein g1788710 emrY -1.8172
multidrug resistance protein g1788711 emrK -1.8443
"rRNA(adenosine-N6,N6)-dimethyltransferase EC2.1.1.-" g1786236 ksgA 0.1307
tellurite resistance prt g1787699 tehA -0.9432
tellurite resistance prt g1787700 tehB -0.086
15.4 Phage-related functions and prophages
host factor-I (HF-I) g1790614 hfq 0.5297
SlpA integrase; prophage cp4-57 integrase g1788974 intA -1.2937
prophage P4 integrase g1790722 intB -1.8614
prophage DLP12 integrase g1786748 intD -1.6832
bacteriophage T4 late gene expression blocking protein g1787385 lit -2.4376
bacteriophage N4 adsorption protein B g1786781 nfrB -0.3976
positive regulator of phage P2 late gene transcription g1788398 ogrK -1.7705
prophage QIN DNA packaging protein NU1 homolog g1787830 nohA -0.4518
phage shock protein A g1787562 pspA 0.129
phage shock protein B g1787563 pspB -0.0937
phage shock protein C g1787564 pspC 0.1637
phage shock protein D g1787565 pspD -0.76
phage shock protein E g1787567 pspE -0.0759
host gene required for lysis of phiX174 infection g1789747 slyX -0.4537
putative prophage sf6-like integrase g1788690 yfdB -1.0975
bacteriophage N4 adsorption protein A g1786780 nfrA -0.5136
15.5 Radiation sensitivity
DNA repair prt g1790069 radC -1.3924
15.6 Transposon-related functions
insertion element IS1 protein insA g1786204 insA_1 -0.9985
insertion element IS1 protein InsA g1786460 insA_2 -1.0176
insertion element IS1 protein InsA g1786471 insA_3 -1.0176
insertion element IS1 protein InsA g1788204 insA_4 -0.9985
insertion element is1 protein insA g1789852 insA_5 -0.9985
insertion element is1f protein insa g1790747 insA_6 -1.3076
insertion element IS1 protein InsB g1786457 insB_1 -0.2881
insertion element IS1 protein InsB g1786470 insB_2 -0.2881
insertion element IS1 protein InsB g1787223 insB_3 -0.2465
insertion element IS1 protein InsB g1788203 insB_4 -0.3518
insertion element IS1 protein InsB g1789853 insB_5 -0.3518
putative transposase for insertion sequence IS3 g1786570 tra5_1 -0.5628
putative transposase for insertion sequence IS3 g1786753 tra5_2 -0.5628
putative transposase for insertion sequence IS3 g1787263 tra5_3 -0.5628
putative transposase for insertion sequence is3 g1788405 tra5_4 -0.5628
transposase for insertion sequence element IS30 g1786450 tra8_1 -1.3452
transposase for insertion sequence element IS30 g1787671 tra8_2 -1.396
IS30 transposase g1790736 tra8_3 -1.396
16 Other
glp regulon prt g1790360 glpX 0.5385
heat shock prt g1790366 hslU 1.8133
heat shock prt EC3.4.99.- g1790367 hslV 0.127
isochorismate Sase EC5.4.99.6 g1786809 entC -0.2751
isochorismate synthase g1788600 menF -0.7165
transport ATP-BP g1787112 cydC -0.8061
transport ATP-BP g1787113 cydD -0.9188